SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 8 GLY A 215
PHE A 127
THR A  36
ILE A 197
 None
 0.83A 2a8tB-1uh9A:
undetectable		 2a8tB-1uh9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		6 / 12 ASP A  35
GLY A  37
SER A  38
TYR A  77
ASP A 218
GLY A 220
 None
 0.29A 2v0zC-1uh9A:
40.7		 2v0zC-1uh9A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		3 / 3 GLU A  16
ASP A  35
TYR A  77
 None
 0.87A 2yvlB-1uh9A:
undetectable		 2yvlB-1uh9A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		5 / 12 VAL A   6
GLY A 172
MET A 140
LEU A 143
ILE A 149
 None
 1.04A 3ku1H-1uh9A:
undetectable		 3ku1H-1uh9A:
24.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		8 / 12 ASP A  33
ASP A  35
GLY A  37
GLY A  78
ASP A  79
ASP A 218
THR A 221
ILE A 298
 None
 0.44A 3prsA-1uh9A:
42.5		 3prsA-1uh9A:
40.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		8 / 12 ASP A  33
ASP A  35
GLY A  78
PHE A 114
LEU A 122
ILE A 216
THR A 221
ILE A 298
 None
 0.40A 3pwwA-1uh9A:
42.5		 3pwwA-1uh9A:
40.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		7 / 8 GLY A  37
SER A  38
ILE A  75
TYR A  77
SER A  81
ASP A 218
THR A 222
 None
 0.37A 3pwwA-1uh9A:
42.5		 3pwwA-1uh9A:
40.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		6 / 8 SER A  38
ILE A  75
TYR A  77
ASP A  79
SER A  81
THR A 222
 None
 0.67A 3pwwA-1uh9A:
42.5		 3pwwA-1uh9A:
40.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		6 / 12 ASP A  35
GLY A  37
GLY A  78
ASP A 218
THR A 221
ILE A 298
 None
 0.37A 3q70A-1uh9A:
38.2		 3q70A-1uh9A:
33.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		5 / 12 ILE A 216
ASP A 218
GLY A 220
GLY A  78
ASP A  35
 None
 0.69A 3q70A-1uh9A:
38.2		 3q70A-1uh9A:
33.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 SER A  38
ILE A  75
TYR A  77
THR A 222
 None
 0.23A 3q70A-1uh9A:
38.2		 3q70A-1uh9A:
33.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		8 / 12 ASP A  35
GLY A  37
ILE A  75
GLY A  78
ASP A  79
SER A  81
ASP A 218
ILE A 298
 None
 0.53A 3tneA-1uh9A:
38.9		 3tneA-1uh9A:
30.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 SER A  38
TYR A  77
THR A 221
THR A 222
 None
 0.38A 3tneA-1uh9A:
38.9		 3tneA-1uh9A:
30.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		8 / 12 ASP A  35
GLY A  37
ILE A  75
GLY A  78
ASP A  79
SER A  81
ASP A 218
ILE A 298
 None
 0.50A 3tneB-1uh9A:
39.0		 3tneB-1uh9A:
30.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 7 SER A  38
TYR A  77
THR A 221
THR A 222
 None
 0.44A 3tneB-1uh9A:
39.0		 3tneB-1uh9A:
30.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 THR A 219
GLY A 300
ILE A 298
LEU A 217
 None
 0.79A 4acbC-1uh9A:
undetectable		 4acbC-1uh9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 THR A  36
GLY A 220
TYR A 169
GLY A  19
 None
 0.89A 4fjpA-1uh9A:
undetectable		 4fjpA-1uh9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		5 / 12 VAL A 271
ILE A 299
LEU A 224
VAL A 209
ALA A 202
 None
 1.02A 4m11C-1uh9A:
undetectable		 4m11C-1uh9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		5 / 12 VAL A 271
ILE A 299
LEU A 224
VAL A 209
ALA A 202
 None
 1.03A 4m11D-1uh9A:
undetectable		 4m11D-1uh9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		5 / 12 LEU A 224
ILE A 299
ILE A 197
VAL A 199
LEU A 260
 None
 0.88A 4y0sA-1uh9A:
undetectable		 4y0sA-1uh9A:
18.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y4J_A_LNRA412_1
(ENDOTHIAPEPSIN)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		8 / 9 ASP A  33
ASP A  35
TYR A  77
ASP A  79
SER A  81
SER A 113
PHE A 114
LEU A 122
 None
 0.26A 4y4jA-1uh9A:
42.6		 4y4jA-1uh9A:
40.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 PHE A 127
LEU A 125
TRP A 195
GLY A  37
 None
 0.97A 5o4yA-1uh9A:
undetectable		 5o4yA-1uh9A:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 ILE A 264
ILE A 225
LEU A 226
PHE A 213
 None
 0.81A 5vkqA-1uh9A:
undetectable
5vkqB-1uh9A:
undetectable		 5vkqA-1uh9A:
12.14
5vkqB-1uh9A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 ILE A 264
ILE A 225
LEU A 226
PHE A 213
 None
 0.79A 5vkqB-1uh9A:
undetectable
5vkqC-1uh9A:
undetectable		 5vkqB-1uh9A:
12.14
5vkqC-1uh9A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 ILE A 264
ILE A 225
LEU A 226
PHE A 213
 None
 0.78A 5vkqC-1uh9A:
undetectable
5vkqD-1uh9A:
undetectable		 5vkqC-1uh9A:
12.14
5vkqD-1uh9A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1uh9 HIZOPUSPEPSIN I
(Rhizopus
microsporus) 		4 / 6 ILE A 264
ILE A 225
LEU A 226
PHE A 213
 None
 0.79A 5vkqA-1uh9A:
undetectable
5vkqD-1uh9A:
undetectable		 5vkqA-1uh9A:
12.14
5vkqD-1uh9A:
12.14