SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1up2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 137
VAL A 139
TRP A 186
 None
 0.93A 1av2A-1up2A:
undetectable
1av2B-1up2A:
undetectable		 1av2A-1up2A:
6.25
1av2B-1up2A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 186
ALA A 137
VAL A 139
 None
 0.79A 1av2C-1up2A:
undetectable
1av2D-1up2A:
undetectable		 1av2C-1up2A:
6.25
1av2D-1up2A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 223
ALA A 268
VAL A 241
VAL A 203
 None
 0.90A 1epbA-1up2A:
undetectable		 1epbA-1up2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 303
ILE A 202
ASP A 244
GLY A 246
SER A 248
 None
 1.45A 1q8jA-1up2A:
7.2		 1q8jA-1up2A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 284
ILE A 202
ASP A 244
GLY A 246
SER A 248
 None
 1.29A 1q8jA-1up2A:
7.2		 1q8jA-1up2A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.90A 1rl8A-1up2A:
undetectable		 1rl8A-1up2A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.87A 1rl8B-1up2A:
undetectable		 1rl8B-1up2A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 137
VAL A 139
TRP A 186
 None
 0.90A 1w5uA-1up2A:
undetectable
1w5uB-1up2A:
undetectable		 1w5uA-1up2A:
6.25
1w5uB-1up2A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 186
ALA A 137
VAL A 139
 None
 0.88A 1w5uA-1up2A:
undetectable
1w5uB-1up2A:
undetectable		 1w5uA-1up2A:
6.25
1w5uB-1up2A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.87A 2b60A-1up2A:
undetectable		 2b60A-1up2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.88A 2b60B-1up2A:
undetectable		 2b60B-1up2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 224
ASP A 262
ASP A 217
 None
 0.72A 2igtA-1up2A:
undetectable		 2igtA-1up2A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 224
ASP A 262
ASP A 217
 None
 0.77A 2igtB-1up2A:
undetectable		 2igtB-1up2A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 137
VAL A 139
TRP A 186
 None
 0.83A 2izqA-1up2A:
undetectable
2izqB-1up2A:
undetectable		 2izqA-1up2A:
6.25
2izqB-1up2A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 186
ALA A 137
VAL A 139
 None
 0.97A 2izqC-1up2A:
undetectable
2izqD-1up2A:
undetectable		 2izqC-1up2A:
6.25
2izqD-1up2A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.86A 2nmyB-1up2A:
undetectable		 2nmyB-1up2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.88A 2nmzA-1up2A:
undetectable		 2nmzA-1up2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.88A 2rkfA-1up2A:
undetectable		 2rkfA-1up2A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 223
LEU A 251
ALA A 258
LEU A 260
 None
 0.98A 2vcvB-1up2A:
undetectable		 2vcvB-1up2A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 PHE A 223
LEU A 251
ALA A 258
LEU A 260
 None
 0.94A 2vcvK-1up2A:
undetectable		 2vcvK-1up2A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 340
TYR A 343
PHE A 271
GLY A 337
ILE A 285
 None
 1.49A 2zm7A-1up2A:
0.0		 2zm7A-1up2A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 273
ALA A 245
ALA A 290
GLY A 297
VAL A 230
 None
 1.04A 3c6gA-1up2A:
undetectable		 3c6gA-1up2A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 TRP A 186
TYR A 183
SER A 272
VAL A 241
LEU A 233
 None
 1.43A 3casA-1up2A:
4.8		 3casA-1up2A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ASP A 244
ILE A 202
ASN A 277
LEU A 273
 None
None
None
BGC  A 382 (-3.7A)
None
 0.95A 3eeyJ-1up2A:
undetectable		 3eeyJ-1up2A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
ILE A 302
ALA A 290
ILE A 291
 None
 0.78A 3ekwB-1up2A:
undetectable		 3ekwB-1up2A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 246
ALA A 245
VAL A 301
ALA A 290
ILE A 291
 None
 0.88A 3ekwB-1up2A:
undetectable		 3ekwB-1up2A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 6 VAL A 143
LEU A  91
ILE A 346
ALA A 199
LEU A 194
 None
 1.39A 3kk6B-1up2A:
undetectable		 3kk6B-1up2A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 TRP A 186
ALA A 137
VAL A 139
 None
 1.01A 3l8lA-1up2A:
undetectable
3l8lB-1up2A:
undetectable		 3l8lA-1up2A:
6.25
3l8lB-1up2A:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 ASP A 244
SER A 272
VAL A 275
THR A 160
TYR A 162
 None
None
None
None
IFM  A 383 (-4.3A)
 1.41A 3mbhA-1up2A:
2.2		 3mbhA-1up2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 244
SER A 272
VAL A 275
THR A 160
TYR A 162
 None
None
None
None
IFM  A 383 (-4.3A)
 1.39A 3mbhB-1up2A:
2.1		 3mbhB-1up2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 244
SER A 272
VAL A 275
THR A 160
TYR A 162
 None
None
None
None
IFM  A 383 (-4.3A)
 1.39A 3mbhC-1up2A:
2.1		 3mbhC-1up2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 244
SER A 272
VAL A 275
THR A 160
TYR A 162
 None
None
None
None
IFM  A 383 (-4.3A)
 1.39A 3mbhD-1up2A:
3.4		 3mbhD-1up2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 244
SER A 272
VAL A 275
THR A 160
TYR A 162
 None
None
None
None
IFM  A 383 (-4.3A)
 1.36A 3mbhE-1up2A:
undetectable		 3mbhE-1up2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 ASP A 244
SER A 272
VAL A 275
THR A 160
TYR A 162
 None
None
None
None
IFM  A 383 (-4.3A)
 1.38A 3mbhF-1up2A:
3.2		 3mbhF-1up2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 268
SER A 298
SER A 292
VAL A 226
TYR A 242
 None
 1.31A 3qxvE-1up2A:
undetectable		 3qxvE-1up2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 284
ASP A 303
ILE A 202
GLY A 246
SER A 248
 None
 1.41A 4djfB-1up2A:
7.4		 4djfB-1up2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 ALA A 371
PHE A 366
ALA A 107
ALA A 122
 None
None
None
MHO  A 105 ( 3.6A)
 0.94A 4du2A-1up2A:
undetectable		 4du2A-1up2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 231
ARG A 267
ASP A 224
 None
 0.90A 4fp9C-1up2A:
undetectable		 4fp9C-1up2A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 231
ARG A 267
ASP A 224
 None
 0.88A 4fp9F-1up2A:
undetectable		 4fp9F-1up2A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 PRO A 157
TYR A 146
GLY A 148
 None
 0.63A 4g2zA-1up2A:
undetectable		 4g2zA-1up2A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 201
ALA A 240
LEU A  91
PRO A 331
ILE A 202
 None
 1.18A 4g8zX-1up2A:
undetectable		 4g8zX-1up2A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 219
ASP A 224
ASP A 231
 None
 0.87A 4kicB-1up2A:
undetectable		 4kicB-1up2A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  91
TYR A 242
ILE A 346
SER A 272
PHE A  96
 None
 1.47A 4lhmA-1up2A:
undetectable		 4lhmA-1up2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 ASN A 307
GLU A 283
TYR A 279
ARG A 249
 None
None
None
SO4  A 386 (-3.0A)
 1.12A 4mi4B-1up2A:
undetectable
4mi4C-1up2A:
undetectable		 4mi4B-1up2A:
17.61
4mi4C-1up2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 307
GLU A 283
TYR A 279
ARG A 249
 None
None
None
SO4  A 386 (-3.0A)
 1.11A 4mj8B-1up2A:
undetectable
4mj8C-1up2A:
undetectable		 4mj8B-1up2A:
17.83
4mj8C-1up2A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 SER A 292
LEU A 208
MET A 256
 None
 0.77A 5ikrB-1up2A:
undetectable		 5ikrB-1up2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 THR A 332
ALA A 329
THR A 304
ALA A 334
ASP A 282
 None
 1.22A 5lf3V-1up2A:
undetectable
5lf3W-1up2A:
undetectable		 5lf3V-1up2A:
22.22
5lf3W-1up2A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 358
PRO A 322
TYR A 172
 None
None
SO4  A 385 (-4.8A)
 0.94A 5tzoB-1up2A:
undetectable		 5tzoB-1up2A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1up2 CELA1 PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 338
PHE A 271
SER A 298
GLY A 288
 None
 0.96A 5v0vA-1up2A:
undetectable		 5v0vA-1up2A:
19.66