SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v0m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 7 GLU A 236
LEU A 237
VAL A 250
LEU A 222
 XDN  A1303 (-2.8A)
None
None
None
 1.02A 1hk3A-1v0mA:
0.0		 1hk3A-1v0mA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 12 LEU A 222
LEU A 228
VAL A 230
ILE A 199
TYR A 186
 None
 1.10A 1s19A-1v0mA:
undetectable		 1s19A-1v0mA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 10 PHE A 204
LEU A 228
VAL A 230
GLY A 229
VAL A 257
 None
 1.39A 2cp4A-1v0mA:
undetectable		 2cp4A-1v0mA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 ASN A 170
ILE A 199
MET A 188
 None
 0.82A 2h42C-1v0mA:
undetectable		 2h42C-1v0mA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 6 ILE A  20
ARG A  24
LEU A  25
ASP A 272
 None
 0.85A 2rlfA-1v0mA:
undetectable
2rlfD-1v0mA:
undetectable		 2rlfA-1v0mA:
8.70
2rlfD-1v0mA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 10 GLN A  89
MET A 105
ILE A 109
VAL A 125
VAL A 126
 None
 1.16A 3fhjA-1v0mA:
undetectable		 3fhjA-1v0mA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 10 GLN A  89
MET A 105
ILE A 109
VAL A 125
VAL A 126
 None
 1.17A 3fhjB-1v0mA:
undetectable		 3fhjB-1v0mA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 10 GLN A  89
MET A 105
ILE A 109
VAL A 125
VAL A 126
 None
 1.17A 3fhjC-1v0mA:
undetectable		 3fhjC-1v0mA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 10 GLN A  89
MET A 105
ILE A 109
VAL A 125
VAL A 126
 None
 1.19A 3fhjE-1v0mA:
undetectable		 3fhjE-1v0mA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 TRP A 274
VAL A 265
TRP A 266
 XDN  A1303 ( 4.1A)
None
XDN  A1303 ( 4.1A)
 0.89A 3zq8C-1v0mA:
undetectable
3zq8D-1v0mA:
undetectable		 3zq8C-1v0mA:
4.12
3zq8D-1v0mA:
4.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 12 ASN A  39
LEU A 282
PHE A 283
PHE A  16
GLY A  17
 None
 1.31A 4pevC-1v0mA:
undetectable		 4pevC-1v0mA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 11 PHE A 204
ASP A 171
VAL A 189
TYR A 169
PHE A 225
 None
 1.17A 4xp4A-1v0mA:
undetectable		 4xp4A-1v0mA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 10 PHE A 204
ASP A 171
VAL A 189
TYR A 169
PHE A 225
 None
 1.21A 4xpbA-1v0mA:
0.0		 4xpbA-1v0mA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		5 / 12 ILE A  20
SER A  22
ALA A  21
ALA A  19
VAL A 268
 None
 1.11A 5n0oB-1v0mA:
undetectable		 5n0oB-1v0mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 6 ARG A  14
ARG A 219
LEU A 222
ASP A 253
 IMD  A1305 (-3.6A)
None
None
None
 1.20A 5tdzA-1v0mA:
2.5		 5tdzA-1v0mA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1v0m ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 8 ASP A 191
ARG A 138
VAL A 174
GLN A  89
 None
 1.09A 6fbvD-1v0mA:
undetectable		 6fbvD-1v0mA:
14.29