SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1umr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 242
TRP C 225
 None
 1.22A 1c4dC-1umrC:
undetectable
1c4dD-1umrC:
undetectable		 1c4dC-1umrC:
10.19
1c4dD-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.34A 1c4dC-1umrC:
undetectable
1c4dD-1umrC:
undetectable		 1c4dC-1umrC:
10.19
1c4dD-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 225
TRP C 267
 None
 1.07A 2xdcA-1umrC:
undetectable
2xdcB-1umrC:
undetectable		 2xdcA-1umrC:
10.19
2xdcB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 267
TRP C 225
 None
 1.37A 2xdcA-1umrC:
undetectable
2xdcB-1umrC:
undetectable		 2xdcA-1umrC:
10.19
2xdcB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 225
VAL C 320
TRP C 267
 None
 1.37A 2xdcA-1umrC:
undetectable
2xdcB-1umrC:
undetectable		 2xdcA-1umrC:
10.19
2xdcB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.09A 2xdcA-1umrC:
undetectable
2xdcB-1umrC:
undetectable		 2xdcA-1umrC:
10.19
2xdcB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 225
TRP C 267
 None
 1.13A 2xdcC-1umrC:
undetectable
2xdcD-1umrC:
undetectable		 2xdcC-1umrC:
10.19
2xdcD-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.03A 2xdcC-1umrC:
undetectable
2xdcD-1umrC:
undetectable		 2xdcC-1umrC:
10.19
2xdcD-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.06A 2xdcE-1umrC:
undetectable
2xdcF-1umrC:
undetectable		 2xdcE-1umrC:
10.19
2xdcF-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 225
TRP C 267
 None
 1.06A 2y5mA-1umrC:
undetectable
2y5mB-1umrC:
undetectable		 2y5mA-1umrC:
10.19
2y5mB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 267
TRP C 225
 None
 1.36A 2y5mA-1umrC:
undetectable
2y5mB-1umrC:
undetectable		 2y5mA-1umrC:
10.19
2y5mB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.03A 2y5mE-1umrC:
undetectable
2y5mF-1umrC:
undetectable		 2y5mE-1umrC:
10.19
2y5mF-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 225
TRP C 267
 None
 1.06A 2y6nA-1umrC:
undetectable
2y6nB-1umrC:
undetectable		 2y6nA-1umrC:
10.19
2y6nB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 267
TRP C 225
 None
 1.37A 2y6nA-1umrC:
undetectable
2y6nB-1umrC:
undetectable		 2y6nA-1umrC:
10.19
2y6nB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 225
VAL C 320
TRP C 267
 None
 1.36A 2y6nA-1umrC:
undetectable
2y6nB-1umrC:
undetectable		 2y6nA-1umrC:
10.19
2y6nB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.07A 2y6nA-1umrC:
undetectable
2y6nB-1umrC:
undetectable		 2y6nA-1umrC:
10.19
2y6nB-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.01A 2y6nC-1umrC:
undetectable
2y6nD-1umrC:
undetectable		 2y6nC-1umrC:
10.19
2y6nD-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 320
TRP C 225
 None
 1.01A 2y6nE-1umrC:
undetectable
2y6nF-1umrC:
undetectable		 2y6nE-1umrC:
10.19
2y6nF-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 VAL C 320
TRP C 225
TRP C 267
 None
 1.06A 3zq8A-1umrC:
undetectable
3zq8B-1umrC:
undetectable		 3zq8A-1umrC:
10.19
3zq8B-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 TRP C 267
VAL C 242
TRP C 225
 None
 0.97A 3zq8C-1umrC:
undetectable
3zq8D-1umrC:
undetectable		 3zq8C-1umrC:
10.19
3zq8D-1umrC:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		4 / 4 ASN C 306
SER C 310
LEU C 309
THR C 247
 None
 1.45A 4an2A-1umrC:
undetectable		 4an2A-1umrC:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1umr CONVULXIN ALPHA
(Crotalus
durissus) 		5 / 12 HIS A  14
LYS A 130
ASP A  12
ASP A  51
ILE A  44
 None
 1.48A 4ktvA-1umrA:
0.0
4ktvB-1umrA:
0.0		 4ktvA-1umrA:
15.21
4ktvB-1umrA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1umr CONVULXIN ALPHA
(Crotalus
durissus) 		5 / 11 HIS A  14
LYS A 130
ASP A  12
ASP A  51
ILE A  44
 None
 1.35A 4ktvC-1umrA:
undetectable
4ktvD-1umrA:
undetectable		 4ktvC-1umrA:
15.21
4ktvD-1umrA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1umr CONVULXIN ALPHA
CONVULXIN BETA
(Crotalus
durissus;
Crotalus
durissus) 		3 / 3 ARG A 114
TYR C 289
GLU C 291
 None
 0.71A 4zzbE-1umrA:
undetectable		 4zzbE-1umrA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		4 / 9 ILE C 268
VAL C 254
THR C 257
TRP C 267
 None
 0.82A 5lg3I-1umrC:
undetectable		 5lg3I-1umrC:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 1umr CONVULXIN BETA
(Crotalus
durissus) 		3 / 3 GLU C 324
ARG C 213
TYR C 214
 None
 0.64A 5trqB-1umrC:
undetectable		 5trqB-1umrC:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 1umr CONVULXIN ALPHA
CONVULXIN BETA
(Crotalus
durissus) 		4 / 8 TRP C 281
THR C 285
TRP A 116
LEU A  72
 None
 1.37A 6cnjD-1umrC:
undetectable
6cnjE-1umrC:
undetectable		 6cnjD-1umrC:
23.26
6cnjE-1umrC:
19.35