SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uw1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSS_G_CCSG149_0 (D-GLYCERALDEHYDE-3-P HOSPHATE-DEHYDROGENA SE)	1uw1	ARTIFICIAL NUCLEOTIDE BINDING PROTEIN (ANBP) (synthetic construct)	4 / 7	ASN A 32 CYH A 46 ASN A 44 TYR A 43	ADP A1074 ( 4.9A) ZN A1075 (-2.4A) None ADP A1074 (-3.6A)	0.98A	1dssG-1uw1A: undetectable	1dssG-1uw1A: 12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DSS_R_CCSR149_0 (D-GLYCERALDEHYDE-3-P HOSPHATE-DEHYDROGENA SE)	1uw1	ARTIFICIAL NUCLEOTIDE BINDING PROTEIN (ANBP) (synthetic construct)	4 / 8	ASN A 32 CYH A 46 ASN A 44 TYR A 43	ADP A1074 ( 4.9A) ZN A1075 (-2.4A) None ADP A1074 (-3.6A)	1.00A	1dssR-1uw1A: undetectable	1dssR-1uw1A: 12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMT_C_CCSC166_0 (GLYCERALDEHYDE-3-PHO SPHATE DEHYDROGENASE, GLYCOSOMAL)	1uw1	ARTIFICIAL NUCLEOTIDE BINDING PROTEIN (ANBP) (synthetic construct)	4 / 8	ASN A 32 CYH A 46 ASN A 44 TYR A 43	ADP A1074 ( 4.9A) ZN A1075 (-2.4A) None ADP A1074 (-3.6A)	0.94A	3dmtC-1uw1A: undetectable	3dmtC-1uw1A: 12.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DSS_G_CCSG149_0","D-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE","1uw1","ARTIFICIAL NUCLEOTIDE BINDING PROTEIN (ANBP)","synthetic construct",4,"ASN A  32;CYH A  46;ASN A  44;TYR A  43","ADP A1074 ( 4.9A); ZN A1075 (-2.4A);None;ADP A1074 (-3.6A)","0.98A","1dssG-1uw1A:undetectable","1dssG-1uw1A:12.18"],["1DSS_R_CCSR149_0","D-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE","1uw1","ARTIFICIAL NUCLEOTIDE BINDING PROTEIN (ANBP)","synthetic construct",4,"ASN A  32;CYH A  46;ASN A  44;TYR A  43","ADP A1074 ( 4.9A); ZN A1075 (-2.4A);None;ADP A1074 (-3.6A)","1.00A","1dssR-1uw1A:undetectable","1dssR-1uw1A:12.18"],["3DMT_C_CCSC166_0","GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, GLYCOSOMAL","1uw1","ARTIFICIAL NUCLEOTIDE BINDING PROTEIN (ANBP)","synthetic construct",4,"ASN A  32;CYH A  46;ASN A  44;TYR A  43","ADP A1074 ( 4.9A); ZN A1075 (-2.4A);None;ADP A1074 (-3.6A)","0.94A","3dmtC-1uw1A:undetectable","3dmtC-1uw1A:12.50"]]