SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		3 / 3 TRP A 119
ALA A 122
VAL A 120
 None
 0.89A 1c4dA-1uwwA:
undetectable
1c4dB-1uwwA:
undetectable		 1c4dA-1uwwA:
12.00
1c4dB-1uwwA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 9 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 1.00A 1hpvB-1uwwA:
undetectable		 1hpvB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.87A 1hxbB-1uwwA:
undetectable		 1hxbB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		3 / 3 ASN A  67
ALA A 171
ASN A 108
 None
 0.79A 1n4fA-1uwwA:
undetectable		 1n4fA-1uwwA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 PHE A  91
SER A  20
LEU A  74
PHE A 170
VAL A 183
 None
 1.40A 1q23E-1uwwA:
undetectable		 1q23E-1uwwA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.95A 2f80B-1uwwA:
undetectable		 2f80B-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.96A 2f81B-1uwwA:
undetectable		 2f81B-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.89A 2ienB-1uwwA:
undetectable		 2ienB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 9 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.90A 2o4pB-1uwwA:
undetectable		 2o4pB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 9 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.96A 2q5kA-1uwwA:
undetectable		 2q5kA-1uwwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.87A 2qakB-1uwwA:
undetectable		 2qakB-1uwwA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.91A 2qhcA-1uwwA:
undetectable		 2qhcA-1uwwA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.88A 2qhcB-1uwwA:
undetectable		 2qhcB-1uwwA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.92A 2z54A-1uwwA:
undetectable		 2z54A-1uwwA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.90A 2z54B-1uwwA:
undetectable		 2z54B-1uwwA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 GLY A  84
ARG A  83
ILE A 157
LEU A 163
THR A 161
 None
 1.41A 3bexC-1uwwA:
undetectable
3bexD-1uwwA:
undetectable		 3bexC-1uwwA:
21.88
3bexD-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 LEU A 163
THR A 161
GLY A  84
ARG A  83
ILE A 157
 None
 1.40A 3bexC-1uwwA:
undetectable
3bexD-1uwwA:
undetectable		 3bexC-1uwwA:
21.88
3bexD-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 GLY A  84
ARG A  83
ILE A 157
LEU A 163
THR A 161
 None
 1.40A 3bexE-1uwwA:
undetectable
3bexF-1uwwA:
undetectable		 3bexE-1uwwA:
21.88
3bexF-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 LEU A 163
THR A 161
GLY A  84
ARG A  83
ILE A 157
 None
 1.40A 3bexE-1uwwA:
undetectable
3bexF-1uwwA:
undetectable		 3bexE-1uwwA:
21.88
3bexF-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 GLY A  84
ARG A  83
ILE A 157
LEU A 163
THR A 161
 None
 1.40A 3bf1C-1uwwA:
undetectable
3bf1D-1uwwA:
undetectable		 3bf1C-1uwwA:
21.88
3bf1D-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 GLY A  84
ARG A  83
ILE A 157
LEU A 163
THR A 161
 None
 1.37A 3bf1E-1uwwA:
undetectable
3bf1F-1uwwA:
undetectable		 3bf1E-1uwwA:
21.88
3bf1F-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 LEU A 163
THR A 161
GLY A  84
ARG A  83
ILE A 157
 None
 1.39A 3bf1E-1uwwA:
undetectable
3bf1F-1uwwA:
undetectable		 3bf1E-1uwwA:
21.88
3bf1F-1uwwA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.94A 3cywB-1uwwA:
undetectable		 3cywB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.91A 3d20B-1uwwA:
undetectable		 3d20B-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 9 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 1.02A 3ekvB-1uwwA:
undetectable		 3ekvB-1uwwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 1.00A 3ekxB-1uwwA:
undetectable		 3ekxB-1uwwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.91A 3jvyB-1uwwA:
undetectable		 3jvyB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.88A 3k4vC-1uwwA:
undetectable		 3k4vC-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.95A 3mwsB-1uwwA:
undetectable		 3mwsB-1uwwA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.89A 3ndtD-1uwwA:
undetectable		 3ndtD-1uwwA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.92A 3ndwA-1uwwA:
undetectable		 3ndwA-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.99A 3nu6A-1uwwA:
undetectable		 3nu6A-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.88A 3nu6B-1uwwA:
undetectable		 3nu6B-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.87A 3pwrB-1uwwA:
undetectable		 3pwrB-1uwwA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		4 / 8 ASP A  92
HIS A 144
ASP A 184
GLU A 189
 CA  A1194 (-2.4A)
None
CA  A1192 (-2.2A)
None
 1.06A 3sg9B-1uwwA:
undetectable		 3sg9B-1uwwA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.86A 3tl9B-1uwwA:
undetectable		 3tl9B-1uwwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		4 / 7 PHE A  93
TYR A 145
VAL A 147
ILE A 149
 None
 1.13A 4a97E-1uwwA:
undetectable		 4a97E-1uwwA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.98A 4dqcA-1uwwA:
undetectable		 4dqcA-1uwwA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 11 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.98A 4dqeA-1uwwA:
undetectable		 4dqeA-1uwwA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		3 / 3 PHE A  76
VAL A 151
ILE A 149
 None
 0.57A 4emaA-1uwwA:
undetectable		 4emaA-1uwwA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 1.07A 4q1wB-1uwwA:
undetectable		 4q1wB-1uwwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 LEU A  53
LEU A  74
LEU A  42
THR A  43
GLY A 179
 None
 0.96A 6b0cD-1uwwA:
undetectable		 6b0cD-1uwwA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.95A 6dgxA-1uwwA:
undetectable		 6dgxA-1uwwA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 12 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.88A 6difB-1uwwA:
undetectable		 6difB-1uwwA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		5 / 10 ALA A 122
VAL A  89
ILE A 169
VAL A 147
ILE A 149
 None
 0.93A 6dj2A-1uwwA:
undetectable		 6dj2A-1uwwA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uww ENDOGLUCANASE
(Bacillus
akibai) 		3 / 3 LEU A  53
ASN A 165
LEU A  18
 None
 0.68A 6exiA-1uwwA:
undetectable		 6exiA-1uwwA:
17.37