SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1urd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 GLU A 103
ALA A 101
VAL A 129
MET A 106
 None
 0.76A 1a29A-1urdA:
undetectable		 1a29A-1urdA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 GLN A 141
ILE A 288
PHE A  73
PHE A 180
 MLR  A1400 (-3.1A)
None
MLR  A1400 (-4.6A)
None
 1.14A 1e71M-1urdA:
undetectable		 1e71M-1urdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 GLN A 141
ILE A 288
PHE A  73
PHE A 180
 MLR  A1400 (-3.1A)
None
MLR  A1400 (-4.6A)
None
 1.17A 1e72M-1urdA:
undetectable		 1e72M-1urdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 6 GLN A 141
ILE A 288
PHE A  73
PHE A 180
 MLR  A1400 (-3.1A)
None
MLR  A1400 (-4.6A)
None
 1.14A 1e73M-1urdA:
0.0		 1e73M-1urdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 6 LEU A 309
VAL A  34
SER A  36
GLN A  38
 None
None
None
MLR  A1400 (-3.0A)
 1.01A 1e7aB-1urdA:
0.9		 1e7aB-1urdA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 ALA A 377
ILE A 376
GLN A 373
ILE A 237
MET A 172
 None
 1.03A 1xozA-1urdA:
undetectable		 1xozA-1urdA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 11 GLN A 315
ALA A 314
GLY A  91
THR A 289
ALA A 290
 None
 1.14A 2f16H-1urdA:
undetectable
2f16I-1urdA:
undetectable		 2f16H-1urdA:
20.70
2f16I-1urdA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 11 GLN A 315
ALA A 314
GLY A  91
THR A 289
ALA A 290
 None
 1.13A 2f16V-1urdA:
undetectable
2f16W-1urdA:
undetectable		 2f16V-1urdA:
20.70
2f16W-1urdA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 6 TYR A 182
TYR A 191
GLN A 394
ILE A 393
 None
 1.36A 2pgzD-1urdA:
undetectable
2pgzE-1urdA:
undetectable		 2pgzD-1urdA:
18.59
2pgzE-1urdA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 ILE A 376
PHE A 171
PHE A 162
ALA A 281
TYR A 173
 None
 1.43A 3apwA-1urdA:
undetectable		 3apwA-1urdA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 ILE A 376
PHE A 171
PHE A 162
ALA A 281
TYR A 173
 None
 1.44A 3apwB-1urdA:
undetectable		 3apwB-1urdA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 SER A 296
ALA A 301
LEU A 305
THR A 298
 None
 0.94A 3cfqA-1urdA:
undetectable
3cfqB-1urdA:
undetectable		 3cfqA-1urdA:
14.99
3cfqB-1urdA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 PRO A 271
ILE A 145
PRO A 156
TYR A 147
 None
 1.39A 3d9lA-1urdA:
undetectable
3d9lY-1urdA:
undetectable		 3d9lA-1urdA:
14.59
3d9lY-1urdA:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 ASP A 208
ILE A 393
TYR A 191
ILE A 359
LEU A 178
 None
 1.24A 4a84A-1urdA:
undetectable		 4a84A-1urdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 LEU A 350
PHE A 346
VAL A 142
ALA A 120
THR A 123
 None
 1.19A 4fiaA-1urdA:
undetectable		 4fiaA-1urdA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 12 LEU A 350
PHE A 346
VAL A 142
ALA A 120
THR A 123
 None
 1.19A 4fiaA-1urdA:
undetectable		 4fiaA-1urdA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 ALA A 301
LEU A 305
THR A 298
SER A 296
 None
 1.00A 4ikjA-1urdA:
undetectable
4ikjB-1urdA:
undetectable		 4ikjA-1urdA:
16.53
4ikjB-1urdA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 SER A 296
ALA A 301
LEU A 305
THR A 298
 None
 0.96A 4ikjA-1urdA:
undetectable
4ikjB-1urdA:
undetectable		 4ikjA-1urdA:
16.53
4ikjB-1urdA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 SER A 296
ALA A 301
LEU A 305
THR A 298
 None
 0.96A 4ikkA-1urdA:
undetectable
4ikkB-1urdA:
undetectable		 4ikkA-1urdA:
16.53
4ikkB-1urdA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 ALA A 301
LEU A 305
THR A 298
SER A 296
 None
 0.99A 4iklA-1urdA:
undetectable
4iklB-1urdA:
undetectable		 4iklA-1urdA:
16.53
4iklB-1urdA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		3 / 3 TYR A  76
GLY A  85
PRO A  86
 None
 0.67A 4qwpA-1urdA:
undetectable		 4qwpA-1urdA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 LEU A 372
LEU A 207
ASN A 392
ILE A 393
 None
 0.81A 4rmjA-1urdA:
undetectable		 4rmjA-1urdA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 ASN A  69
PHE A  75
TRP A  37
TRP A  35
 None
 1.16A 4v2zC-1urdA:
undetectable		 4v2zC-1urdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 4 ASN A 392
SER A 370
ALA A 368
VAL A 365
 None
 1.29A 4x1kC-1urdA:
undetectable		 4x1kC-1urdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 5 LEU A 372
ALA A 386
VAL A 192
ILE A 205
 None
 0.95A 4xe3B-1urdA:
undetectable		 4xe3B-1urdA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		5 / 10 ASP A  87
VAL A  88
LEU A 309
THR A 310
ALA A 308
 None
 1.11A 4yhaB-1urdA:
undetectable		 4yhaB-1urdA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 8 ASN A  69
PHE A  75
TRP A  37
TRP A  35
 None
 1.02A 5amkA-1urdA:
undetectable		 5amkA-1urdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 PHE A 343
THR A 123
ILE A 325
VAL A 140
 None
 0.81A 5ik1A-1urdA:
undetectable		 5ik1A-1urdA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1urd MALTOSE-BINDING
PROTEIN
(Alicyclobacillus
acidocaldarius) 		4 / 7 GLY A 235
LYS A 239
ALA A 240
ASP A 256
 None
 0.95A 5mvsA-1urdA:
undetectable		 5mvsA-1urdA:
18.88