SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uty'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 1uty NON-STRUCTURAL
PROTEIN 2
(Bluetongue
virus) 		4 / 8 LEU A  77
VAL A  99
CYH A 122
GLY A 124
 None
 0.95A 1jlfA-1utyA:
undetectable
1jlfB-1utyA:
undetectable		 1jlfA-1utyA:
16.57
1jlfB-1utyA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1uty NON-STRUCTURAL
PROTEIN 2
(Bluetongue
virus) 		5 / 10 ASP A  73
ILE A  75
GLY A  55
ILE A 119
ILE A  68
 None
 1.02A 3s43B-1utyA:
undetectable		 3s43B-1utyA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1uty NON-STRUCTURAL
PROTEIN 2
(Bluetongue
virus) 		3 / 3 VAL A  99
LYS A 120
MET A 104
 None
 0.93A 5nknA-1utyA:
0.0		 5nknA-1utyA:
23.81