SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1urx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		5 / 12 ASP A  46
ASP A  22
ASP A 279
GLY A  90
ALA A  60
 None
CA  A1300 (-3.0A)
CA  A1300 (-3.3A)
None
None
 0.80A 3n3iA-1urxA:
undetectable		 3n3iA-1urxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		4 / 6 THR A  79
ASN A 107
GLY A 108
ILE A 250
 None
 1.01A 3w9tF-1urxA:
undetectable		 3w9tF-1urxA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		4 / 6 TYR A  50
ASP A  22
GLN A  21
GLU A 123
 None
CA  A1300 (-3.0A)
None
None
 1.28A 4azvA-1urxA:
undetectable		 4azvA-1urxA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		5 / 12 VAL A 283
GLU A 123
GLY A 206
TYR A 208
ILE A 219
 None
 1.24A 4xucA-1urxA:
undetectable		 4xucA-1urxA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		5 / 12 VAL A 283
GLU A 123
GLY A 206
TYR A 208
ILE A 219
 None
 1.25A 4xudA-1urxA:
undetectable		 4xudA-1urxA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		3 / 3 ARG A 204
TYR A 121
GLU A 123
 None
 0.64A 4zzbE-1urxA:
undetectable		 4zzbE-1urxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		5 / 10 ILE A 116
ILE A 249
VAL A 120
TRP A 138
ILE A 148
 None
None
None
GLA  A1292 ( 3.4A)
None
 1.30A 5lg3F-1urxA:
undetectable		 5lg3F-1urxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		3 / 3 TYR A 106
PRO A  99
LEU A 268
 AAL  A1293 ( 3.9A)
None
None
 0.91A 6beoA-1urxA:
undetectable		 6beoA-1urxA:
3.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_D8ZA831_0
(GEPHYRIN)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		5 / 11 ASP A 252
PHE A 276
ILE A  95
TYR A 154
MET A 167
 GLA  A1292 ( 4.2A)
None
None
None
None
 1.35A 6fgdA-1urxA:
undetectable		 6fgdA-1urxA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		3 / 3 TYR A 182
ASP A 181
GLN A 183
 None
GLA  A1292 ( 4.8A)
None
 0.89A 6g1pA-1urxA:
undetectable		 6g1pA-1urxA:
20.89