SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1usv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 499
LYS A 426
LEU A 479
GLY A 476
PHE A 510
 None
 1.46A 1d4fC-1usvA:
undetectable		 1d4fC-1usvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 499
LYS A 426
LEU A 479
GLY A 476
PHE A 510
 None
 1.38A 1d4fD-1usvA:
undetectable		 1d4fD-1usvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 5 SER B  49
THR B  72
GLU B  51
GLY B  52
 None
 1.10A 1icrA-1usvB:
undetectable
1icrB-1usvB:
undetectable		 1icrA-1usvB:
18.83
1icrB-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 5 GLU B  51
GLY B  52
SER B  49
THR B  72
 None
 1.11A 1icrA-1usvB:
undetectable
1icrB-1usvB:
undetectable		 1icrA-1usvB:
18.83
1icrB-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 6 SER B  49
THR B  72
GLU B  51
GLY B  52
 None
 1.14A 1icuA-1usvB:
undetectable
1icuB-1usvB:
undetectable		 1icuA-1usvB:
18.83
1icuB-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 6 GLU B  51
GLY B  52
SER B  49
THR B  72
 None
 1.12A 1icuA-1usvB:
undetectable
1icuB-1usvB:
undetectable		 1icuA-1usvB:
18.83
1icuB-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 6 SER B  49
THR B  72
GLU B  51
GLY B  52
 None
 1.08A 1icuC-1usvB:
undetectable
1icuD-1usvB:
undetectable		 1icuC-1usvB:
18.83
1icuD-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 5 SER B  49
THR B  72
GLU B  51
GLY B  52
 None
 1.10A 1icvC-1usvB:
undetectable
1icvD-1usvB:
undetectable		 1icvC-1usvB:
18.83
1icvD-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 5 GLU B  51
GLY B  52
SER B  49
THR B  72
 None
 1.09A 1icvC-1usvB:
undetectable
1icvD-1usvB:
undetectable		 1icvC-1usvB:
18.83
1icvD-1usvB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 5 GLU B  51
GLY B  52
SER B  49
THR B  72
 None
 1.12A 1kqbA-1usvB:
undetectable
1kqbB-1usvB:
undetectable		 1kqbA-1usvB:
19.40
1kqbB-1usvB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 6 SER B  49
THR B  72
GLU B  51
GLY B  52
 None
 1.14A 1kqbC-1usvB:
undetectable
1kqbD-1usvB:
undetectable		 1kqbC-1usvB:
19.40
1kqbD-1usvB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 6 GLU B  51
GLY B  52
SER B  49
THR B  72
 None
 1.11A 1kqbC-1usvB:
undetectable
1kqbD-1usvB:
undetectable		 1kqbC-1usvB:
19.40
1kqbD-1usvB:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1usv AHA1
(Saccharomyces
cerevisiae) 		5 / 12 ILE B  50
VAL B  98
ILE B 127
ILE B 138
ILE B  44
 None
 1.00A 1oipA-1usvB:
undetectable		 1oipA-1usvB:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 1usv AHA1
(Saccharomyces
cerevisiae) 		5 / 12 GLY B  34
ALA B  33
ILE B 127
ILE B  75
GLY B  77
 None
 0.76A 1sguB-1usvB:
undetectable		 1sguB-1usvB:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 8 ALA B  33
ILE B 127
ILE B  75
GLY B  77
 None
 0.51A 1sh9A-1usvB:
undetectable		 1sh9A-1usvB:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 1usv AHA1
(Saccharomyces
cerevisiae) 		5 / 12 GLY B  34
ALA B  33
ILE B 127
ILE B  75
GLY B  77
 None
 0.88A 2b60A-1usvB:
undetectable		 2b60A-1usvB:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		5 / 12 GLY B  34
ALA B  33
ILE B 127
ILE B  75
GLY B  77
 None
 0.60A 2hs1A-1usvB:
undetectable		 2hs1A-1usvB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		5 / 12 GLY B  34
ALA B  33
ILE B 127
ILE B  75
GLY B  77
 None
 0.67A 2hs1B-1usvB:
undetectable		 2hs1B-1usvB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 343
THR A 351
MET A 389
LEU A 378
ASN A 386
 None
 1.35A 2ydoA-1usvA:
undetectable		 2ydoA-1usvA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		4 / 6 GLY B  52
ILE B  17
ILE B  50
ASP B  68
 None
 0.93A 3a7eA-1usvB:
undetectable		 3a7eA-1usvB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 474
THR A 525
ASP A 523
THR A 475
VAL A 482
 None
 1.30A 3kpbD-1usvA:
undetectable		 3kpbD-1usvA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 289
ILE A 396
LEU A 321
PHE A 322
 None
 1.21A 3ls4L-1usvA:
undetectable		 3ls4L-1usvA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 499
LYS A 426
LEU A 479
GLY A 476
PHE A 510
 None
 1.42A 4pgfA-1usvA:
undetectable		 4pgfA-1usvA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1usv AHA1
(Saccharomyces
cerevisiae) 		5 / 11 GLY B  34
ALA B  33
ILE B 127
ILE B  75
GLY B  77
 None
 0.60A 4q1xA-1usvB:
undetectable		 4q1xA-1usvB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 8 ILE A 396
LEU A 400
ILE A 358
ASN A 340
SER A 297
 None
 1.41A 5numA-1usvA:
undetectable		 5numA-1usvA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 10 VAL A 429
GLY A 428
ASP A 506
ALA A 509
LEU A 443
 None
 1.20A 5x6yB-1usvA:
2.1		 5x6yB-1usvA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 1usv HEAT SHOCK PROTEIN
HSP82
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 499
LYS A 426
LEU A 479
GLY A 476
PHE A 510
 None
 1.41A 6gbnB-1usvA:
undetectable		 6gbnB-1usvA:
21.27