SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ukf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		5 / 12 LEU A 225
ILE A 244
ILE A 248
SER A 253
LEU A 202
 None
 0.90A 1xdkB-1ukfA:
0.0		 1xdkB-1ukfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		5 / 12 LEU A 225
ILE A 244
ILE A 248
SER A 253
LEU A 202
 None
 0.90A 1xdkF-1ukfA:
undetectable		 1xdkF-1ukfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		3 / 3 LEU A  82
LEU A 204
PHE A 233
 None
 0.70A 2pgrA-1ukfA:
undetectable		 2pgrA-1ukfA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		4 / 7 CYH A 260
PHE A 264
PHE A 155
SER A 203
 None
 1.16A 3hggA-1ukfA:
1.1		 3hggA-1ukfA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		4 / 8 LEU A 202
ARG A 265
SER A 235
GLY A 197
 None
 0.99A 4klrB-1ukfA:
undetectable		 4klrB-1ukfA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		5 / 12 ILE A  97
ASN A  96
GLY A 131
SER A 158
ASN A 139
 None
 1.14A 4obwC-1ukfA:
undetectable		 4obwC-1ukfA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		5 / 12 ALA A  99
ILE A  97
ASN A  96
GLY A 131
ASN A 139
 None
 1.21A 4obwD-1ukfA:
undetectable		 4obwD-1ukfA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		4 / 6 GLU A 104
ARG A 134
LEU A 106
ARG A 117
 None
 1.05A 5l6eA-1ukfA:
undetectable
5l6eB-1ukfA:
undetectable		 5l6eA-1ukfA:
20.78
5l6eB-1ukfA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		5 / 12 SER A 109
ALA A  88
PHE A 226
CYH A 218
GLU A 219
 None
 1.25A 5wbvA-1ukfA:
0.0		 5wbvA-1ukfA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		5 / 12 SER A 109
ALA A  88
PHE A 226
CYH A 218
GLU A 219
 None
 1.23A 5wbvB-1ukfA:
0.0		 5wbvB-1ukfA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		4 / 4 ALA A 141
ALA A 145
ALA A 157
ALA A 160
 None
 0.84A 6gtqA-1ukfA:
0.3
6gtqB-1ukfA:
0.4		 6gtqA-1ukfA:
21.43
6gtqB-1ukfA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1ukf AVIRULENCE PROTEIN
AVRPPH3
(Pseudomonas
savastanoi) 		4 / 4 ALA A 157
ALA A 160
ALA A 141
ALA A 145
 None
 0.85A 6gtqA-1ukfA:
0.3
6gtqB-1ukfA:
0.4		 6gtqA-1ukfA:
21.43
6gtqB-1ukfA:
21.43