SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ut1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.52A 1usqA-1ut1A:
27.4		 1usqA-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 1usqB-1ut1A:
27.4		 1usqB-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.52A 1usqC-1ut1A:
27.4		 1usqC-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 1usqD-1ut1A:
27.3		 1usqD-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 1usqE-1ut1A:
27.2		 1usqE-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.49A 1usqF-1ut1A:
27.7		 1usqF-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 2jkjA-1ut1A:
27.2		 2jkjA-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 2jkjB-1ut1A:
26.9		 2jkjB-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 2jkjC-1ut1A:
27.1		 2jkjC-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		5 / 5 PRO A  40
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
 0.53A 2jkjD-1ut1A:
27.2		 2jkjD-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.48A 2jkjE-1ut1A:
26.1		 2jkjE-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		5 / 5 PRO A  40
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
 0.54A 2jkjF-1ut1A:
27.4		 2jkjF-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.49A 2jklA-1ut1A:
27.4		 2jklA-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.49A 2jklB-1ut1A:
27.4		 2jklB-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.51A 2jklC-1ut1A:
27.2		 2jklC-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.50A 2jklD-1ut1A:
27.3		 2jklD-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.48A 2jklE-1ut1A:
27.1		 2jklE-1ut1A:
99.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		7 / 7 PRO A  40
GLY A  42
PRO A  43
THR A  88
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
None
 0.49A 2jklF-1ut1A:
27.7		 2jklF-1ut1A:
99.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		4 / 7 THR A  16
GLN A  34
LEU A  35
LEU A  13
 EDO  A1141 (-4.4A)
EDO  A1143 (-4.7A)
None
None
 0.92A 3bgdB-1ut1A:
undetectable		 3bgdB-1ut1A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		4 / 8 LEU A  35
GLY A  42
THR A  11
LEU A  72
 None
 0.88A 5eseA-1ut1A:
undetectable		 5eseA-1ut1A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 11 ILE A 112
ILE A  85
PHE A  70
VAL A  44
THR A  11
ALA A  60
 None
 1.50A 5lg3A-1ut1A:
undetectable		 5lg3A-1ut1A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT
(Escherichia
coli) 		6 / 12 ILE A 112
ILE A  85
PHE A  70
VAL A  44
THR A  11
ALA A  60
 None
 1.46A 5lg3E-1ut1A:
0.0		 5lg3E-1ut1A:
18.94