SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1un2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 1un2 THIOL-DISULFIDE
INTERCHANGE PROTEIN
(Escherichia
coli) 		4 / 5 LEU A 172
PHE A  13
VAL A  32
ALA A  26
 None
 1.16A 2cizA-1un2A:
undetectable		 2cizA-1un2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1un2 THIOL-DISULFIDE
INTERCHANGE PROTEIN
(Escherichia
coli) 		5 / 10 ALA A  26
ALA A   6
ILE A   9
LEU A 182
PHE A  13
 None
 1.14A 3fl9A-1un2A:
undetectable		 3fl9A-1un2A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1un2 THIOL-DISULFIDE
INTERCHANGE PROTEIN
(Escherichia
coli) 		3 / 3 VAL A 178
LEU A 182
VAL A  12
 None
 0.61A 4wq4A-1un2A:
undetectable		 4wq4A-1un2A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1un2 THIOL-DISULFIDE
INTERCHANGE PROTEIN
(Escherichia
coli) 		4 / 6 GLN A 164
PHE A  13
LEU A 182
PHE A 118
 None
 1.16A 5b1bC-1un2A:
undetectable
5b1bJ-1un2A:
undetectable		 5b1bC-1un2A:
19.44
5b1bJ-1un2A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 1un2 THIOL-DISULFIDE
INTERCHANGE PROTEIN
(Escherichia
coli) 		5 / 12 PHE A  13
VAL A  12
PRO A 181
GLU A 128
PHE A 116
 None
 1.35A 5f9zB-1un2A:
undetectable		 5f9zB-1un2A:
17.23