SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.05A 1p7lC-1uyoX:
undetectable		 1p7lC-1uyoX:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.06A 1p7lD-1uyoX:
undetectable		 1p7lD-1uyoX:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.06A 1rg9A-1uyoX:
undetectable		 1rg9A-1uyoX:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.06A 1rg9B-1uyoX:
undetectable		 1rg9B-1uyoX:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.05A 1rg9C-1uyoX:
undetectable		 1rg9C-1uyoX:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.06A 1rg9D-1uyoX:
undetectable		 1rg9D-1uyoX:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 5 TYR X 905
ARG X 907
MET X 931
LEU X 959
 None
 1.31A 3ag4J-1uyoX:
undetectable		 3ag4J-1uyoX:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 7 LEU X 930
LEU X 960
THR X 983
VAL X 985
 None
 0.79A 3d2tA-1uyoX:
undetectable		 3d2tA-1uyoX:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1uyo NALP
(Neisseria
meningitidis) 		3 / 3 ASN X 940
ASP X 892
ARG X1077
 None
 0.75A 3k13C-1uyoX:
undetectable		 3k13C-1uyoX:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 5 SER X 809
ASP X 892
ASP X 895
ILE X 896
 None
 1.18A 3uj7B-1uyoX:
undetectable		 3uj7B-1uyoX:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 6 LEU X 987
ASP X 958
VAL X 808
ALA X 807
 None
 1.02A 4nkvC-1uyoX:
undetectable		 4nkvC-1uyoX:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 6 LEU X 987
ASP X 958
VAL X 808
ALA X 807
 None
 1.01A 4nkxA-1uyoX:
undetectable		 4nkxA-1uyoX:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1uyo NALP
(Neisseria
meningitidis) 		3 / 3 ASP X 958
LEU X 805
GLY X 802
 None
 0.54A 4xmfA-1uyoX:
undetectable		 4xmfA-1uyoX:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1uyo NALP
(Neisseria
meningitidis) 		5 / 11 THR X 845
SER X 882
ALA X 878
ASP X 799
GLY X 802
 None
 1.25A 4zjoD-1uyoX:
undetectable		 4zjoD-1uyoX:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 8 ASP X1050
SER X 993
THR X1005
PHE X1003
 None
 1.15A 5t8sB-1uyoX:
undetectable		 5t8sB-1uyoX:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 5 GLN X 827
ASP X 828
SER X1075
ARG X 803
 None
 1.29A 5w4zA-1uyoX:
undetectable		 5w4zA-1uyoX:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1uyo NALP
(Neisseria
meningitidis) 		4 / 5 TYR X 905
ARG X 907
MET X 931
LEU X 959
 None
 1.35A 5z86J-1uyoX:
undetectable		 5z86J-1uyoX:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 1uyo NALP
(Neisseria
meningitidis) 		3 / 3 ALA X 807
PHE X 886
GLN X 801
 None
 0.73A 6eceA-1uyoX:
undetectable		 6eceA-1uyoX:
24.35