SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ujj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 ASP A  40
ILE A  14
VAL A  85
 None
 0.62A 2avvD-1ujjA:
undetectable		 2avvD-1ujjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 HIS A  53
ILE A  14
LEU A  46
 None
 0.73A 2kceA-1ujjA:
undetectable		 2kceA-1ujjA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.20A 2zj0A-1ujjA:
undetectable		 2zj0A-1ujjA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.23A 3ce6A-1ujjA:
undetectable		 3ce6A-1ujjA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.23A 3ce6C-1ujjA:
undetectable		 3ce6C-1ujjA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 6 LEU A  70
GLU A  71
LYS A 114
LEU A 118
 None
 0.86A 3h5gA-1ujjA:
undetectable
3h5gC-1ujjA:
undetectable		 3h5gA-1ujjA:
14.58
3h5gC-1ujjA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		5 / 10 ILE A  64
PHE A  90
ALA A  47
LEU A  51
ALA A  52
 None
 1.32A 3lw5B-1ujjA:
undetectable		 3lw5B-1ujjA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 0.98A 4lvcA-1ujjA:
undetectable		 4lvcA-1ujjA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.04A 4lvcB-1ujjA:
undetectable		 4lvcB-1ujjA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.01A 4lvcC-1ujjA:
undetectable		 4lvcC-1ujjA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 8 LEU A 119
VAL A  98
VAL A 145
LEU A  94
 None
 1.08A 4pwdC-1ujjA:
undetectable		 4pwdC-1ujjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 4 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.03A 5m5kA-1ujjA:
undetectable		 5m5kA-1ujjA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 4 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.07A 5m66B-1ujjA:
undetectable		 5m66B-1ujjA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 1.00A 6f3mD-1ujjA:
undetectable		 6f3mD-1ujjA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 5 GLN A  36
THR A   9
THR A  18
LEU A  51
 None
 0.94A 6gbnA-1ujjA:
undetectable		 6gbnA-1ujjA:
15.75