SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1v15 COLICIN E9
(Escherichia
coli) 		5 / 9 PHE A  50
PHE A  53
VAL A  57
ILE A 119
THR A 122
 None
 1.36A 3t3rB-1v15A:
undetectable		 3t3rB-1v15A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1v15 COLICIN E9
(Escherichia
coli) 		5 / 9 PHE A  50
PHE A  53
VAL A  57
ILE A 119
THR A 122
 None
 1.39A 3t3rC-1v15A:
undetectable		 3t3rC-1v15A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1v15 COLICIN E9
(Escherichia
coli) 		4 / 8 ASP A  51
VAL A 113
SER A  49
GLY A   9
 None
 0.92A 4m48A-1v15A:
undetectable		 4m48A-1v15A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1v15 COLICIN E9
(Escherichia
coli) 		3 / 3 HIS A 102
HIS A 131
HIS A 127
 ZN  A1132 (-3.2A)
ZN  A1132 (-3.3A)
ZN  A1132 (-3.4A)
 0.73A 6giqa-1v15A:
undetectable		 6giqa-1v15A:
12.16