SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uy4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		4 / 8 TYR A  60
LEU A  37
VAL A 134
PHE A 139
 None
 1.00A 1gsfC-1uy4A:
undetectable		 1gsfC-1uy4A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		4 / 7 THR A  36
ALA A  26
TYR A  60
PHE A 130
 None
 1.18A 2hzqA-1uy4A:
undetectable		 2hzqA-1uy4A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 12 ALA A  74
PHE A  72
ILE A  63
ALA A  26
VAL A  58
 None
 0.98A 3rukB-1uy4A:
undetectable		 3rukB-1uy4A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 12 ALA A  74
PHE A  72
ILE A  63
ALA A  26
VAL A  58
 None
 0.94A 4nkvA-1uy4A:
undetectable		 4nkvA-1uy4A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 12 ALA A  74
PHE A  72
ILE A  63
ALA A  26
VAL A  58
 None
 0.94A 4nkvB-1uy4A:
undetectable		 4nkvB-1uy4A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 12 ALA A  74
PHE A  72
ILE A  63
ALA A  26
VAL A  58
 None
 0.97A 4nkvC-1uy4A:
undetectable		 4nkvC-1uy4A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 12 ALA A  74
PHE A  72
ILE A  63
ALA A  26
VAL A  58
 None
 0.96A 4nkvD-1uy4A:
undetectable		 4nkvD-1uy4A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 9 PHE A 141
ILE A  84
VAL A 129
GLY A  97
THR A  94
 None
None
None
None
GOL  A1152 (-3.7A)
 1.17A 4r20B-1uy4A:
undetectable		 4r20B-1uy4A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 1uy4 ENDO-1,4-BETA-XYLANA
SE A
([Clostridium]
stercorarium) 		5 / 12 SER A 142
THR A 112
ASN A 111
VAL A  76
LEU A  99
 None
 1.18A 5kocB-1uy4A:
undetectable		 5kocB-1uy4A:
16.24