SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 1uz8 IGG FAB (IGG3,
KAPPA) HEAVY CHAIN
291-2G3-A
(Mus
musculus) 		3 / 3 ASP B 101
GLU B   6
ARG B  71
 None
 0.86A 1wopA-1uz8B:
0.6		 1wopA-1uz8B:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1uz8 IGG FAB (IGG3,
KAPPA) HEAVY CHAIN
291-2G3-A
(Mus
musculus) 		3 / 3 THR B  87
GLU B 148
HIS B 199
 None
 0.73A 3g1uB-1uz8B:
undetectable		 3g1uB-1uz8B:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1uz8 IGG FAB (IGG3,
KAPPA) HEAVY CHAIN
291-2G3-A
(Mus
musculus) 		4 / 8 ILE B  48
LEU B 109
MET B  82
PHE B  67
 None
 0.91A 4r38B-1uz8B:
undetectable		 4r38B-1uz8B:
21.15