SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uhb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1uhb TRYPSIN
(Sus
scrofa) 		6 / 9 VAL A  52
LEU A  67
ILE A  63
ALA A  85
SER A 109
LEU A 108
 None
 1.23A 1eqgA-1uhbA:
undetectable		 1eqgA-1uhbA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1uhb TRYPSIN
(Sus
scrofa) 		6 / 11 VAL A  52
LEU A  67
ILE A  63
ALA A  85
SER A 109
LEU A 108
 None
 1.23A 1eqgB-1uhbA:
undetectable		 1eqgB-1uhbA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1uhb TRYPSIN
(Sus
scrofa) 		6 / 12 VAL A  52
LEU A  67
ILE A  63
ALA A  85
SER A 109
LEU A 108
 None
 1.19A 1eqhA-1uhbA:
undetectable		 1eqhA-1uhbA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1uhb TRYPSIN
(Sus
scrofa) 		6 / 12 VAL A  52
LEU A  67
ILE A  63
ALA A  85
SER A 109
LEU A 108
 None
 1.18A 1eqhB-1uhbA:
undetectable		 1eqhB-1uhbA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1uhb TRYPSIN
(Sus
scrofa) 		5 / 12 VAL A  52
LEU A  67
ALA A  85
SER A 109
LEU A 108
 None
 0.99A 3n8wA-1uhbA:
undetectable		 3n8wA-1uhbA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1uhb TRYPSIN
(Sus
scrofa) 		5 / 12 VAL A  52
LEU A  67
ALA A  85
SER A 109
LEU A 108
 None
 0.98A 3n8zA-1uhbA:
undetectable		 3n8zA-1uhbA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1uhb TRYPSIN
(Sus
scrofa) 		5 / 12 VAL A  52
LEU A  67
ALA A  85
SER A 109
LEU A 108
 None
 0.98A 3pghC-1uhbA:
undetectable		 3pghC-1uhbA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1uhb TRYPSIN
(Sus
scrofa) 		5 / 10 VAL A  52
LEU A  67
ALA A  85
SER A 109
LEU A 108
 None
 0.97A 4ph9A-1uhbA:
undetectable		 4ph9A-1uhbA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1uhb TRYPSIN
(Sus
scrofa) 		5 / 10 VAL A  52
LEU A  67
ALA A  85
SER A 109
LEU A 108
 None
 0.96A 4ph9B-1uhbA:
undetectable		 4ph9B-1uhbA:
12.18