SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1uzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1uzj FIBRILLIN-1
(Homo
sapiens) 		3 / 3 ALA A1560
GLY A1591
SER A1499
 None
 0.53A 2ivuA-1uzjA:
undetectable		 2ivuA-1uzjA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1uzj FIBRILLIN-1
(Homo
sapiens) 		4 / 5 ASP A1537
ASN A1551
ILE A1553
VAL A1645
 None
 1.18A 4hytA-1uzjA:
undetectable		 4hytA-1uzjA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1uzj FIBRILLIN-1
(Homo
sapiens) 		4 / 4 GLY A1554
LEU A1613
VAL A1557
GLU A1612
 None
 0.98A 5yw0A-1uzjA:
0.0		 5yw0A-1uzjA:
18.04