SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ur4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 9 GLU A  38
VAL A 327
TRP A 324
GLY A 346
GLY A 366
 None
 1.32A 1bcuH-1ur4A:
undetectable		 1bcuH-1ur4A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 9 SER A  39
VAL A 327
TRP A 324
GLY A 346
GLY A 366
 None
 1.01A 1bcuH-1ur4A:
undetectable		 1bcuH-1ur4A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 ARG A 191
VAL A 190
SER A 187
ASN A 184
 None
 1.02A 1hwiB-1ur4A:
undetectable		 1hwiB-1ur4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 ARG A 191
VAL A 190
SER A 187
ASN A 184
 None
 1.02A 1hwiC-1ur4A:
undetectable		 1hwiC-1ur4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 ARG A 191
VAL A 190
SER A 187
ASN A 184
 None
 1.02A 1hwiD-1ur4A:
undetectable		 1hwiD-1ur4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 ARG A 191
VAL A 190
SER A 187
ASN A 184
 None
 0.95A 1hwkA-1ur4A:
undetectable		 1hwkA-1ur4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 ARG A 191
VAL A 190
SER A 187
ASN A 184
 None
 0.97A 1hwkC-1ur4A:
undetectable		 1hwkC-1ur4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 ARG A 191
VAL A 190
SER A 187
ASN A 184
 None
 0.97A 1hwkD-1ur4A:
undetectable		 1hwkD-1ur4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 ALA A 360
TRP A 347
GLU A 321
ARG A  68
TRP A  70
 None
B2G  A1399 (-3.7A)
None
None
None
 1.48A 1lf9B-1ur4A:
undetectable		 1lf9B-1ur4A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 ASP A 108
ASP A  29
SER A 232
THR A 204
 None
 0.79A 1m4iA-1ur4A:
undetectable		 1m4iA-1ur4A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 ILE A 157
ILE A 155
THR A 193
 None
 0.59A 1rg7A-1ur4A:
undetectable		 1rg7A-1ur4A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 SER A 367
VAL A  41
LEU A  36
 None
 0.74A 1yajG-1ur4A:
1.7		 1yajG-1ur4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 6 ASP A 376
PHE A 377
THR A 269
GLU A 271
 None
 1.35A 2dttB-1ur4A:
0.0
2dttC-1ur4A:
0.0		 2dttB-1ur4A:
12.75
2dttC-1ur4A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 9 VAL A 261
THR A 264
VAL A 300
ILE A 304
VAL A 303
 None
 1.38A 2l8mA-1ur4A:
undetectable		 2l8mA-1ur4A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.76A 2v2gA-1ur4A:
undetectable
2v2gB-1ur4A:
undetectable		 2v2gA-1ur4A:
21.04
2v2gB-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.76A 2v2gA-1ur4A:
undetectable
2v2gB-1ur4A:
undetectable		 2v2gA-1ur4A:
21.04
2v2gB-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.76A 2v2gC-1ur4A:
undetectable
2v2gD-1ur4A:
undetectable		 2v2gC-1ur4A:
21.04
2v2gD-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.75A 2v2gC-1ur4A:
undetectable
2v2gD-1ur4A:
undetectable		 2v2gC-1ur4A:
21.04
2v2gD-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
ALA A 213
 None
 0.83A 2v32A-1ur4A:
undetectable
2v32B-1ur4A:
undetectable		 2v32A-1ur4A:
21.04
2v32B-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.78A 2v32A-1ur4A:
undetectable
2v32B-1ur4A:
undetectable		 2v32A-1ur4A:
21.04
2v32B-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
ALA A 213
 None
 0.90A 2v32A-1ur4A:
undetectable
2v32B-1ur4A:
undetectable		 2v32A-1ur4A:
21.04
2v32B-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.79A 2v32A-1ur4A:
undetectable
2v32B-1ur4A:
undetectable		 2v32A-1ur4A:
21.04
2v32B-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.77A 2v32C-1ur4A:
undetectable
2v32D-1ur4A:
undetectable		 2v32C-1ur4A:
21.04
2v32D-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.78A 2v32C-1ur4A:
undetectable
2v32D-1ur4A:
undetectable		 2v32C-1ur4A:
21.04
2v32D-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.68A 2v41C-1ur4A:
undetectable
2v41D-1ur4A:
undetectable		 2v41C-1ur4A:
21.04
2v41D-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.79A 2v41C-1ur4A:
undetectable
2v41D-1ur4A:
undetectable		 2v41C-1ur4A:
21.04
2v41D-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.74A 2v41E-1ur4A:
undetectable
2v41F-1ur4A:
undetectable		 2v41E-1ur4A:
21.04
2v41F-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.68A 2v41E-1ur4A:
undetectable
2v41F-1ur4A:
undetectable		 2v41E-1ur4A:
21.04
2v41F-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.89A 2v41G-1ur4A:
undetectable
2v41H-1ur4A:
undetectable		 2v41G-1ur4A:
21.04
2v41H-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 THR A 254
VAL A 251
SER A 250
GLU A 217
 None
 0.73A 2v41G-1ur4A:
undetectable
2v41H-1ur4A:
undetectable		 2v41G-1ur4A:
21.04
2v41H-1ur4A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 LEU A 198
TYR A 233
TYR A 212
ALA A 262
GLU A 263
 None
 1.50A 2vdmA-1ur4A:
0.0
2vdmB-1ur4A:
undetectable		 2vdmA-1ur4A:
23.61
2vdmB-1ur4A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		6 / 12 SER A  39
VAL A 327
TRP A 324
GLY A 346
GLY A  82
GLY A 366
 None
 1.25A 2w26A-1ur4A:
undetectable		 2w26A-1ur4A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 4 GLY A  84
GLY A  82
GLY A  80
GLY A 344
 None
 0.68A 3bogD-1ur4A:
0.0		 3bogD-1ur4A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 HIS A 276
GLY A 277
TRP A 347
PHE A 364
 B2G  A1399 ( 3.8A)
CA  A1398 ( 4.8A)
B2G  A1399 (-3.7A)
None
 1.19A 3ccfA-1ur4A:
undetectable		 3ccfA-1ur4A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLN A 372
ASP A 272
GLY A 275
ASP A 274
SER A 345
 None
CA  A1398 (-3.0A)
None
CA  A1398 (-3.0A)
None
 1.22A 3d91A-1ur4A:
undetectable		 3d91A-1ur4A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 6 TYR A  64
GLY A 316
MET A 260
ASN A  63
 None
 1.09A 3e9rA-1ur4A:
undetectable		 3e9rA-1ur4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 6 TYR A  64
GLY A 316
MET A 260
ASN A  63
 None
 1.07A 3e9rC-1ur4A:
undetectable		 3e9rC-1ur4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 GLU A  46
SER A 384
VAL A 293
 None
 0.81A 3eeoA-1ur4A:
undetectable		 3eeoA-1ur4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 HIS A 276
GLY A  83
GLY A  82
SER A 112
ASP A 359
 B2G  A1399 ( 3.8A)
None
None
None
B2G  A1399 (-3.0A)
 1.20A 3i5uB-1ur4A:
undetectable		 3i5uB-1ur4A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 LEU A  57
THR A  56
ALA A  42
ILE A 325
 None
 0.84A 3jusA-1ur4A:
undetectable		 3jusA-1ur4A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 LEU A  57
THR A  56
ALA A  42
ILE A 325
 None
 0.84A 3jusA-1ur4A:
undetectable		 3jusA-1ur4A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_B_TPFB490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 9 TYR A 142
TYR A 111
ALA A 185
ALA A 189
THR A 193
 None
None
PEG  A1397 (-3.6A)
None
None
 1.39A 3l4dB-1ur4A:
undetectable		 3l4dB-1ur4A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		6 / 12 ALA A  98
THR A  99
ALA A 100
VAL A  65
ALA A  91
ASP A  52
 None
 1.17A 3mg0Y-1ur4A:
undetectable
3mg0Z-1ur4A:
undetectable		 3mg0Y-1ur4A:
19.70
3mg0Z-1ur4A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 TYR A 142
ASP A 113
ASP A  75
 None
 0.83A 3ou6B-1ur4A:
undetectable		 3ou6B-1ur4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3G_A_TLTA317_1
(ALDOSE REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 7 TRP A 320
HIS A 110
TRP A  70
TRP A 324
 None
 1.14A 3s3gA-1ur4A:
2.2		 3s3gA-1ur4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 5 ILE A 215
THR A 204
SER A 231
PHE A 229
 None
 1.07A 3snfA-1ur4A:
undetectable		 3snfA-1ur4A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 TRP A 320
HIS A 110
TRP A  70
TRP A 324
 None
 1.12A 3v35A-1ur4A:
7.2		 3v35A-1ur4A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A 256
ASP A 227
ALA A 313
VAL A 259
PHE A 229
 None
 1.10A 4dx5B-1ur4A:
undetectable		 4dx5B-1ur4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 ARG A 211
TRP A 176
GLY A 168
 None
 0.77A 4e7cA-1ur4A:
undetectable		 4e7cA-1ur4A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A 314
GLY A 311
VAL A 307
LEU A 248
VAL A 228
 None
 0.93A 4f84A-1ur4A:
undetectable		 4f84A-1ur4A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 PRO A 118
ASN A 205
HIS A 238
 None
 1.01A 4ma3H-1ur4A:
0.0
4ma3L-1ur4A:
undetectable		 4ma3H-1ur4A:
21.27
4ma3L-1ur4A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 4 ASN A 336
GLY A 328
ASP A  29
ASP A 370
 None
None
None
CA  A1398 (-2.9A)
 1.16A 4n49A-1ur4A:
undetectable		 4n49A-1ur4A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 ALA A 149
LEU A 147
ALA A 107
ILE A  69
ALA A  91
 None
 0.92A 4o2bD-1ur4A:
3.1		 4o2bD-1ur4A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A 366
GLY A 365
GLY A  82
ALA A 348
ILE A  34
 None
 1.01A 4rtmA-1ur4A:
undetectable		 4rtmA-1ur4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A 256
ASP A 227
ALA A 313
VAL A 259
PHE A 229
 None
 1.09A 4u8yB-1ur4A:
undetectable		 4u8yB-1ur4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A 256
ASP A 227
ALA A 313
VAL A 259
PHE A 229
 None
 1.12A 4u95B-1ur4A:
undetectable		 4u95B-1ur4A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 11 ALA A 138
LEU A 139
TYR A 142
GLU A 173
LEU A 170
 None
 0.95A 4wg0C-1ur4A:
undetectable
4wg0D-1ur4A:
undetectable
4wg0E-1ur4A:
undetectable		 4wg0C-1ur4A:
3.64
4wg0D-1ur4A:
3.64
4wg0E-1ur4A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A  19
LEU A  20
ASP A 302
VAL A 317
PHE A  24
 None
 1.17A 4wnwA-1ur4A:
undetectable		 4wnwA-1ur4A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 THR A 193
HIS A 202
LEU A 106
 None
 0.73A 5axdA-1ur4A:
undetectable		 5axdA-1ur4A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 THR A 193
HIS A 202
LEU A 106
 None
 0.74A 5axdC-1ur4A:
undetectable		 5axdC-1ur4A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 ALA A 149
LEU A 147
ALA A 107
ILE A  69
ALA A  91
 None
 0.84A 5eypB-1ur4A:
3.0		 5eypB-1ur4A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		3 / 3 LYS A  22
ASP A 392
ILE A 315
 None
 0.89A 5kc4E-1ur4A:
0.0		 5kc4E-1ur4A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 GLY A 158
PHE A 318
ILE A  94
ALA A  98
VAL A  67
 None
 1.12A 5n0xA-1ur4A:
undetectable		 5n0xA-1ur4A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 ALA A 149
LEU A 147
ALA A 107
ILE A  69
ALA A  91
 None
 0.77A 5xiwB-1ur4A:
2.8		 5xiwB-1ur4A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		5 / 12 ALA A 149
LEU A 147
ALA A 107
ILE A  69
ALA A  91
 None
 0.69A 5xiwD-1ur4A:
2.9		 5xiwD-1ur4A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ur4 GALACTANASE
(Bacillus
licheniformis) 		4 / 8 GLU A 271
PHE A 375
PHE A  43
LEU A  57
 None
 1.04A 5y2tB-1ur4A:
undetectable		 5y2tB-1ur4A:
undetectable