SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 THR A 313
HIS A 315
THR A 317
THR A  32
 None
 0.92A 1c9sT-1uzgA:
undetectable
1c9sU-1uzgA:
undetectable		 1c9sT-1uzgA:
11.48
1c9sU-1uzgA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 158
TYR A 176
GLY A 157
 None
 1.38A 1fkpA-1uzgA:
undetectable		 1fkpA-1uzgA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 THR A 313
HIS A 315
THR A 317
THR A  32
 None
 0.90A 1gtfL-1uzgA:
undetectable
1gtfM-1uzgA:
undetectable		 1gtfL-1uzgA:
11.48
1gtfM-1uzgA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 THR A 313
HIS A 315
THR A 317
THR A  32
 None
 0.89A 1gtfN-1uzgA:
undetectable
1gtfO-1uzgA:
undetectable		 1gtfN-1uzgA:
11.48
1gtfO-1uzgA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 158
TYR A 176
GLY A 157
 None
 1.43A 1lwcA-1uzgA:
undetectable		 1lwcA-1uzgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.82A 1v55P-1uzgA:
undetectable
1v55W-1uzgA:
undetectable		 1v55P-1uzgA:
20.75
1v55W-1uzgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.87A 2dysC-1uzgA:
undetectable
2dysJ-1uzgA:
undetectable		 2dysC-1uzgA:
20.75
2dysJ-1uzgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.77A 2eijP-1uzgA:
undetectable
2eijW-1uzgA:
undetectable		 2eijP-1uzgA:
20.75
2eijW-1uzgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.81A 2eilP-1uzgA:
undetectable
2eilW-1uzgA:
undetectable		 2eilP-1uzgA:
20.75
2eilW-1uzgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 6 HIS A 132
PHE A 191
ARG A 186
GLY A 188
 None
 1.39A 2i30A-1uzgA:
undetectable		 2i30A-1uzgA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		3 / 3 HIS A 315
ILE A 350
LEU A 319
 None
 0.71A 2kceA-1uzgA:
undetectable		 2kceA-1uzgA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 10 ILE A 318
LEU A  41
THR A  32
ILE A 387
GLY A 146
 None
 1.32A 2v0mA-1uzgA:
undetectable		 2v0mA-1uzgA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.75A 2zxwC-1uzgA:
undetectable
2zxwJ-1uzgA:
undetectable		 2zxwC-1uzgA:
20.75
2zxwJ-1uzgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.76A 3asoC-1uzgA:
undetectable
3asoJ-1uzgA:
undetectable		 3asoC-1uzgA:
20.75
3asoJ-1uzgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.41A 3ce6D-1uzgA:
undetectable		 3ce6D-1uzgA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 178
ILE A 141
ALA A 160
THR A 138
ILE A 162
 None
 0.96A 3ddyA-1uzgA:
2.4		 3ddyA-1uzgA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.42A 3n58C-1uzgA:
undetectable		 3n58C-1uzgA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.43A 3n58D-1uzgA:
undetectable		 3n58D-1uzgA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		6 / 10 LEU A 285
ALA A 171
ILE A 172
GLY A 157
ILE A 140
LEU A 179
 None
 1.26A 3ogqA-1uzgA:
undetectable		 3ogqA-1uzgA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.44A 3ondA-1uzgA:
undetectable		 3ondA-1uzgA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.45A 3ondB-1uzgA:
undetectable		 3ondB-1uzgA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 5 PHE A 212
ILE A 195
GLY A 127
THR A  55
 None
 1.01A 4ejjC-1uzgA:
undetectable		 4ejjC-1uzgA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 4 LEU A 214
PRO A 215
LEU A 216
ILE A 125
 None
 0.99A 4f4dB-1uzgA:
undetectable		 4f4dB-1uzgA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 5 LEU A 214
PRO A 215
LEU A 216
ILE A 125
 None
 0.79A 4klrA-1uzgA:
undetectable		 4klrA-1uzgA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 LEU A  25
MET A 287
LEU A  41
HIS A 144
 None
 0.97A 4ok1A-1uzgA:
undetectable		 4ok1A-1uzgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 7 LYS A  47
LEU A  45
GLN A  46
LEU A 281
 None
 0.96A 5b3sP-1uzgA:
undetectable		 5b3sP-1uzgA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 THR A  32
THR A 313
HIS A 315
THR A 317
 None
 0.94A 5eevL-1uzgA:
undetectable
5eevV-1uzgA:
undetectable		 5eevL-1uzgA:
11.48
5eevV-1uzgA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 THR A  32
THR A 313
HIS A 315
THR A 317
 None
 0.94A 5eewL-1uzgA:
undetectable
5eewV-1uzgA:
undetectable		 5eewL-1uzgA:
11.48
5eewV-1uzgA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		4 / 8 THR A  32
THR A 313
HIS A 315
THR A 317
 None
 0.94A 5ef3L-1uzgA:
undetectable
5ef3V-1uzgA:
undetectable		 5ef3L-1uzgA:
11.48
5ef3V-1uzgA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 158
GLY A 157
LEU A 179
 None
 1.43A 5hbmA-1uzgA:
undetectable		 5hbmA-1uzgA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 11 PRO A  39
LEU A  41
VAL A 158
TYR A 176
GLY A 157
 None
 1.45A 5hbmA-1uzgA:
undetectable		 5hbmA-1uzgA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.46A 5m66A-1uzgA:
undetectable		 5m66A-1uzgA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.44A 5m66C-1uzgA:
undetectable		 5m66C-1uzgA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 11 VAL A 130
LEU A 189
TYR A 137
THR A  48
ALA A  50
 None
 1.13A 6dk1C-1uzgA:
0.0		 6dk1C-1uzgA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 GLU A  26
LEU A 179
LEU A 173
LEU A 285
LEU A 281
 None
 1.13A 6ew0B-1uzgA:
undetectable		 6ew0B-1uzgA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 GLU A  26
LEU A 179
LEU A 173
LEU A 285
LEU A 281
 None
 1.13A 6ew0D-1uzgA:
undetectable		 6ew0D-1uzgA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 GLU A  26
LEU A 179
LEU A 173
LEU A 285
LEU A 281
 None
 1.13A 6ew0H-1uzgA:
undetectable		 6ew0H-1uzgA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 GLU A  26
LEU A 179
LEU A 173
LEU A 285
LEU A 281
 None
 1.12A 6ew0I-1uzgA:
undetectable		 6ew0I-1uzgA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A 313
THR A  40
ASP A  42
LEU A 319
PHE A  11
 None
 1.42A 6f3nB-1uzgA:
undetectable		 6f3nB-1uzgA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1uzg MAJOR ENVELOPE
PROTEIN E
(Dengue
virus) 		5 / 12 THR A  48
ALA A 171
LEU A  45
ARG A   2
LEU A 181
 None
 1.32A 6ie8A-1uzgA:
undetectable		 6ie8A-1uzgA:
18.64