SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1un1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		5 / 12 ALA A  73
TYR A  75
GLU A  85
ASP A  87
GLU A  89
 None
 0.50A 1dy4A-1un1A:
11.4		 1dy4A-1un1A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 8 TYR A  51
GLY A  49
TYR A  15
ILE A 169
 None
 0.90A 1mrjA-1un1A:
undetectable		 1mrjA-1un1A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 ASP A 269
PHE A 141
ASN A 153
 None
 0.84A 1sg9B-1un1A:
undetectable		 1sg9B-1un1A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 ILE A 139
ASP A  87
PHE A  88
 None
 0.63A 1uwjB-1un1A:
undetectable		 1uwjB-1un1A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0F_A_STRA1499_1
(CYTOCHROME P450 3A4)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 4 PHE A 141
ASP A 269
PHE A 151
VAL A 105
 None
 1.45A 1w0fA-1un1A:
0.0		 1w0fA-1un1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		5 / 12 GLN A 102
GLN A 115
ASP A 269
LEU A 101
ILE A 148
 None
 1.30A 1ynnC-1un1A:
0.0		 1ynnC-1un1A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 8 MET A 262
ARG A 268
VAL A 159
GLY A 158
 None
 0.99A 2qd3A-1un1A:
undetectable		 2qd3A-1un1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		5 / 12 VAL A 143
SER A  57
SER A 131
PHE A  90
PHE A  88
 None
 1.50A 2y04B-1un1A:
undetectable		 2y04B-1un1A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 7 GLY A  29
PHE A  74
PHE A 202
GLY A  12
 None
 0.88A 3ko0M-1un1A:
undetectable
3ko0P-1un1A:
undetectable		 3ko0M-1un1A:
17.96
3ko0P-1un1A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 7 PHE A 202
GLY A  12
GLY A  29
PHE A  74
 None
 0.96A 3ko0M-1un1A:
undetectable
3ko0P-1un1A:
undetectable		 3ko0M-1un1A:
17.96
3ko0P-1un1A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 7 ASP A  87
GLN A 115
TYR A 250
GLU A  89
 None
 1.22A 3l2vA-1un1A:
undetectable		 3l2vA-1un1A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		5 / 12 VAL A 143
SER A  57
SER A 131
PHE A  90
PHE A  88
 None
 1.37A 3nyaA-1un1A:
undetectable		 3nyaA-1un1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 ILE A 117
VAL A 243
ARG A 244
 None
 0.49A 3p73A-1un1A:
0.0		 3p73A-1un1A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		5 / 12 VAL A 143
SER A  57
SER A 131
PHE A  90
PHE A  88
 None
 1.48A 4amjA-1un1A:
undetectable		 4amjA-1un1A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		5 / 12 VAL A 143
SER A  57
SER A 131
PHE A  90
PHE A  88
 None
 1.46A 4amjB-1un1A:
undetectable		 4amjB-1un1A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 GLU A 208
TYR A  51
SER A  50
 None
 0.96A 4at0A-1un1A:
undetectable		 4at0A-1un1A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 4 ASN A 175
GLY A  69
ASP A 112
ASP A 178
 None
 1.37A 4n49A-1un1A:
undetectable		 4n49A-1un1A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 GLY A 108
GLN A 165
LYS A 160
 None
 0.84A 5imsB-1un1A:
undetectable		 5imsB-1un1A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 ASP A  87
ASN A 104
ASP A 112
 None
 0.81A 5vopA-1un1A:
undetectable		 5vopA-1un1A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 ASP A  87
ASN A 104
ASP A 112
 None
 0.83A 5vopB-1un1A:
undetectable		 5vopB-1un1A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		4 / 8 VAL A 143
ASP A 144
PRO A 123
LEU A  62
 None
 0.94A 5w3jB-1un1A:
undetectable		 5w3jB-1un1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE
(Populus
tremula) 		3 / 3 GLN A 115
TYR A 252
ASN A 251
 None
 1.02A 6dwdC-1un1A:
undetectable		 6dwdC-1un1A:
18.91