SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ukr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		4 / 7 ILE A  82
TYR A  80
PHE A 157
PHE A 162
 None
 0.89A 1e71M-1ukrA:
undetectable		 1e71M-1ukrA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		4 / 7 ILE A  82
TYR A  80
PHE A 157
PHE A 162
 None
 0.86A 1e72M-1ukrA:
undetectable		 1e72M-1ukrA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		4 / 8 TYR A 108
ARG A 134
GLU A  84
VAL A 101
 None
 1.10A 2fl5E-1ukrA:
0.9
2fl5F-1ukrA:
1.1		 2fl5E-1ukrA:
24.54
2fl5F-1ukrA:
26.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 11 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.22A 3mg0H-1ukrA:
undetectable
3mg0I-1ukrA:
undetectable		 3mg0H-1ukrA:
19.74
3mg0I-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		4 / 6 VAL A  39
ASN A  11
TYR A  70
GLU A  79
 None
 1.19A 3q5sA-1ukrA:
undetectable		 3q5sA-1ukrA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 TYR A   6
ILE A   4
TYR A 164
ILE A  52
ILE A 182
 None
 1.16A 3vrjA-1ukrA:
undetectable
3vrjC-1ukrA:
undetectable		 3vrjA-1ukrA:
19.22
3vrjC-1ukrA:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8W_G_MTXG301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 9 PHE A  38
GLY A  43
GLY A  41
LEU A  42
GLU A  21
 None
 1.47A 4l8wG-1ukrA:
undetectable		 4l8wG-1ukrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.19A 4qvpH-1ukrA:
undetectable
4qvpI-1ukrA:
undetectable		 4qvpH-1ukrA:
19.33
4qvpI-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.19A 4qvpV-1ukrA:
undetectable
4qvpW-1ukrA:
undetectable		 4qvpV-1ukrA:
19.33
4qvpW-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.23A 4qvyV-1ukrA:
undetectable
4qvyW-1ukrA:
undetectable		 4qvyV-1ukrA:
19.33
4qvyW-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 11 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.22A 4qw0H-1ukrA:
undetectable
4qw0I-1ukrA:
undetectable		 4qw0H-1ukrA:
19.33
4qw0I-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 11 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.20A 4qw0V-1ukrA:
undetectable
4qw0W-1ukrA:
undetectable		 4qw0V-1ukrA:
19.33
4qw0W-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.18A 4qw1H-1ukrA:
undetectable
4qw1I-1ukrA:
undetectable		 4qw1H-1ukrA:
19.33
4qw1I-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.19A 4qw1V-1ukrA:
undetectable
4qw1W-1ukrA:
undetectable		 4qw1V-1ukrA:
19.33
4qw1W-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		3 / 3 GLU A  79
ALA A  78
PHE A 127
 None
 0.63A 4v1fA-1ukrA:
undetectable		 4v1fA-1ukrA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		3 / 3 GLU A  79
ALA A  78
PHE A 127
 None
 0.63A 4v1fC-1ukrA:
undetectable		 4v1fC-1ukrA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 8 ALA A 171
VAL A 169
PHE A  38
ALA A 175
GLY A 176
 None
 1.15A 4zjzB-1ukrA:
undetectable		 4zjzB-1ukrA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		4 / 8 ASN A  90
PRO A  91
SER A  65
TYR A  58
 None
 1.23A 5amiB-1ukrA:
undetectable		 5amiB-1ukrA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.21A 5cz7V-1ukrA:
undetectable
5cz7W-1ukrA:
undetectable		 5cz7V-1ukrA:
19.33
5cz7W-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.23A 5l5fV-1ukrA:
undetectable
5l5fW-1ukrA:
undetectable		 5l5fV-1ukrA:
19.33
5l5fW-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.20A 5l5zH-1ukrA:
undetectable
5l5zI-1ukrA:
undetectable		 5l5zH-1ukrA:
19.33
5l5zI-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.21A 5l5zV-1ukrA:
undetectable
5l5zW-1ukrA:
undetectable		 5l5zV-1ukrA:
19.33
5l5zW-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.20A 5l66H-1ukrA:
undetectable
5l66I-1ukrA:
undetectable		 5l66H-1ukrA:
19.33
5l66I-1ukrA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 SER A  65
ALA A 175
GLY A 176
ALA A  60
ASP A  85
 None
 1.19A 5l66V-1ukrA:
undetectable
5l66W-1ukrA:
undetectable		 5l66V-1ukrA:
19.33
5l66W-1ukrA:
20.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 VAL A  39
TRP A  72
TYR A  81
PRO A 119
TYR A 164
 None
 0.78A 5tzoA-1ukrA:
26.3		 5tzoA-1ukrA:
40.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		5 / 12 VAL A  39
TRP A  72
TYR A  81
PRO A 119
TYR A 164
 None
 0.85A 5tzoC-1ukrA:
26.1		 5tzoC-1ukrA:
40.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ukr ENDO-1,4-B-XYLANASE
I
(Aspergillus
niger) 		3 / 3 GLN A  77
ILE A  82
HIS A 148
 None
 0.68A 5z12B-1ukrA:
undetectable		 5z12B-1ukrA:
17.88