SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ujo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1ujo TRANSGELIN
(Mus
musculus) 		5 / 12 TYR A 129
LEU A  46
LEU A  49
VAL A  50
SER A  52
 None
 1.27A 1ie9A-1ujoA:
undetectable		 1ie9A-1ujoA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 1ujo TRANSGELIN
(Mus
musculus) 		3 / 3 VAL A  15
GLU A  12
GLU A  16
 None
 0.62A 2nv4A-1ujoA:
undetectable		 2nv4A-1ujoA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ujo TRANSGELIN
(Mus
musculus) 		4 / 8 LEU A  46
LEU A  49
LEU A  53
VAL A  90
 None
 0.63A 4klaA-1ujoA:
undetectable		 4klaA-1ujoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ujo TRANSGELIN
(Mus
musculus) 		5 / 12 LEU A  49
ALA A  85
PHE A  81
GLY A 118
ALA A 116
 None
 0.88A 4nkxB-1ujoA:
undetectable		 4nkxB-1ujoA:
18.29