SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uxe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		4 / 7 ILE A 337
LEU A 248
PHE A 250
THR A 185
 None
 1.04A 2zxwN-1uxeA:
undetectable
2zxwW-1uxeA:
undetectable		 2zxwN-1uxeA:
16.05
2zxwW-1uxeA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		4 / 7 ILE A 337
LEU A 248
PHE A 250
THR A 185
 None
 1.06A 3ag4N-1uxeA:
undetectable
3ag4W-1uxeA:
undetectable		 3ag4N-1uxeA:
16.05
3ag4W-1uxeA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		4 / 7 VAL A 225
PHE A 244
LEU A 313
ILE A 233
 None
 1.01A 3rfmA-1uxeA:
undetectable		 3rfmA-1uxeA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		4 / 6 ILE A 224
GLY A 314
VAL A 350
HIS A 231
 None
None
None
ZN  A1366 ( 3.2A)
 1.05A 4oltA-1uxeA:
undetectable		 4oltA-1uxeA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		4 / 6 ILE A 224
GLY A 314
VAL A 350
HIS A 231
 None
None
None
ZN  A1366 ( 3.2A)
 1.01A 4oltB-1uxeA:
undetectable		 4oltB-1uxeA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		5 / 12 TYR A 280
SER A 260
GLY A 263
LEU A 262
ILE A 284
 None
 1.38A 5fepA-1uxeA:
undetectable		 5fepA-1uxeA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		5 / 12 TYR A 280
SER A 260
GLY A 263
LEU A 262
ILE A 284
 None
 1.38A 5fesA-1uxeA:
undetectable		 5fesA-1uxeA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		5 / 12 LEU A 208
LEU A 210
LEU A 262
ALA A 283
MET A 287
 None
 0.95A 5og9B-1uxeA:
0.0		 5og9B-1uxeA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1uxe FIBER PROTEIN
(Human
mastadenovirus
D) 		3 / 3 ASN A 234
VAL A 225
HIS A 231
 None
None
ZN  A1366 ( 3.2A)
 0.87A 6a5yD-1uxeA:
undetectable		 6a5yD-1uxeA:
17.79