SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 8 LEU A  53
THR A  16
VAL A  15
LEU A  89
 None
None
XE  A1118 (-4.5A)
None
 0.93A 1fiqC-1uvyA:
undetectable		 1fiqC-1uvyA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 8 LEU A  85
VAL A  12
LEU A   6
ALA A  92
 None
XE  A1118 ( 3.9A)
None
None
 0.85A 1fiqC-1uvyA:
undetectable		 1fiqC-1uvyA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 8 PHE A  19
TYR A  20
ILE A  23
VAL A  81
 None
None
None
HEM  A1117 (-4.4A)
 0.54A 1fslA-1uvyA:
7.9		 1fslA-1uvyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 8 PHE A  19
TYR A  20
ILE A  23
VAL A  81
 None
None
None
HEM  A1117 (-4.4A)
 0.52A 1fslB-1uvyA:
8.0		 1fslB-1uvyA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 8 GLY A   8
GLY A   7
ALA A  10
ALA A  11
 None
 0.62A 2ha4A-1uvyA:
undetectable		 2ha4A-1uvyA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 7 GLY A   8
GLY A   7
ALA A  10
ALA A  11
 None
 0.66A 2ha4B-1uvyA:
undetectable		 2ha4B-1uvyA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		5 / 12 TYR A  20
VAL A  81
GLY A  83
SER A  87
LEU A  89
 None
HEM  A1117 (-4.4A)
None
None
None
 0.98A 3hs6A-1uvyA:
undetectable		 3hs6A-1uvyA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		5 / 9 PHE A  19
TYR A  20
ALA A  47
LEU A  85
ALA A  88
 None
 0.57A 3ozvB-1uvyA:
8.2		 3ozvB-1uvyA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		4 / 8 LEU A  85
VAL A  12
LEU A   6
ALA A  92
 None
XE  A1118 ( 3.9A)
None
None
 0.83A 3uniB-1uvyA:
undetectable		 3uniB-1uvyA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		5 / 12 THR A  16
PHE A  19
TYR A  20
PHE A  33
VAL A  81
 None
None
None
HEM  A1117 (-4.0A)
HEM  A1117 (-4.4A)
 0.96A 4g1bA-1uvyA:
9.2		 4g1bA-1uvyA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		5 / 12 VAL A  99
ALA A  92
VAL A  94
LEU A  53
ILE A  23
 None
 1.16A 5hv1A-1uvyA:
undetectable		 5hv1A-1uvyA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 1uvy MYOGLOBIN
(Paramecium
caudatum) 		6 / 12 ALA A  51
GLY A  55
LEU A  49
VAL A  12
LEU A  64
TRP A  59
 None
None
XE  A1118 ( 4.5A)
XE  A1118 ( 3.9A)
HEM  A1117 (-4.3A)
None
 1.45A 5w7pA-1uvyA:
undetectable		 5w7pA-1uvyA:
16.06