SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ux8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JLB_A_NVPA999_1 (HIV-1 RT A-CHAIN)	1ux8	YJBI PROTEIN (Bacillus subtilis)	4 / 8	LEU A 17 TYR A 56 GLY A 59 LEU A 110	None	0.94A	1jlbA-1ux8A: undetectable	1jlbA-1ux8A: 14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1ux8	YJBI PROTEIN (Bacillus subtilis)	5 / 12	LEU A 53 GLY A 59 LEU A 62 LEU A 17 LEU A 20	HEM A 700 (-4.9A) None None None None	0.93A	2nxeA-1ux8A: undetectable	2nxeA-1ux8A: 19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1ux8	YJBI PROTEIN (Bacillus subtilis)	5 / 12	LEU A 53 GLY A 59 LEU A 62 LEU A 17 LEU A 20	HEM A 700 (-4.9A) None None None None	1.00A	3cjtO-1ux8A: undetectable	3cjtO-1ux8A: 19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_2 (PROSTAGLANDIN G/H SYNTHASE 2)	1ux8	YJBI PROTEIN (Bacillus subtilis)	4 / 7	ARG A 107 SER A 91 LEU A 53 PHE A 24	None None HEM A 700 (-4.9A) None	1.06A	3ln1C-1ux8A: undetectable	3ln1C-1ux8A: 11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_A_CHDA503_0 (FERROCHELATASE, MITOCHONDRIAL)	1ux8	YJBI PROTEIN (Bacillus subtilis)	5 / 10	LEU A 110 LEU A 53 ARG A 113 THR A 45 HIS A 76	None HEM A 700 (-4.9A) None HEM A 700 (-3.1A) HEM A 700 (-3.1A)	1.41A	4mk4A-1ux8A: undetectable	4mk4A-1ux8A: 16.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JLB_A_NVPA999_1","HIV-1 RT A-CHAIN","1ux8","YJBI PROTEIN","Bacillus subtilis",4,"LEU A  17;TYR A  56;GLY A  59;LEU A 110","None","0.94A","1jlbA-1ux8A:undetectable","1jlbA-1ux8A:14.84"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1ux8","YJBI PROTEIN","Bacillus subtilis",5,"LEU A  53;GLY A  59;LEU A  62;LEU A  17;LEU A  20","HEM A 700 (-4.9A);None;None;None;None","0.93A","2nxeA-1ux8A:undetectable","2nxeA-1ux8A:19.61"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1ux8","YJBI PROTEIN","Bacillus subtilis",5,"LEU A  53;GLY A  59;LEU A  62;LEU A  17;LEU A  20","HEM A 700 (-4.9A);None;None;None;None","1.00A","3cjtO-1ux8A:undetectable","3cjtO-1ux8A:19.61"],["3LN1_C_CELC682_2","PROSTAGLANDIN G\/H SYNTHASE 2","1ux8","YJBI PROTEIN","Bacillus subtilis",4,"ARG A 107;SER A  91;LEU A  53;PHE A  24","None;None;HEM A 700 (-4.9A);None","1.06A","3ln1C-1ux8A:undetectable","3ln1C-1ux8A:11.28"],["4MK4_A_CHDA503_0","FERROCHELATASE, MITOCHONDRIAL","1ux8","YJBI PROTEIN","Bacillus subtilis",5,"LEU A 110;LEU A  53;ARG A 113;THR A  45;HIS A  76","None;HEM A 700 (-4.9A);None;HEM A 700 (-3.1A);HEM A 700 (-3.1A)","1.41A","4mk4A-1ux8A:undetectable","4mk4A-1ux8A:16.81"]]