SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1umi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 TRP A 150
ALA A 183
VAL A 143
 None
 0.96A 1c4dA-1umiA:
undetectable
1c4dB-1umiA:
undetectable		 1c4dA-1umiA:
5.48
1c4dB-1umiA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 4 VAL A 293
TRP A 210
TRP A 294
 None
 1.38A 1gmkC-1umiA:
undetectable
1gmkD-1umiA:
undetectable		 1gmkC-1umiA:
5.48
1gmkD-1umiA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 8 ASP A 209
PHE A 270
LEU A 128
TRP A 140
 None
 1.00A 1rmtD-1umiA:
undetectable		 1rmtD-1umiA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.16A 3fi0D-1umiA:
undetectable		 3fi0D-1umiA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.15A 3fi0H-1umiA:
undetectable		 3fi0H-1umiA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 8 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.14A 3fi0I-1umiA:
undetectable		 3fi0I-1umiA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 9 VAL A 288
HIS A 272
ASP A 209
ILE A 254
VAL A 243
 None
 1.16A 3fi0K-1umiA:
undetectable		 3fi0K-1umiA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		5 / 10 HIS A 256
VAL A 207
PHE A 270
LEU A 223
THR A 240
 None
 1.44A 3zncA-1umiA:
undetectable		 3zncA-1umiA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 5 LEU A 188
TRP A 194
LEU A 127
ASP A 187
 None
 1.22A 4aqlA-1umiA:
undetectable		 4aqlA-1umiA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		3 / 3 HIS A 272
TRP A 179
SER A 291
 None
 1.08A 4lrhD-1umiA:
undetectable		 4lrhD-1umiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 1umi F-BOX ONLY PROTEIN 2
(Mus
musculus) 		4 / 6 ILE A 205
TYR A 261
LEU A 198
VAL A 295
 None
 0.91A 6f6jA-1umiA:
undetectable		 6f6jA-1umiA:
undetectable