SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ui1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 10 GLY A  59
LEU A  62
LEU A  61
ILE A  65
ARG A  73
 None
 1.11A 2f8dB-1ui1A:
undetectable		 2f8dB-1ui1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 ILE A 178
PHE A 151
HIS A 172
 None
 0.74A 3h0aA-1ui1A:
undetectable		 3h0aA-1ui1A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 8 GLY A  40
PHE A  54
ASN A  80
HIS A 155
 None
 0.64A 4wryA-1ui1A:
10.1		 4wryA-1ui1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 8 GLY A  40
PHE A  54
ASN A  80
HIS A 155
 None
 0.57A 4wrzA-1ui1A:
9.7		 4wrzA-1ui1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 GLY A  40
PHE A  54
ASN A  80
HIS A 155
 None
 0.54A 4ws0A-1ui1A:
9.6		 4ws0A-1ui1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 8 GLY A  40
PHE A  54
ASN A  80
HIS A 155
 None
 0.55A 4ws1A-1ui1A:
8.9		 4ws1A-1ui1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 HIS A 146
GLU A 144
TRP A 145
 None
 1.15A 5odiD-1ui1A:
2.8		 5odiD-1ui1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 HIS A 146
GLU A 144
TRP A 145
 None
 1.20A 5odqD-1ui1A:
2.8		 5odqD-1ui1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		3 / 3 HIS A 146
GLU A 144
TRP A 145
 None
 1.09A 5odrD-1ui1A:
2.1		 5odrD-1ui1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		5 / 12 LEU A 159
GLY A  59
ALA A 157
PRO A  53
GLU A  29
 None
 1.22A 5x6yA-1ui1A:
undetectable		 5x6yA-1ui1A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 1ui1 URACIL-DNA
GLYCOSYLASE
(Thermus
thermophilus) 		4 / 7 VAL A 118
ILE A  65
ILE A 178
ASP A 177
 None
 0.81A 5ywmX-1ui1A:
undetectable		 5ywmX-1ui1A:
17.77