SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ul1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		3 / 3 TRP X 298
TYR X  83
LEU X 153
 None
 0.99A 1kxhA-1ul1X:
undetectable		 1kxhA-1ul1X:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 12 THR X  71
PRO X 301
VAL X  31
TYR X  83
ILE X 150
 None
 1.08A 1z9hA-1ul1X:
undetectable		 1z9hA-1ul1X:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 12 THR X  71
PRO X 301
VAL X  31
TYR X  83
ILE X 150
 None
 1.07A 1z9hB-1ul1X:
undetectable		 1z9hB-1ul1X:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 12 THR X  71
PRO X 301
VAL X  31
TYR X  83
ILE X 150
 None
 1.08A 1z9hC-1ul1X:
0.1		 1z9hC-1ul1X:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		6 / 12 THR X  71
PRO X 301
ILE X  79
VAL X  31
TYR X  83
ILE X 150
 None
 1.20A 1z9hD-1ul1X:
undetectable		 1z9hD-1ul1X:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		3 / 3 ASP X 154
ILE X 150
VAL X 172
 None
 0.54A 2avvD-1ul1X:
undetectable		 2avvD-1ul1X:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 12 ILE X 212
LEU X 209
ILE X   3
VAL X 247
LEU X 226
 None
 1.14A 3a51C-1ul1X:
undetectable		 3a51C-1ul1X:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		4 / 8 ASP X  34
ASP X 179
CYH X 163
TYR X 234
 MG  X1001 (-3.4A)
MG  X1002 ( 4.0A)
None
None
 1.14A 3havA-1ul1X:
0.0		 3havA-1ul1X:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 12 PRO X  81
VAL X  31
TYR X  26
ILE X 150
ILE X  23
 None
 1.45A 3q5pA-1ul1X:
0.0		 3q5pA-1ul1X:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		4 / 8 LEU X 229
LEU X 226
LEU X 218
ILE X 241
 None
 0.80A 4klaA-1ul1X:
undetectable		 4klaA-1ul1X:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 10 LEU X 226
LEU X 209
ILE X 212
LEU X 213
LEU X   9
 None
 0.84A 4odoA-1ul1X:
undetectable		 4odoA-1ul1X:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 10 LEU X 226
LEU X 209
ILE X 212
LEU X 213
LEU X   9
 None
 0.87A 4odoB-1ul1X:
undetectable		 4odoB-1ul1X:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 10 LEU X 226
LEU X 209
ILE X 212
LEU X 213
LEU X   9
 None
 0.90A 4odoC-1ul1X:
undetectable		 4odoC-1ul1X:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 8 LEU X 263
ILE X 250
ALA X 246
HIS X 280
LEU X 229
 None
 1.30A 4qrcA-1ul1X:
undetectable		 4qrcA-1ul1X:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		4 / 7 LEU X 190
THR X 184
LEU X 183
THR X 177
 None
 0.86A 4z90A-1ul1X:
undetectable
4z90B-1ul1X:
undetectable
4z90C-1ul1X:
undetectable
4z90D-1ul1X:
undetectable
4z90E-1ul1X:
undetectable		 4z90A-1ul1X:
21.99
4z90B-1ul1X:
21.99
4z90C-1ul1X:
21.99
4z90D-1ul1X:
21.99
4z90E-1ul1X:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		4 / 7 LEU X 226
ALA X 246
LEU X 230
LEU X 216
 None
 0.65A 4z90F-1ul1X:
undetectable
4z90G-1ul1X:
undetectable
4z90H-1ul1X:
undetectable
4z90J-1ul1X:
undetectable		 4z90F-1ul1X:
21.99
4z90G-1ul1X:
21.99
4z90H-1ul1X:
21.99
4z90J-1ul1X:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		4 / 7 TYR X  26
VAL X  31
ILE X  33
ALA X 176
 None
 0.72A 5ospA-1ul1X:
undetectable		 5ospA-1ul1X:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		4 / 7 TYR X  26
VAL X  31
ILE X  33
ALA X 176
 None
 0.68A 5osrA-1ul1X:
undetectable		 5osrA-1ul1X:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 1ul1 FLAP ENDONUCLEASE-1
(Homo
sapiens) 		5 / 12 MET X  74
MET X  75
GLU X 206
LEU X 194
VAL X 172
 None
 1.13A 5vlmG-1ul1X:
undetectable		 5vlmG-1ul1X:
21.07