SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 VAL A 551
GLY A 552
LEU A 593
LEU A 620
SER A 619
VAL  A 551 ( 0.6A)
GLY  A 552 ( 0.0A)
LEU  A 593 ( 0.5A)
LEU  A 620 ( 0.6A)
SER  A 619 ( 0.0A)
1.04A 1fduA-1v0fA:
undetectable
1fduA-1v0fA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 6 PHE A 718
GLU A 721
GLY A 720
SER A 700
PHE  A 718 ( 1.3A)
GLU  A 721 ( 0.6A)
GLY  A 720 ( 0.0A)
SER  A 700 ( 0.0A)
1.16A 1kqbC-1v0fA:
undetectable
1kqbD-1v0fA:
undetectable
1kqbC-1v0fA:
14.61
1kqbD-1v0fA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 6 GLU A 309
ILE A 714
TYR A 713
GLY A 755
GLU  A 309 ( 0.6A)
ILE  A 714 ( 0.7A)
TYR  A 713 ( 1.3A)
GLY  A 755 ( 0.0A)
1.05A 1maaB-1v0fA:
undetectable
1maaD-1v0fA:
undetectable
1maaB-1v0fA:
22.78
1maaD-1v0fA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 VAL A 704
VAL A 702
TRP A 328
VAL  A 704 ( 0.6A)
VAL  A 702 ( 0.5A)
TRP  A 328 ( 0.5A)
0.95A 1w5uA-1v0fA:
undetectable
1w5uB-1v0fA:
undetectable
1w5uA-1v0fA:
3.41
1w5uB-1v0fA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 6 TYR A 716
GLY A 597
SER A 605
ARG A 596
TYR  A 716 ( 1.3A)
GLY  A 597 ( 0.0A)
SER  A 605 ( 0.0A)
ARG  A 596 ( 0.6A)
1.24A 2a3cA-1v0fA:
undetectable
2a3cA-1v0fA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 6 TYR A 716
GLY A 597
SER A 605
ARG A 596
TYR  A 716 ( 1.3A)
GLY  A 597 ( 0.0A)
SER  A 605 ( 0.0A)
ARG  A 596 ( 0.6A)
1.22A 2a3cB-1v0fA:
undetectable
2a3cB-1v0fA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_D_TPFD2473_1
(CYTOCHROME P450 121)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 10 THR A 465
VAL A 464
ASN A 495
THR A 434
ALA A 436
THR  A 465 ( 0.9A)
VAL  A 464 ( 0.6A)
ASN  A 495 ( 0.6A)
THR  A 434 ( 0.9A)
ALA  A 436 ( 0.0A)
1.32A 2ij7D-1v0fA:
0.0
2ij7D-1v0fA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 VAL A 702
TRP A 328
VAL A 704
VAL  A 702 ( 0.5A)
TRP  A 328 ( 0.5A)
VAL  A 704 ( 0.6A)
0.98A 2izqC-1v0fA:
undetectable
2izqD-1v0fA:
undetectable
2izqC-1v0fA:
3.41
2izqD-1v0fA:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 PRO A 632
GLY A 705
TYR A 716
PRO  A 632 ( 1.1A)
GLY  A 705 ( 0.0A)
TYR  A 716 ( 1.3A)
0.65A 2vouB-1v0fA:
undetectable
2vouB-1v0fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 PRO A 632
GLY A 705
TYR A 716
PRO  A 632 ( 1.1A)
GLY  A 705 ( 0.0A)
TYR  A 716 ( 1.3A)
0.66A 2vouC-1v0fA:
undetectable
2vouC-1v0fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 7 VAL A 464
ILE A 433
ALA A 442
GLY A 466
VAL  A 464 ( 0.6A)
ILE  A 433 ( 0.7A)
ALA  A 442 ( 0.0A)
GLY  A 466 ( 0.0A)
0.75A 2xrzB-1v0fA:
undetectable
2xrzB-1v0fA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 6 GLN A 330
GLY A 705
HIS A 350
TRP A 328
GLN  A 330 ( 0.6A)
GLY  A 705 ( 0.0A)
HIS  A 350 ( 1.0A)
TRP  A 328 ( 0.5A)
1.46A 3ai8B-1v0fA:
undetectable
3ai8B-1v0fA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 TYR A 382
ARG A 354
SER A 353
TYR  A 382 ( 1.3A)
ARG  A 354 ( 0.6A)
SER  A 353 ( 0.0A)
1.11A 4khpI-1v0fA:
undetectable
4khpJ-1v0fA:
undetectable
4khpI-1v0fA:
11.48
4khpJ-1v0fA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 PRO A 372
TYR A 324
GLY A 346
ASN A 326
MET A 345
PRO  A 372 ( 1.1A)
TYR  A 324 ( 1.3A)
GLY  A 346 ( 0.0A)
ASN  A 326 ( 0.6A)
MET  A 345 ( 0.0A)
1.34A 4kosA-1v0fA:
undetectable
4kosA-1v0fA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 PRO A 372
TYR A 324
GLY A 346
ASN A 326
MET A 345
PRO  A 372 ( 1.1A)
TYR  A 324 ( 1.3A)
GLY  A 346 ( 0.0A)
ASN  A 326 ( 0.6A)
MET  A 345 ( 0.0A)
1.36A 4kovA-1v0fA:
undetectable
4kovA-1v0fA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 PRO A 372
TYR A 324
GLY A 346
ASN A 326
MET A 345
PRO  A 372 ( 1.1A)
TYR  A 324 ( 1.3A)
GLY  A 346 ( 0.0A)
ASN  A 326 ( 0.6A)
MET  A 345 ( 0.0A)
1.34A 4kowA-1v0fA:
0.0
4kowA-1v0fA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 11 PRO A 372
TYR A 324
GLY A 346
ASN A 326
MET A 345
PRO  A 372 ( 1.1A)
TYR  A 324 ( 1.3A)
GLY  A 346 ( 0.0A)
ASN  A 326 ( 0.6A)
MET  A 345 ( 0.0A)
1.38A 4koxA-1v0fA:
0.0
4koxA-1v0fA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOY_A_CSCA214_1
(UNCHARACTERIZED
PROTEIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 11 PRO A 372
TYR A 324
GLY A 346
ASN A 326
MET A 345
PRO  A 372 ( 1.1A)
TYR  A 324 ( 1.3A)
GLY  A 346 ( 0.0A)
ASN  A 326 ( 0.6A)
MET  A 345 ( 0.0A)
1.37A 4koyA-1v0fA:
undetectable
4koyA-1v0fA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 ASP A 731
ARG A 349
ARG A 354
ASP  A 731 ( 0.6A)
ARG  A 349 ( 0.6A)
ARG  A 354 ( 0.6A)
0.96A 4x5iA-1v0fA:
0.0
4x5iA-1v0fA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 SER A 605
GLU A 651
GLU A 721
SER  A 605 ( 0.0A)
GLU  A 651 ( 0.6A)
GLU  A 721 ( 0.6A)
0.87A 4ymgB-1v0fA:
undetectable
4ymgB-1v0fA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 LEU A 640
ARG A 672
TYR A 670
TYR A 592
LEU A 607
LEU  A 640 ( 0.5A)
ARG  A 672 ( 0.6A)
TYR  A 670 ( 1.3A)
TYR  A 592 ( 1.3A)
LEU  A 607 ( 0.5A)
1.33A 5czyA-1v0fA:
undetectable
5czyA-1v0fA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 6 THR A 483
ALA A 474
THR A 475
VAL A 453
THR  A 483 ( 0.9A)
ALA  A 474 ( 0.0A)
THR  A 475 ( 0.9A)
VAL  A 453 ( 0.6A)
0.74A 5ecoA-1v0fA:
undetectable
5ecoA-1v0fA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 TYR A 592
SER A 610
TRP A 678
TYR  A 592 ( 1.3A)
SER  A 610 ( 0.0A)
TRP  A 678 ( 0.5A)
0.98A 5n8jB-1v0fA:
undetectable
5n8jB-1v0fA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 TYR A 592
SER A 610
TRP A 678
TYR  A 592 ( 1.3A)
SER  A 610 ( 0.0A)
TRP  A 678 ( 0.5A)
0.93A 5n8jA-1v0fA:
undetectable
5n8jA-1v0fA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
3 / 3 TYR A 592
SER A 610
TRP A 678
TYR  A 592 ( 1.3A)
SER  A 610 ( 0.0A)
TRP  A 678 ( 0.5A)
0.90A 5n8jD-1v0fA:
undetectable
5n8jD-1v0fA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 VAL A 473
VAL A 457
GLY A 431
THR A 465
GLY A 466
VAL  A 473 ( 0.6A)
VAL  A 457 ( 0.6A)
GLY  A 431 ( 0.0A)
THR  A 465 ( 0.9A)
GLY  A 466 ( 0.0A)
1.08A 6brdC-1v0fA:
undetectable
6brdC-1v0fA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 5 ARG A 784
GLY A 782
ASN A 781
ASP A 779
ARG  A 784 ( 0.6A)
GLY  A 782 ( 0.0A)
ASN  A 781 ( 0.6A)
ASP  A 779 ( 0.6A)
1.38A 6dwjB-1v0fA:
undetectable
6dwjD-1v0fA:
undetectable
6dwjB-1v0fA:
21.34
6dwjD-1v0fA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 5 ASN A 732
TYR A 325
GLY A 346
HIS A 743
ASN  A 732 ( 0.6A)
TYR  A 325 ( 1.3A)
GLY  A 346 ( 0.0A)
HIS  A 743 ( 1.0A)
1.29A 6gh9A-1v0fA:
undetectable
6gh9A-1v0fA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 5 TYR A 278
VAL A 267
PHE A 311
GLY A 275
TYR  A 278 ( 1.3A)
VAL  A 267 ( 0.5A)
PHE  A 311 ( 1.3A)
GLY  A 275 ( 0.0A)
1.32A 6hd4A-1v0fA:
undetectable
6hd4A-1v0fA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 8 ASP A 420
ARG A 398
ARG A 513
ASN A 534
ASP  A 420 ( 0.6A)
ARG  A 398 ( 0.6A)
ARG  A 513 ( 0.6A)
ASN  A 534 ( 0.6A)
1.03A 6hisB-1v0fA:
undetectable
6hisC-1v0fA:
undetectable
6hisB-1v0fA:
8.39
6hisC-1v0fA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 8 ASP A 420
ARG A 398
ARG A 513
ASN A 534
ASP  A 420 ( 0.6A)
ARG  A 398 ( 0.6A)
ARG  A 513 ( 0.6A)
ASN  A 534 ( 0.6A)
1.01A 6hisC-1v0fA:
undetectable
6hisD-1v0fA:
undetectable
6hisC-1v0fA:
8.39
6hisD-1v0fA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
4 / 8 ASN A 534
ASP A 420
ARG A 398
ARG A 513
ASN  A 534 ( 0.6A)
ASP  A 420 ( 0.6A)
ARG  A 398 ( 0.6A)
ARG  A 513 ( 0.6A)
1.01A 6hisA-1v0fA:
undetectable
6hisE-1v0fA:
undetectable
6hisA-1v0fA:
8.39
6hisE-1v0fA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_0
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)
1v0f ENDO-ALPHA-SIALIDASE
(Enterobacteria
phage
K1F)
5 / 12 PRO A 548
ILE A 571
TYR A 541
HIS A 542
THR A 524
PRO  A 548 ( 1.1A)
ILE  A 571 ( 0.7A)
TYR  A 541 ( 1.3A)
HIS  A 542 ( 1.0A)
THR  A 524 ( 0.9A)
1.29A 6hloA-1v0fA:
0.0
6hloA-1v0fA:
21.46