SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 5 ARG A 151
SER A 257
ASN A 260
SER A 165
 None
None
MG  A 501 ( 4.9A)
None
 1.49A 1kiaB-1v0dA:
undetectable		 1kiaB-1v0dA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 6 ARG A 151
SER A 257
ASN A 260
SER A 165
 None
None
MG  A 501 ( 4.9A)
None
 1.47A 1kiaC-1v0dA:
undetectable		 1kiaC-1v0dA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		5 / 11 ARG A 168
LEU A 171
ARG A 172
SER A 175
LEU A 193
 None
 1.08A 4or0A-1v0dA:
undetectable		 4or0A-1v0dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		5 / 11 ARG A 168
LEU A 171
ARG A 172
SER A 175
LEU A 193
 None
 1.12A 4or0B-1v0dA:
0.9		 4or0B-1v0dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 7 ASN A 245
PRO A 246
PHE A 256
TRP A 259
 None
 1.45A 4v2yB-1v0dA:
undetectable		 4v2yB-1v0dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 8 ASN A 245
PRO A 246
PHE A 256
TRP A 259
 None
 1.48A 4v2zB-1v0dA:
0.0		 4v2zB-1v0dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 7 ASN A 245
PRO A 246
PHE A 256
TRP A 259
 None
 1.42A 5amhA-1v0dA:
undetectable		 5amhA-1v0dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 7 ASN A 245
PRO A 246
PHE A 256
TRP A 259
 None
 1.47A 5amjB-1v0dA:
undetectable		 5amjB-1v0dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 8 ASN A 245
PRO A 246
PHE A 256
TRP A 259
 None
 1.43A 5amkA-1v0dA:
undetectable		 5amkA-1v0dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		5 / 12 VAL A 285
GLU A 188
ARG A 191
GLY A 194
LEU A 193
 None
 1.16A 5m5cB-1v0dA:
undetectable		 5m5cB-1v0dA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 4 HIS A 263
LEU A 200
TYR A 205
GLY A 169
 None
 1.07A 6n91A-1v0dA:
undetectable		 6n91A-1v0dA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1v0d DNA FRAGMENTATION
FACTOR 40 KDA
SUBUNIT
(Mus
musculus) 		4 / 4 HIS A 263
LEU A 200
TYR A 205
GLY A 169
 None
 1.06A 6n91B-1v0dA:
undetectable		 6n91B-1v0dA:
13.62