SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 VAL A  61
ASN A 121
ALA A   8
ILE A  34
ILE A 113
 None
 0.95A 1fk6A-1uxzA:
undetectable		 1fk6A-1uxzA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 9 GLY A  16
ASP A  35
ILE A  34
VAL A  31
GLN A  18
 None
 1.46A 3fi0O-1uxzA:
undetectable		 3fi0O-1uxzA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		4 / 7 GLY A  16
ASP A  35
ILE A  34
GLN A  18
 None
 0.90A 3fi0P-1uxzA:
undetectable		 3fi0P-1uxzA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 ASN A  65
ASP A  35
GLY A 118
GLY A 119
GLY A  32
 None
 1.00A 3uboA-1uxzA:
undetectable		 3uboA-1uxzA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		4 / 8 SER A 105
LEU A 104
PHE A 111
PRO A  50
 None
 1.13A 4j7uD-1uxzA:
undetectable		 4j7uD-1uxzA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		4 / 4 TYR A  59
THR A  83
VAL A 102
ILE A 113
 None
 1.45A 4jx1F-1uxzA:
undetectable		 4jx1F-1uxzA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 4qvnH-1uxzA:
undetectable
4qvnI-1uxzA:
undetectable		 4qvnH-1uxzA:
20.17
4qvnI-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 10 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 4qvnV-1uxzA:
undetectable
4qvnW-1uxzA:
undetectable		 4qvnV-1uxzA:
20.17
4qvnW-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 4qvpH-1uxzA:
undetectable
4qvpI-1uxzA:
undetectable		 4qvpH-1uxzA:
20.17
4qvpI-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 4qvpV-1uxzA:
undetectable
4qvpW-1uxzA:
undetectable		 4qvpV-1uxzA:
20.17
4qvpW-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 4qvqH-1uxzA:
undetectable
4qvqI-1uxzA:
undetectable		 4qvqH-1uxzA:
20.17
4qvqI-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 4qvqV-1uxzA:
undetectable
4qvqW-1uxzA:
undetectable		 4qvqV-1uxzA:
20.17
4qvqW-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.19A 4qvyV-1uxzA:
undetectable
4qvyW-1uxzA:
undetectable		 4qvyV-1uxzA:
20.17
4qvyW-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 4qw0H-1uxzA:
undetectable
4qw0I-1uxzA:
undetectable		 4qw0H-1uxzA:
20.17
4qw0I-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.20A 4qw0V-1uxzA:
undetectable
4qw0W-1uxzA:
undetectable		 4qw0V-1uxzA:
20.17
4qw0W-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 4qw1H-1uxzA:
undetectable
4qw1I-1uxzA:
undetectable		 4qw1H-1uxzA:
20.17
4qw1I-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 4qw1V-1uxzA:
undetectable
4qw1W-1uxzA:
undetectable		 4qw1V-1uxzA:
20.17
4qw1W-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.23A 4qwuH-1uxzA:
undetectable
4qwuI-1uxzA:
undetectable		 4qwuH-1uxzA:
20.17
4qwuI-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.23A 4qwuV-1uxzA:
undetectable
4qwuW-1uxzA:
undetectable		 4qwuV-1uxzA:
20.17
4qwuW-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 11 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 5bxnH-1uxzA:
undetectable
5bxnI-1uxzA:
undetectable		 5bxnH-1uxzA:
18.57
5bxnI-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 5cz7V-1uxzA:
undetectable
5cz7W-1uxzA:
undetectable		 5cz7V-1uxzA:
20.17
5cz7W-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 9 ALA A  36
ASP A  35
ASP A  38
GLY A  68
THR A  71
 None
 1.16A 5kr2A-1uxzA:
undetectable		 5kr2A-1uxzA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 5l5fH-1uxzA:
undetectable
5l5fI-1uxzA:
undetectable		 5l5fH-1uxzA:
20.17
5l5fI-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 5l5fV-1uxzA:
undetectable
5l5fW-1uxzA:
undetectable		 5l5fV-1uxzA:
20.17
5l5fW-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.22A 5l66H-1uxzA:
undetectable
5l66I-1uxzA:
undetectable		 5l66H-1uxzA:
20.17
5l66I-1uxzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1uxz CELLULASE B
(Cellvibrio
mixtus) 		5 / 12 GLY A  91
THR A  94
ALA A  62
THR A  89
ASP A  24
 None
 1.21A 5l66V-1uxzA:
undetectable
5l66W-1uxzA:
undetectable		 5l66V-1uxzA:
20.17
5l66W-1uxzA:
20.49