SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 7 TYR A 429
HIS A 433
LEU A 384
TYR A 331
 None
 1.20A 1tuvA-1v02A:
undetectable		 1tuvA-1v02A:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 7 TYR A 401
GLY A 255
TYR A 138
ASP A 241
 None
 0.90A 2g72B-1v02A:
undetectable		 2g72B-1v02A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 6 ARG A 426
GLY A 408
PHE A 469
THR A 466
 None
 1.35A 2m2oB-1v02A:
undetectable		 2m2oB-1v02A:
5.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 ILE A  65
ALA A  74
GLY A 464
SER A  77
ASN A  70
 None
 1.12A 2okcA-1v02A:
undetectable		 2okcA-1v02A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 11 ASN A 188
GLU A 189
TYR A 331
GLU A 404
TRP A 453
 None
 0.79A 2v3dB-1v02A:
2.7		 2v3dB-1v02A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 10 PHE A  25
GLY A 449
ALA A  95
PHE A  31
LEU A 491
 None
 1.12A 3a3yA-1v02A:
undetectable		 3a3yA-1v02A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 PRO A 418
LEU A 421
ARG A 489
 None
 0.89A 3aqiA-1v02A:
undetectable		 3aqiA-1v02A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 CYH A 194
MET A 300
ALA A 304
VAL A 308
LEU A 232
 None
 1.29A 3b0wB-1v02A:
undetectable		 3b0wB-1v02A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 VAL A 212
GLY A 219
SER A 221
LEU A 222
LEU A 349
 None
 1.00A 3hs6A-1v02A:
0.0		 3hs6A-1v02A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 4 PRO A 205
THR A  53
GLY A 109
THR A 110
 None
 1.17A 3ib1A-1v02A:
undetectable		 3ib1A-1v02A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 PHE A 335
GLY A 362
ASP A 386
GLY A 383
ASN A 378
 None
 1.31A 3jzjA-1v02A:
undetectable		 3jzjA-1v02A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ASP A  67
SER A  69
ARG A 476
 None
 0.66A 3loqA-1v02A:
undetectable		 3loqA-1v02A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 6 ILE A 326
HIS A 236
PRO A 190
LEU A 258
 None
 1.03A 3oi8A-1v02A:
undetectable		 3oi8A-1v02A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 TYR A  78
ASP A  76
ASP A  72
 None
 0.94A 3ou7B-1v02A:
undetectable		 3ou7B-1v02A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 8 LEU A  30
ASP A  94
ALA A  95
TYR A 138
 None
 1.08A 3rodA-1v02A:
undetectable		 3rodA-1v02A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 7 GLY A  42
ASP A  72
GLY A  71
HIS A  59
 None
 0.88A 4c5nA-1v02A:
2.3		 4c5nA-1v02A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 8 GLY A  42
ASP A  72
GLY A  71
HIS A  59
 None
 0.81A 4c5nC-1v02A:
2.3		 4c5nC-1v02A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 TYR A 226
ARG A 307
SER A 223
 None
 1.14A 4dr2I-1v02A:
undetectable
4dr2J-1v02A:
undetectable		 4dr2I-1v02A:
12.66
4dr2J-1v02A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 7 GLY A 406
ILE A 377
ASN A 374
MET A  91
 None
 1.12A 4g0vA-1v02A:
undetectable		 4g0vA-1v02A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ARG A 234
GLU A 160
ASN A 231
 None
 0.48A 4imaD-1v02A:
9.6		 4imaD-1v02A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ARG A 234
GLU A 160
ASN A 231
 None
 0.41A 4ip7D-1v02A:
3.1		 4ip7D-1v02A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 8 TYR A 166
LEU A 150
GLY A 156
PHE A 157
 None
 0.89A 4iqqD-1v02A:
undetectable		 4iqqD-1v02A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 LEU A 437
ASP A 446
GLY A 444
SER A 440
LEU A 388
 None
 1.01A 4lmnA-1v02A:
undetectable		 4lmnA-1v02A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ASP A 145
TRP A 453
SER A  99
 None
 1.02A 4lrhB-1v02A:
undetectable		 4lrhB-1v02A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ASP A 145
TRP A 453
SER A  99
 None
 1.10A 4lrhF-1v02A:
undetectable		 4lrhF-1v02A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 6 ASP A  72
ASP A  55
SER A 101
ALA A  74
 None
 1.05A 4nedA-1v02A:
undetectable		 4nedA-1v02A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 5 ILE A 410
ARG A 426
ASP A 457
GLU A 467
 None
 1.19A 4nkxC-1v02A:
0.0		 4nkxC-1v02A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 PHE A 459
ILE A  65
HIS A  59
ASP A  55
SER A  52
 None
 1.43A 4r88A-1v02A:
7.2		 4r88A-1v02A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ASN A 188
PHE A 451
TYR A  96
 None
 0.71A 4u15A-1v02A:
undetectable		 4u15A-1v02A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 TYR A  81
TYR A  38
ASP A  76
ALA A  74
TYR A 465
 None
 1.27A 4ymgB-1v02A:
undetectable		 4ymgB-1v02A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 4 VAL A 447
ILE A 387
ASN A 405
VAL A 436
 None
 1.23A 5ajqA-1v02A:
undetectable		 5ajqA-1v02A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 ASP A 281
ASP A 386
LYS A 382
GLY A 262
SER A 279
 None
 1.24A 5hfjH-1v02A:
undetectable		 5hfjH-1v02A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 TYR A 166
TYR A 123
SER A  99
 None
 0.99A 5iktB-1v02A:
0.0		 5iktB-1v02A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 6 TYR A 166
LEU A 150
GLY A 156
PHE A 157
 None
 1.00A 5nooC-1v02A:
undetectable		 5nooC-1v02A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 ASN A 374
GLY A 408
VAL A 202
LEU A 203
GLY A 464
 None
 1.18A 5vooF-1v02A:
3.1		 5vooF-1v02A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		5 / 12 ASN A 374
GLY A 408
VAL A 202
LEU A 203
GLY A 464
 None
 1.17A 5vopB-1v02A:
3.1		 5vopB-1v02A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 8 LEU A  88
ILE A  40
PHE A 469
ALA A 452
 None
 0.85A 5y7pC-1v02A:
0.0		 5y7pC-1v02A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 ARG A 426
ILE A 430
SER A 487
 None
 0.86A 5zw2A-1v02A:
undetectable		 5zw2A-1v02A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1v02 DHURRINASE
(Sorghum
bicolor) 		3 / 3 GLY A 464
THR A 466
GLU A 467
 None
 0.59A 6b58A-1v02A:
undetectable		 6b58A-1v02A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 5 LEU A 288
ILE A 242
MET A 325
GLY A 327
 None
 0.84A 6hd6A-1v02A:
undetectable		 6hd6A-1v02A:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1v02 DHURRINASE
(Sorghum
bicolor) 		4 / 8 ASP A 423
ARG A 426
ASN A 495
TYR A 450
 None
 1.24A 6hisD-1v02A:
undetectable
6hisE-1v02A:
undetectable		 6hisD-1v02A:
8.66
6hisE-1v02A:
8.66