SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ujs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_B_9CRB202_1 (RXR-LIKE PROTEIN)	1ujs	ACTIN-BINDING LIM PROTEIN HOMOLOGUE (Homo sapiens)	5 / 12	ALA A 79 GLN A 78 VAL A 39 HIS A 47 LEU A 48	None	1.04A	1xiuB-1ujsA: undetectable	1xiuB-1ujsA: 18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZSE_A_PAUA600_0 (PANTOTHENATE KINASE)	1ujs	ACTIN-BINDING LIM PROTEIN HOMOLOGUE (Homo sapiens)	4 / 7	PHE A 57 MET A 59 PHE A 53 ASN A 73	None	1.23A	2zseA-1ujsA: undetectable	2zseA-1ujsA: 15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KSZ_A_CYSA620_0 (LACTOPEROXIDASE)	1ujs	ACTIN-BINDING LIM PROTEIN HOMOLOGUE (Homo sapiens)	3 / 3	ARG A 72 GLU A 45 PHE A 53	None	1.02A	4kszA-1ujsA: undetectable	4kszA-1ujsA: 9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	1ujs	ACTIN-BINDING LIM PROTEIN HOMOLOGUE (Homo sapiens)	5 / 12	PHE A 57 PHE A 64 ILE A 61 VAL A 56 PHE A 53	None	1.21A	6ap6A-1ujsA: undetectable	6ap6A-1ujsA: 17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	1ujs	ACTIN-BINDING LIM PROTEIN HOMOLOGUE (Homo sapiens)	5 / 12	PHE A 57 PHE A 64 ILE A 61 VAL A 56 PHE A 53	None	1.20A	6ap6B-1ujsA: undetectable	6ap6B-1ujsA: 17.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XIU_B_9CRB202_1","RXR-LIKE PROTEIN","1ujs","ACTIN-BINDING LIM PROTEIN HOMOLOGUE","Homo sapiens",5,"ALA A  79;GLN A  78;VAL A  39;HIS A  47;LEU A  48","None","1.04A","1xiuB-1ujsA:undetectable","1xiuB-1ujsA:18.41"],["2ZSE_A_PAUA600_0","PANTOTHENATE KINASE","1ujs","ACTIN-BINDING LIM PROTEIN HOMOLOGUE","Homo sapiens",4,"PHE A  57;MET A  59;PHE A  53;ASN A  73","None","1.23A","2zseA-1ujsA:undetectable","2zseA-1ujsA:15.81"],["4KSZ_A_CYSA620_0","LACTOPEROXIDASE","1ujs","ACTIN-BINDING LIM PROTEIN HOMOLOGUE","Homo sapiens",3,"ARG A  72;GLU A  45;PHE A  53","None","1.02A","4kszA-1ujsA:undetectable","4kszA-1ujsA:9.85"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","1ujs","ACTIN-BINDING LIM PROTEIN HOMOLOGUE","Homo sapiens",5,"PHE A  57;PHE A  64;ILE A  61;VAL A  56;PHE A  53","None","1.21A","6ap6A-1ujsA:undetectable","6ap6A-1ujsA:17.02"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","1ujs","ACTIN-BINDING LIM PROTEIN HOMOLOGUE","Homo sapiens",5,"PHE A  57;PHE A  64;ILE A  61;VAL A  56;PHE A  53","None","1.20A","6ap6B-1ujsA:undetectable","6ap6B-1ujsA:17.02"]]