SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 8 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.92A 2einA-1uv7A:
undetectable
2einJ-1uv7A:
undetectable		 2einA-1uv7A:
11.07
2einJ-1uv7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 8 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.94A 3abkA-1uv7A:
undetectable
3abkJ-1uv7A:
undetectable		 3abkA-1uv7A:
11.07
3abkJ-1uv7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 7 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.85A 5xdxA-1uv7A:
undetectable
5xdxJ-1uv7A:
undetectable		 5xdxA-1uv7A:
11.07
5xdxJ-1uv7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 8 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.93A 5zcpN-1uv7A:
undetectable
5zcpW-1uv7A:
undetectable		 5zcpN-1uv7A:
11.07
5zcpW-1uv7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 8 LEU A 125
THR A  96
VAL A 115
LEU A 159
 None
 0.78A 6czmD-1uv7A:
3.0
6czmF-1uv7A:
3.0		 6czmD-1uv7A:
15.86
6czmF-1uv7A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 7 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.78A 6nmfA-1uv7A:
undetectable
6nmfJ-1uv7A:
undetectable		 6nmfA-1uv7A:
11.07
6nmfJ-1uv7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 7 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.83A 6nmpA-1uv7A:
undetectable
6nmpJ-1uv7A:
undetectable		 6nmpA-1uv7A:
11.07
6nmpJ-1uv7A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1uv7 GENERAL SECRETION
PATHWAY PROTEIN M
(Vibrio
cholerae) 		4 / 5 ILE A 143
LEU A 159
ARG A 147
LEU A 120
 None
 0.78A 6nmpN-1uv7A:
undetectable
6nmpW-1uv7A:
undetectable		 6nmpN-1uv7A:
11.07
6nmpW-1uv7A:
17.27