SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  91
VAL A  32
VAL A  30
LEU A 108
 None
 0.91A 1igxA-1uqxA:
undetectable		 1igxA-1uqxA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 6 VAL A  36
GLN A  53
GLY A  15
LEU A 112
 None
 0.98A 3bjwE-1uqxA:
undetectable		 3bjwE-1uqxA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 5 VAL A  32
ASP A  33
PHE A  14
GLY A  60
 None
 1.22A 4xp6A-1uqxA:
undetectable		 4xp6A-1uqxA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 6 VAL A  30
ALA A  38
GLN A  53
VAL A  16
 None
 0.91A 5i8fA-1uqxA:
undetectable		 5i8fA-1uqxA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 ASN A  24
ALA A  23
GLN A  26
SER A  43
 MMA  A1116 (-3.8A)
MMA  A1116 (-3.4A)
None
None
 0.89A 5km8A-1uqxA:
undetectable
5km8B-1uqxA:
undetectable		 5km8A-1uqxA:
24.52
5km8B-1uqxA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  32
GLY A  15
LEU A 108
THR A  17
 None
 1.01A 5sxqA-1uqxA:
undetectable		 5sxqA-1uqxA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  32
GLY A  15
LEU A 108
THR A  17
 None
 1.00A 5sxqB-1uqxA:
undetectable		 5sxqB-1uqxA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  32
GLY A  15
LEU A 108
THR A  17
 None
 0.98A 5sxtA-1uqxA:
undetectable		 5sxtA-1uqxA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  32
GLY A  15
LEU A 108
THR A  17
 None
 0.97A 5sxtB-1uqxA:
undetectable		 5sxtB-1uqxA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  32
GLY A  15
LEU A 108
THR A  17
 None
 1.00A 5syjA-1uqxA:
undetectable		 5syjA-1uqxA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1uqx LECTIN
(Ralstonia
solanacearum) 		4 / 8 VAL A  32
GLY A  15
LEU A 108
THR A  17
 None
 0.97A 5syjB-1uqxA:
undetectable		 5syjB-1uqxA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 1uqx LECTIN
(Ralstonia
solanacearum) 		5 / 12 ALA A  22
ASN A  69
GLY A  44
SER A  43
GLY A  42
 MMA  A1116 (-3.3A)
None
None
None
None
 1.14A 6c79A-1uqxA:
undetectable		 6c79A-1uqxA:
24.14