SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1unf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		5 / 11 GLY X 143
SER X 142
HIS X  43
ILE X 194
ALA X 145
 None
None
FE  X1239 (-3.3A)
None
None
 1.24A 2a58A-1unfX:
undetectable
2a58E-1unfX:
undetectable		 2a58A-1unfX:
23.58
2a58E-1unfX:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		5 / 12 ILE X 194
ALA X 145
GLY X 143
SER X 142
HIS X  43
 None
None
None
None
FE  X1239 (-3.3A)
 1.25A 2a58A-1unfX:
undetectable
2a58B-1unfX:
undetectable		 2a58A-1unfX:
23.58
2a58B-1unfX:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		5 / 12 ILE X 194
ALA X 145
GLY X 143
SER X 142
HIS X  43
 None
None
None
None
FE  X1239 (-3.3A)
 1.26A 2a58B-1unfX:
undetectable
2a58C-1unfX:
undetectable		 2a58B-1unfX:
23.58
2a58C-1unfX:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		5 / 12 ILE X 194
ALA X 145
GLY X 143
SER X 142
HIS X  95
 None
None
None
None
FE  X1239 (-3.3A)
 1.14A 2a58B-1unfX:
undetectable
2a58C-1unfX:
undetectable		 2a58B-1unfX:
23.58
2a58C-1unfX:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		5 / 11 ILE X 194
ALA X 145
GLY X 143
SER X 142
HIS X  43
 None
None
None
None
FE  X1239 (-3.3A)
 1.25A 2a58C-1unfX:
undetectable
2a58D-1unfX:
undetectable		 2a58C-1unfX:
23.58
2a58D-1unfX:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		5 / 12 ILE X 194
ALA X 145
GLY X 143
SER X 142
HIS X  43
 None
None
None
None
FE  X1239 (-3.3A)
 1.26A 2a58D-1unfX:
undetectable
2a58E-1unfX:
undetectable		 2a58D-1unfX:
23.58
2a58E-1unfX:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		3 / 3 SER X 228
ARG X 229
GLN X 232
 None
 1.01A 2xnrA-1unfX:
undetectable		 2xnrA-1unfX:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 6 ILE X  73
ASN X  94
PRO X 190
LEU X 183
 None
 1.22A 3oi8A-1unfX:
undetectable		 3oi8A-1unfX:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.31A 4v2yA-1unfX:
0.0		 4v2yA-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.36A 4v2yB-1unfX:
undetectable		 4v2yB-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.32A 4v2zA-1unfX:
0.0		 4v2zA-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 8 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.37A 4v2zB-1unfX:
0.0		 4v2zB-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.27A 4v30A-1unfX:
0.0		 4v30A-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.34A 5amiA-1unfX:
0.0		 5amiA-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 8 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.36A 5amiB-1unfX:
undetectable		 5amiB-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.32A 5amjA-1unfX:
0.0		 5amjA-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.36A 5amjB-1unfX:
0.0		 5amjB-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 5 LEU X 114
PHE X 128
LEU X 171
TRP X 223
 None
 1.29A 5m10A-1unfX:
undetectable		 5m10A-1unfX:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.35A 5oh1B-1unfX:
0.0		 5oh1B-1unfX:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.35A 5oh3A-1unfX:
0.0		 5oh3A-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 ASN X 178
PRO X 177
TRP X 197
TYR X  51
 None
 1.34A 5oh3B-1unfX:
0.0		 5oh3B-1unfX:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 THR X  39
HIS X  43
PHE X  98
MET X 102
 None
FE  X1239 (-3.3A)
None
None
 1.37A 5u6mA-1unfX:
undetectable		 5u6mA-1unfX:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1unf IRON SUPEROXIDE
DISMUTASE
(Vigna
unguiculata) 		4 / 7 THR X  39
HIS X  43
PHE X  98
MET X 102
 None
FE  X1239 (-3.3A)
None
None
 1.36A 5u6mB-1unfX:
undetectable		 5u6mB-1unfX:
19.82