SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1uj3 IGG FAB HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ARG B 340
GLU B 389
GLN B 343
 None
 0.76A 2p16A-1uj3B:
undetectable		 2p16A-1uj3B:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1uj3 IGG FAB HEAVY CHAIN
(Homo
sapiens) 		3 / 3 THR B 414
GLU B 452
HIS B 504
 None
 0.70A 3g1uB-1uj3B:
undetectable		 3g1uB-1uj3B:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1uj3 IGG FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 8 THR B 495
ASN B 459
VAL B 486
LEU B 442
GLY B 494
 None
 1.16A 4r3aA-1uj3B:
undetectable		 4r3aA-1uj3B:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1uj3 IGG FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA B 392
THR B 391
VAL B 413
GLU B 389
 None
 0.81A 5ecoD-1uj3B:
undetectable		 5ecoD-1uj3B:
18.35