SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 1uvf SERINE PROTEINASE
INHIBITOR KAZAL TYPE
5
(Homo
sapiens) 		4 / 8 ASP A  28
ASP A  29
TYR A  33
THR A  50
 None
 1.41A 1ceaA-1uvfA:
undetectable
1ceaB-1uvfA:
undetectable		 1ceaA-1uvfA:
18.82
1ceaB-1uvfA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1uvf SERINE PROTEINASE
INHIBITOR KAZAL TYPE
5
(Homo
sapiens) 		4 / 6 ILE A  52
SER A   2
ASN A  43
THR A  48
 None
 1.17A 1h7xA-1uvfA:
undetectable		 1h7xA-1uvfA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1uvf SERINE PROTEINASE
INHIBITOR KAZAL TYPE
5
(Homo
sapiens) 		4 / 6 ILE A  52
SER A   2
ASN A  43
THR A  48
 None
 1.14A 1h7xB-1uvfA:
undetectable		 1h7xB-1uvfA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1uvf SERINE PROTEINASE
INHIBITOR KAZAL TYPE
5
(Homo
sapiens) 		4 / 6 ILE A  52
SER A   2
ASN A  43
THR A  48
 None
 1.16A 1h7xC-1uvfA:
undetectable		 1h7xC-1uvfA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1uvf SERINE PROTEINASE
INHIBITOR KAZAL TYPE
5
(Homo
sapiens) 		4 / 6 ILE A  52
SER A   2
ASN A  43
THR A  48
 None
 1.16A 1h7xD-1uvfA:
undetectable		 1h7xD-1uvfA:
6.15