SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ux4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1ux4 BNI1 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 VAL A1659
SER A1662
THR A1684
LEU A1681
 None
 1.07A 3arrA-1ux4A:
3.1		 3arrA-1ux4A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1ux4 BNI1 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 SER A1527
ALA A1531
VAL A1534
 None
 0.68A 4o2bC-1ux4A:
undetectable		 4o2bC-1ux4A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 1ux4 BNI1 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 THR A1603
THR A1604
ASP A1602
TYR A1612
 None
 1.37A 4oltA-1ux4A:
undetectable		 4oltA-1ux4A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1ux4 BNI1 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 GLN A1744
ILE A1737
ASN A1747
ASN A1611
LEU A1610
 None
 1.14A 4r38B-1ux4A:
undetectable		 4r38B-1ux4A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1ux4 BNI1 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 GLN A1744
ILE A1737
ASN A1747
ASN A1611
LEU A1610
 None
 1.18A 4r3aA-1ux4A:
undetectable		 4r3aA-1ux4A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 1ux4 BNI1 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 LEU A1565
LEU A1712
PHE A1569
LEU A1591
 None
 0.69A 5gtrA-1ux4A:
undetectable		 5gtrA-1ux4A:
24.44