SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRE_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ALA A 278
MET A 264
ILE A 190
LEU A 131
TYR A 283
 None
 1.19A 1dreA-1v0bA:
undetectable		 1dreA-1v0bA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 7 LYS A  32
VAL A  63
ARG A 124
LEU A 132
 None
 0.90A 1iepB-1v0bA:
21.8		 1iepB-1v0bA:
27.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ALA A 102
LEU A 261
ILE A 190
LEU A 200
LEU A 253
 None
 0.91A 1xdkF-1v0bA:
undetectable		 1xdkF-1v0bA:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 12 ILE A  10
VAL A  18
LYS A  32
VAL A  63
PHE A  79
ASN A 130
LEU A 132
 None
 1.14A 2eufB-1v0bA:
29.0		 2eufB-1v0bA:
45.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		8 / 12 VAL A  18
LYS A  32
VAL A  63
PHE A  79
ASP A  85
ASN A 130
LEU A 132
ALA A 142
 None
 0.97A 2eufB-1v0bA:
29.0		 2eufB-1v0bA:
45.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 LEU A 200
ILE A 258
VAL A 195
ALA A 192
LEU A 217
 None
 1.19A 2japA-1v0bA:
undetectable		 2japA-1v0bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 LEU A 200
ILE A 258
VAL A 195
ALA A 192
LEU A 217
 None
 1.18A 2japB-1v0bA:
undetectable		 2japB-1v0bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 LEU A 200
ILE A 258
VAL A 195
ALA A 192
LEU A 217
 None
 1.19A 2japC-1v0bA:
undetectable		 2japC-1v0bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 LEU A 200
ILE A 258
VAL A 195
ALA A 192
LEU A 217
 None
 1.17A 2japD-1v0bA:
undetectable		 2japD-1v0bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 4 PRO A 128
ASP A  85
ASP A  83
ASP A  91
 None
 1.22A 2nyuA-1v0bA:
undetectable		 2nyuA-1v0bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 11 LEU A  54
ILE A  51
PHE A  79
PHE A 150
LEU A  75
 None
 1.15A 2q6hA-1v0bA:
undetectable		 2q6hA-1v0bA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 LEU A  54
ILE A  51
PHE A  79
PHE A 150
LEU A  75
 None
 1.14A 2qb4A-1v0bA:
0.0		 2qb4A-1v0bA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 11 LEU A  54
ILE A  51
PHE A  79
PHE A 150
LEU A  75
 None
 1.18A 2qeiA-1v0bA:
undetectable		 2qeiA-1v0bA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 11 LEU A  54
ILE A  51
PHE A  79
PHE A 150
LEU A  75
 None
 1.13A 2qjuA-1v0bA:
0.0		 2qjuA-1v0bA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ILE A  51
ILE A  62
LEU A  57
CYH A 116
HIS A 123
 None
 1.18A 2qo5A-1v0bA:
undetectable		 2qo5A-1v0bA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ALA A 278
MET A 264
ILE A 190
LEU A 131
TYR A 283
 None
 1.23A 2zzaA-1v0bA:
undetectable		 2zzaA-1v0bA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ALA A 278
MET A 264
ILE A 190
LEU A 131
TYR A 283
 None
 1.25A 2zzaB-1v0bA:
undetectable		 2zzaB-1v0bA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 LEU A 131
LEU A  97
PHE A 191
LEU A 260
LEU A 279
 None
 1.38A 3adsA-1v0bA:
undetectable		 3adsA-1v0bA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BBT_D_FMMD91_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 12 VAL A  18
ALA A  30
LYS A  32
LEU A  77
LEU A 132
ASP A 143
LEU A 146
 None
 0.69A 3bbtD-1v0bA:
24.4		 3bbtD-1v0bA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 5 TYR A  66
ALA A  21
TYR A  19
MET A   1
 None
 1.25A 3d91A-1v0bA:
undetectable		 3d91A-1v0bA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ALA A 278
MET A 264
ILE A 190
LEU A 131
TYR A 283
 None
 1.16A 3ia4A-1v0bA:
undetectable		 3ia4A-1v0bA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ALA A 278
MET A 264
ILE A 190
LEU A 131
TYR A 283
 None
 1.19A 3ia4B-1v0bA:
undetectable		 3ia4B-1v0bA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ALA A 278
MET A 264
ILE A 190
LEU A 131
TYR A 283
 None
 1.20A 3ia4C-1v0bA:
undetectable		 3ia4C-1v0bA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 11 ILE A  10
ALA A  30
VAL A  63
PHE A  79
LEU A 132
ASP A 143
 None
 0.61A 3miyA-1v0bA:
23.3		 3miyA-1v0bA:
25.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 7 LYS A  32
LEU A  57
VAL A 121
LEU A 132
 None
 0.67A 3rgfA-1v0bA:
24.9		 3rgfA-1v0bA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 9 ILE A  10
ALA A  30
VAL A  63
PHE A  79
ASP A  85
LYS A  87
LEU A 132
 None
 0.75A 3ti1A-1v0bA:
37.6		 3ti1A-1v0bA:
62.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 9 VAL A  63
PHE A  79
ASP A  85
LYS A  87
LEU A 132
ASP A 143
 None
 1.08A 3ti1A-1v0bA:
37.6		 3ti1A-1v0bA:
62.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_1
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 12 GLY A  16
VAL A  18
ALA A  30
VAL A  63
LEU A 132
ASP A 143
 None
 0.80A 3v5wA-1v0bA:
9.2		 3v5wA-1v0bA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 5 LYS A  32
VAL A  63
LEU A 132
ASP A 143
 None
 0.97A 3wzdA-1v0bA:
21.8		 3wzdA-1v0bA:
25.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KS8_A_B49A701_1
(SERINE/THREONINE-PRO
TEIN KINASE PAK 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 10 ILE A  10
ALA A  30
VAL A  63
LEU A  82
LEU A 132
ASP A 143
 None
 0.72A 4ks8A-1v0bA:
11.8		 4ks8A-1v0bA:
28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 7 VAL A  18
ALA A  30
ASP A  85
LEU A 132
 None
 0.69A 4l9iA-1v0bA:
8.7		 4l9iA-1v0bA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 8 VAL A  18
ALA A  30
LYS A  32
ASP A  85
LEU A 132
 None
 0.98A 4l9iB-1v0bA:
21.2		 4l9iB-1v0bA:
19.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 8 ILE A  10
GLY A  13
VAL A  18
ALA A  30
ASN A 130
LEU A 132
 None
 0.72A 4ogrA-1v0bA:
30.2		 4ogrA-1v0bA:
39.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 8 VAL A  18
ALA A  30
ASP A  85
ASN A 130
LEU A 132
 None
 0.43A 4ogrA-1v0bA:
30.2		 4ogrA-1v0bA:
39.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 7 ALA A  30
ASP A  85
ASN A 130
LEU A 132
ASP A 143
 None
 0.72A 4ogrE-1v0bA:
29.4		 4ogrE-1v0bA:
39.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 7 GLY A  11
ALA A  30
ASP A  85
ASN A 130
LEU A 132
 None
 0.95A 4ogrE-1v0bA:
29.4		 4ogrE-1v0bA:
39.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 9 ILE A  10
GLY A  13
VAL A  18
ALA A  30
ASP A  85
ASN A 130
LEU A 132
 None
 0.84A 4ogrI-1v0bA:
30.1		 4ogrI-1v0bA:
39.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 9 VAL A  18
ALA A  30
ASP A  85
ASN A 130
LEU A 132
ASP A 143
 None
 0.75A 4ogrI-1v0bA:
30.1		 4ogrI-1v0bA:
39.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTI_A_MI1A1001_1
(SERINE/THREONINE-PRO
TEIN KINASE N1)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 12 GLY A  16
VAL A  18
ALA A  30
VAL A  63
LEU A 132
ALA A 142
ASP A 143
 None
 0.63A 4otiA-1v0bA:
21.0		 4otiA-1v0bA:
28.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 LEU A  77
LEU A  82
ASN A 130
 None
 0.55A 4otwA-1v0bA:
24.4		 4otwA-1v0bA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 12 ILE A  10
GLY A  11
VAL A  18
ALA A  30
LEU A  82
LEU A 132
 None
 0.45A 4qmzA-1v0bA:
23.8		 4qmzA-1v0bA:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 8 VAL A  18
LYS A  32
HIS A 123
LEU A 132
 None
 0.74A 4qrcA-1v0bA:
22.0		 4qrcA-1v0bA:
25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 10 VAL A  18
LEU A  57
ILE A  62
VAL A  63
ARG A 124
ILE A 141
 None
 0.86A 4u0iA-1v0bA:
21.4		 4u0iA-1v0bA:
26.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 6 ALA A 168
LEU A 172
MET A 173
LEU A 231
 None
 1.22A 4xp3A-1v0bA:
29.1		 4xp3A-1v0bA:
36.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 GLY A 257
LEU A 109
PHE A 144
ILE A  62
LEU A 279
 None
 1.11A 4ze2A-1v0bA:
undetectable		 4ze2A-1v0bA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		4 / 5 TYR A  19
LYS A   9
GLU A  12
GLY A  16
 None
 0.82A 5jhdJ-1v0bA:
0.0		 5jhdJ-1v0bA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 THR A 180
SER A 179
TYR A 178
 None
 0.76A 5jsdA-1v0bA:
undetectable		 5jsdA-1v0bA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 THR A 180
SER A 179
TYR A 178
 None
 0.77A 5jsdB-1v0bA:
undetectable		 5jsdB-1v0bA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 THR A 180
SER A 179
TYR A 178
 None
 0.75A 5jsdC-1v0bA:
undetectable		 5jsdC-1v0bA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 THR A 180
SER A 179
TYR A 178
 None
 0.78A 5jseA-1v0bA:
undetectable		 5jseA-1v0bA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 THR A 180
SER A 179
TYR A 178
 None
 0.76A 5jseB-1v0bA:
undetectable		 5jseB-1v0bA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		3 / 3 THR A 180
SER A 179
TYR A 178
 None
 0.76A 5jseC-1v0bA:
undetectable		 5jseC-1v0bA:
17.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		8 / 12 GLY A  11
VAL A  18
ALA A  30
VAL A  63
PHE A  79
ASP A  85
LEU A 132
ALA A 142
 None
 0.56A 5l2iA-1v0bA:
17.2		 5l2iA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 12 ILE A  10
GLY A  11
VAL A  18
ALA A  30
VAL A  63
PHE A  79
ASP A  85
 None
 0.99A 5l2iA-1v0bA:
17.2		 5l2iA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 12 ALA A  30
VAL A  63
PHE A  79
HIS A  81
ASP A  85
LEU A 132
ASP A 143
 None
 1.08A 5l2tA-1v0bA:
17.5		 5l2tA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		8 / 12 GLY A  11
ALA A  30
VAL A  63
PHE A  79
HIS A  81
ASP A  85
LEU A 132
ALA A 142
 None
 0.67A 5l2tA-1v0bA:
17.5		 5l2tA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		8 / 12 GLY A  11
VAL A  18
ALA A  30
VAL A  63
PHE A  79
HIS A  81
LEU A 132
ALA A 142
 None
 0.74A 5l2tA-1v0bA:
17.5		 5l2tA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		8 / 12 ILE A  10
GLY A  11
ALA A  30
VAL A  63
PHE A  79
HIS A  81
ASP A  85
LEU A 132
 None
 1.06A 5l2tA-1v0bA:
17.5		 5l2tA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		8 / 12 ILE A  10
GLY A  11
VAL A  18
ALA A  30
VAL A  63
PHE A  79
HIS A  81
LEU A 132
 None
 1.05A 5l2tA-1v0bA:
17.5		 5l2tA-1v0bA:
45.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		7 / 12 VAL A  18
ALA A  30
VAL A  63
PHE A  79
HIS A  81
LEU A 132
ASP A 143
 None
 1.21A 5l2tA-1v0bA:
17.5		 5l2tA-1v0bA:
45.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UH6_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 GLN A 108
LEU A 109
ASP A 118
ILE A  62
ARG A 119
 None
 1.49A 5uh6C-1v0bA:
0.1		 5uh6C-1v0bA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 9 GLY A 197
ALA A 198
GLY A  96
LEU A  97
GLU A  94
 None
 1.30A 5vw4A-1v0bA:
undetectable		 5vw4A-1v0bA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 GLY A  11
VAL A  18
ALA A  30
PHE A  79
ALA A 142
 None
 0.59A 5xv7A-1v0bA:
25.6		 5xv7A-1v0bA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_A_1E8A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 12 GLY A  11
VAL A  18
ALA A  30
LEU A  77
LEU A 132
ASP A 143
 None
 0.51A 5yu9A-1v0bA:
23.6		 5yu9A-1v0bA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_B_1E8B1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		6 / 12 GLY A  11
VAL A  18
ALA A  30
LEU A  77
LEU A 132
ASP A 143
 None
 0.48A 5yu9B-1v0bA:
23.7		 5yu9B-1v0bA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 1v0b CELL DIVISION
CONTROL PROTEIN 2
HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ILE A 113
SER A 186
LEU A  57
ILE A 190
LEU A 131
 None
 1.11A 6dwnC-1v0bA:
undetectable		 6dwnC-1v0bA:
13.31