SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ur1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 9 ILE A 230
GLY A 229
ASN A 198
LEU A 263
ASP A 153
 None
 1.38A 1dgmA-1ur1A:
2.5		 1dgmA-1ur1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 9 PHE A  61
GLY A 329
LEU A 356
LEU A  56
PHE A 352
 None
 1.08A 1nr6A-1ur1A:
undetectable		 1nr6A-1ur1A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 12 LEU A 314
LEU A 263
ILE A 230
GLY A 232
LEU A 234
 None
 0.88A 2ouzA-1ur1A:
undetectable		 2ouzA-1ur1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 12 LEU A 365
LEU A 263
ILE A 230
GLY A 232
LEU A 234
 None
 1.08A 2ouzA-1ur1A:
undetectable		 2ouzA-1ur1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_0
(DIHYDROFOLATE
REDUCTASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 12 ILE A 241
LEU A 263
PHE A 312
ILE A 322
ASN A  34
 None
 1.05A 2w3bB-1ur1A:
undetectable		 2w3bB-1ur1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 12 ILE A 241
LEU A 263
PHE A 312
ILE A 322
ASN A  34
 None
 1.04A 2w3mA-1ur1A:
undetectable		 2w3mA-1ur1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 VAL A 265
TRP A 328
TRP A 336
 None
XYS  A1376 ( 4.1A)
XYS  A1376 ( 3.9A)
 1.33A 2xdcA-1ur1A:
undetectable
2xdcB-1ur1A:
undetectable		 2xdcA-1ur1A:
5.46
2xdcB-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 TRP A 336
VAL A 265
TRP A 328
 XYS  A1376 ( 3.9A)
None
XYS  A1376 ( 4.1A)
 1.34A 2xdcA-1ur1A:
undetectable
2xdcB-1ur1A:
undetectable		 2xdcA-1ur1A:
5.46
2xdcB-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 VAL A 265
TRP A 328
TRP A 336
 None
XYS  A1376 ( 4.1A)
XYS  A1376 ( 3.9A)
 1.43A 2xdcC-1ur1A:
undetectable
2xdcD-1ur1A:
undetectable		 2xdcC-1ur1A:
5.46
2xdcD-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 VAL A 265
TRP A 328
TRP A 336
 None
XYS  A1376 ( 4.1A)
XYS  A1376 ( 3.9A)
 1.34A 2y5mA-1ur1A:
undetectable
2y5mB-1ur1A:
undetectable		 2y5mA-1ur1A:
5.46
2y5mB-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 VAL A 265
TRP A 328
TRP A 336
 None
XYS  A1376 ( 4.1A)
XYS  A1376 ( 3.9A)
 1.33A 2y6nA-1ur1A:
undetectable
2y6nB-1ur1A:
undetectable		 2y6nA-1ur1A:
5.46
2y6nB-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 TRP A 336
VAL A 265
TRP A 328
 XYS  A1376 ( 3.9A)
None
XYS  A1376 ( 4.1A)
 1.33A 2y6nA-1ur1A:
undetectable
2y6nB-1ur1A:
undetectable		 2y6nA-1ur1A:
5.46
2y6nB-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 11 ALA A  39
ASN A  54
LEU A  99
PHE A  90
THR A 326
 None
 1.33A 3fl9C-1ur1A:
undetectable		 3fl9C-1ur1A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 10 GLY A 227
PHE A 183
LEU A 228
LEU A 256
ILE A 215
 None
 1.19A 3kvrB-1ur1A:
undetectable		 3kvrB-1ur1A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 12 GLY A 229
VAL A 154
ASP A 153
SER A 262
ALA A  39
 None
None
None
XYS  A1376 (-3.4A)
None
 1.02A 3sufD-1ur1A:
undetectable		 3sufD-1ur1A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 6 GLY A  38
VAL A 102
HIS A 100
SER A  63
THR A  65
 None
 0.97A 3tj7A-1ur1A:
undetectable
3tj7B-1ur1A:
undetectable		 3tj7A-1ur1A:
20.22
3tj7B-1ur1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 6 GLY A  38
VAL A 102
HIS A 100
SER A  63
THR A  65
 None
 0.97A 3tj7C-1ur1A:
undetectable
3tj7D-1ur1A:
undetectable		 3tj7C-1ur1A:
20.22
3tj7D-1ur1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 6 VAL A 102
HIS A 100
SER A  63
THR A  65
GLY A  38
 None
 0.96A 3tj7C-1ur1A:
undetectable
3tj7D-1ur1A:
undetectable		 3tj7C-1ur1A:
20.22
3tj7D-1ur1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 ASP A 199
GLY A 160
TYR A 200
 None
 0.80A 3w9tC-1ur1A:
undetectable		 3w9tC-1ur1A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 ASP A 199
GLY A 160
TYR A 200
 None
 0.81A 3w9tG-1ur1A:
undetectable		 3w9tG-1ur1A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 VAL A 265
TRP A 328
TRP A 336
 None
XYS  A1376 ( 4.1A)
XYS  A1376 ( 3.9A)
 1.29A 3zq8A-1ur1A:
undetectable
3zq8B-1ur1A:
undetectable		 3zq8A-1ur1A:
5.46
3zq8B-1ur1A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 12 ILE A 241
LEU A 263
PHE A 312
ILE A 322
ASN A  34
 None
 1.05A 4kebB-1ur1A:
undetectable		 4kebB-1ur1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 5 THR A 346
THR A 293
ASP A 290
TYR A 285
 None
 0.97A 4oltA-1ur1A:
undetectable		 4oltA-1ur1A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 5 THR A 346
THR A 293
ASP A 290
TYR A 285
 None
 0.91A 4oltB-1ur1A:
undetectable		 4oltB-1ur1A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 5 THR A 346
THR A 293
ASP A 290
TYR A 285
 None
 0.94A 4qwpA-1ur1A:
undetectable		 4qwpA-1ur1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 5 THR A 346
THR A 293
ASP A 290
TYR A 285
 None
 0.98A 4qwpB-1ur1A:
0.0		 4qwpB-1ur1A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		5 / 11 LEU A  56
PHE A  93
LEU A  41
GLY A  48
SER A 331
 None
 1.21A 4zbqA-1ur1A:
undetectable		 4zbqA-1ur1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 7 ILE A 322
PHE A 315
VAL A 258
ILE A 230
 None
 0.83A 4zzbC-1ur1A:
undetectable
4zzbD-1ur1A:
undetectable		 4zzbC-1ur1A:
21.32
4zzbD-1ur1A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 8 ILE A 236
GLY A 235
ASN A 347
ASP A 264
 None
 0.94A 5hieD-1ur1A:
undetectable		 5hieD-1ur1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 5 PHE A 183
ILE A 179
MET A 223
GLN A 219
 None
 1.37A 5jm4A-1ur1A:
undetectable		 5jm4A-1ur1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		3 / 3 THR A  65
MET A 101
HIS A 100
 None
 0.89A 5uunA-1ur1A:
undetectable		 5uunA-1ur1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 1ur1 ENDOXYLANASE
(Cellvibrio
mixtus) 		4 / 5 HIS A 259
ASP A 323
HIS A 194
ARG A 257
 None
 1.34A 6dchA-1ur1A:
undetectable		 6dchA-1ur1A:
23.96