SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1umb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		3 / 3 GLN A 127
HIS A 131
PRO A 129
 None
 0.77A 1d8cA-1umbA:
2.7		 1d8cA-1umbA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 6 LEU B 113
GLU B 165
ASP B 166
PRO B 167
 None
 1.03A 1ditH-1umbB:
undetectable
1ditP-1umbB:
undetectable		 1ditH-1umbB:
20.41
1ditP-1umbB:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		5 / 11 LEU A 100
ALA A  79
LEU A 265
THR A 172
VAL A  91
 None
 1.24A 1ictA-1umbA:
undetectable
1ictC-1umbA:
undetectable		 1ictA-1umbA:
14.67
1ictC-1umbA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 6 TYR A  94
TYR A  95
HIS A 273
GLU A 202
 TDP  A1402 (-4.5A)
TDP  A1402 (-4.3A)
TDP  A1402 (-4.3A)
None
 0.95A 1q13A-1umbA:
undetectable		 1q13A-1umbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 4 LEU A 262
VAL A 263
ILE A 200
TRP A 183
 None
 1.26A 1s9qB-1umbA:
undetectable		 1s9qB-1umbA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 ALA A 197
ARG A 255
LEU A 162
MET B  54
PHE A 189
 None
 1.42A 1y0xX-1umbA:
undetectable		 1y0xX-1umbA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 8 ALA B 231
ALA B 318
LEU B 218
VAL B 217
 None
 0.91A 2bxgA-1umbB:
undetectable		 2bxgA-1umbB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 VAL B 273
LEU B 259
VAL B 260
VAL B 217
LEU B 157
 None
 1.11A 2cbrA-1umbB:
undetectable		 2cbrA-1umbB:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus;
Thermus
thermophilus) 		6 / 12 PHE A 228
PHE A 189
ALA A 197
GLY B  65
GLY B  69
TYR A 184
 None
 1.41A 2igtA-1umbA:
2.8		 2igtA-1umbA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus;
Thermus
thermophilus) 		6 / 12 PHE A 228
PHE A 189
ALA A 197
GLY B  65
GLY B  69
TYR A 184
 None
 1.40A 2igtB-1umbA:
3.2		 2igtB-1umbA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 6 GLU A  21
TRP A 291
ARG A 302
MET A  45
 None
 1.41A 2ouzA-1umbA:
undetectable		 2ouzA-1umbA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		3 / 3 ARG B 200
ASN B 249
THR B 254
 None
 0.76A 2q63A-1umbB:
undetectable		 2q63A-1umbB:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 8 MET B 214
ARG B 237
SER B 179
MET B   6
 None
 1.10A 2qd2A-1umbB:
5.6		 2qd2A-1umbB:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 6 LEU A 241
LEU A  18
ASP A 239
ARG A 299
 None
 1.16A 2rlfB-1umbA:
undetectable
2rlfC-1umbA:
undetectable		 2rlfB-1umbA:
8.62
2rlfC-1umbA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 7 ALA B 246
ASP B 243
ASP B 235
LEU B 234
ARG B 199
 None
 1.30A 2uyqA-1umbB:
3.2		 2uyqA-1umbB:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 8 HIS A  73
GLN A  77
ARG A 269
THR A  56
 None
 1.44A 2vxaF-1umbA:
undetectable
2vxaG-1umbA:
undetectable
2vxaI-1umbA:
undetectable		 2vxaF-1umbA:
11.75
2vxaG-1umbA:
11.75
2vxaI-1umbA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 VAL A 247
ASN A 203
VAL A 267
GLY A 237
ALA A  76
 None
 1.26A 2x2iA-1umbA:
undetectable		 2x2iA-1umbA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 6 SER A 134
PRO A  86
GLY A  87
TRP A  90
 None
 1.11A 2y7pA-1umbA:
0.4		 2y7pA-1umbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 VAL B  98
ARG B 104
LEU B 113
ILE A 158
PHE A 189
 None
 1.39A 3mnoA-1umbB:
undetectable		 3mnoA-1umbB:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 ALA B 246
VAL B 251
LEU B 259
ALA B 321
LEU B 205
 None
 1.28A 3ozuA-1umbB:
4.5		 3ozuA-1umbB:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 GLN B  46
GLY B  43
ASP B  15
GLY B  49
ALA B  19
 None
 1.21A 3sueD-1umbB:
undetectable		 3sueD-1umbB:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		3 / 3 PRO B 309
THR B 310
LEU B 306
 None
 0.55A 3ttrA-1umbB:
undetectable		 3ttrA-1umbB:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus;
Thermus
thermophilus) 		5 / 8 GLY B  69
GLY A 155
MET B  70
GLY B  74
LEU A 163
 None
 1.06A 3v1nA-1umbB:
4.4		 3v1nA-1umbB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 9 GLY B 121
GLY B 122
SER B 132
GLY B 120
ASP B 262
 None
 1.15A 3ztvA-1umbB:
undetectable		 3ztvA-1umbB:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 9 GLY B 121
GLY B 122
SER B 132
GLY B 120
TYR B 307
 None
 1.32A 3ztvA-1umbB:
undetectable		 3ztvA-1umbB:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 HIS A  98
LEU A  51
ILE A 322
ASP A 295
ALA A  70
 None
 1.02A 4hfpD-1umbA:
undetectable		 4hfpD-1umbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 5 VAL B 115
ARG B 116
MET B 117
GLU B 172
 None
 1.46A 4hojA-1umbB:
0.0		 4hojA-1umbB:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		4 / 8 GLY A  27
ARG A 299
PHE A   8
ILE A  16
 None
 0.98A 4j4vC-1umbA:
undetectable		 4j4vC-1umbA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 5 GLU B 172
ARG B 116
PRO B 118
SER B 119
 None
 1.31A 4k17B-1umbB:
2.2		 4k17B-1umbB:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 5 LYS B 226
LEU B 224
GLU B 223
LEU B 315
 None
 1.29A 4k4yA-1umbB:
0.0		 4k4yA-1umbB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 4 LYS B 226
LEU B 224
GLU B 223
LEU B 315
 None
 1.31A 4k4yE-1umbB:
undetectable		 4k4yE-1umbB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 5 LYS B 226
LEU B 224
GLU B 223
LEU B 315
 None
 1.26A 4k4yI-1umbB:
0.0		 4k4yI-1umbB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 GLY A 174
GLY A 176
ASP A 175
ALA A 147
TYR A  95
 TDP  A1402 (-3.2A)
TDP  A1402 (-3.5A)
MG  A1401 ( 2.6A)
None
TDP  A1402 (-4.3A)
 1.06A 4lg1A-1umbA:
undetectable		 4lg1A-1umbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 GLY A 174
GLY A 176
ASP A 175
ALA A 147
TYR A  95
 TDP  A1402 (-3.2A)
TDP  A1402 (-3.5A)
MG  A1401 ( 2.6A)
None
TDP  A1402 (-4.3A)
 1.09A 4lg1C-1umbA:
undetectable		 4lg1C-1umbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE ALPHA
SUBUNIT
2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus;
Thermus
thermophilus) 		5 / 12 ALA A 154
GLY B  65
GLN B  97
ILE A 146
ALA A 177
 None
None
None
TDP  A1402 (-4.1A)
TDP  A1402 (-3.9A)
 1.02A 4r29D-1umbA:
undetectable		 4r29D-1umbA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		3 / 3 ARG B 116
TYR B 177
GLU B 172
 None
 0.60A 4zzbE-1umbB:
undetectable		 4zzbE-1umbB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		4 / 7 GLY B 122
GLY B 120
SER B 119
GLU B 216
 None
 0.86A 5izfA-1umbB:
undetectable		 5izfA-1umbB:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 10 ALA B 221
LEU B 224
ILE B 314
ALA B 317
ILE B 290
 None
 0.66A 5mvmD-1umbB:
undetectable
5mvmE-1umbB:
undetectable		 5mvmD-1umbB:
12.34
5mvmE-1umbB:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 9 LEU B 143
ILE B  81
LEU B 171
PRO B  77
ALA B  67
 None
 1.20A 5og9A-1umbB:
undetectable		 5og9A-1umbB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 12 PRO B 309
ILE B 290
ILE B 208
LEU B 205
THR B 206
 None
 1.20A 5tiwB-1umbB:
undetectable		 5tiwB-1umbB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		3 / 3 ILE B 208
VAL B 257
PRO B 289
 None
 0.68A 5uunA-1umbB:
undetectable		 5uunA-1umbB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1umb 2-OXO ACID
DEHYDROGENASE BETA
SUBUNIT
(Thermus
thermophilus) 		5 / 10 SER B 119
GLY B 120
ARG B 175
GLY B 211
LEU B 285
 None
 1.42A 6hqbA-1umbB:
undetectable
6hqbJ-1umbB:
undetectable		 6hqbA-1umbB:
12.07
6hqbJ-1umbB:
8.41