SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 12 LEU A  87
LEU A  83
CYH A  59
VAL A  14
LEU A  19
 None
 1.33A 1ie9A-1uizA:
undetectable		 1ie9A-1uizA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		4 / 7 ALA A  27
ILE A  37
ILE A  39
ASP A  21
 None
 0.92A 1upfB-1uizA:
undetectable		 1upfB-1uizA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 12 THR A  30
ALA A  29
LEU A  79
LEU A  78
LEU A  61
 None
 1.15A 3hm1A-1uizA:
undetectable		 3hm1A-1uizA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 0.50A 3rf4A-1uizA:
20.3
3rf4C-1uizA:
20.4		 3rf4A-1uizA:
33.04
3rf4C-1uizA:
33.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 1.38A 3rf4A-1uizA:
20.3
3rf4C-1uizA:
20.4		 3rf4A-1uizA:
33.04
3rf4C-1uizA:
33.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 0.50A 3rf4A-1uizA:
20.3
3rf4B-1uizA:
20.3		 3rf4A-1uizA:
33.04
3rf4B-1uizA:
33.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 1.37A 3rf4A-1uizA:
20.3
3rf4B-1uizA:
20.3		 3rf4A-1uizA:
33.04
3rf4B-1uizA:
33.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 0.47A 3rf4B-1uizA:
20.3
3rf4C-1uizA:
20.4		 3rf4B-1uizA:
33.04
3rf4C-1uizA:
33.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1uiz MACROPHAGE MIGRATION
INHIBITORY FACTOR
(Xenopus
laevis) 		5 / 11 PRO A   1
LYS A  32
SER A  63
ILE A  64
VAL A 106
 None
 1.35A 3rf4B-1uizA:
20.3
3rf4C-1uizA:
20.4		 3rf4B-1uizA:
33.04
3rf4C-1uizA:
33.04