SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
ASP A 251
 None
 0.80A 1bx4A-1v19A:
32.1		 1bx4A-1v19A:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 8 ALA A 213
LEU A 184
LEU A 180
HIS A 130
 None
 0.94A 1ereE-1v19A:
undetectable		 1ereE-1v19A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 VAL A  53
GLY A  54
LEU A 113
SER A 146
PHE A 118
 None
 0.86A 1fduC-1v19A:
5.0		 1fduC-1v19A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.23A 1jhoA-1v19A:
undetectable		 1jhoA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.25A 1jhrA-1v19A:
undetectable		 1jhrA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.24A 1jhyA-1v19A:
undetectable		 1jhyA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.26A 1l4nA-1v19A:
undetectable		 1l4nA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.27A 1l5kA-1v19A:
undetectable		 1l5kA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.26A 1l5lA-1v19A:
undetectable		 1l5lA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.26A 1l5mA-1v19A:
undetectable		 1l5mA-1v19A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
ASP A 251
 None
 0.85A 1liiA-1v19A:
32.1		 1liiA-1v19A:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
ASP A 251
 None
 0.91A 1likA-1v19A:
31.5		 1likA-1v19A:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 8 ALA A   7
ALA A 117
SER A 139
LEU A 138
 None
 0.72A 2bxgA-1v19A:
undetectable		 2bxgA-1v19A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 10 ALA A   7
LEU A 113
ALA A 117
SER A 139
LEU A 138
 None
 1.05A 2bxgB-1v19A:
undetectable		 2bxgB-1v19A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.26A 2pkkA-1v19A:
29.8		 2pkkA-1v19A:
27.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.26A 2pkmA-1v19A:
29.7		 2pkmA-1v19A:
27.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 11 LEU A  14
LEU A  90
ARG A  91
VAL A 101
ASP A 287
 None
 1.23A 2qeiA-1v19A:
undetectable		 2qeiA-1v19A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 6 PHE A  79
PHE A  52
GLY A  33
GLY A  34
 None
 0.99A 2qr2A-1v19A:
4.4
2qr2B-1v19A:
4.3		 2qr2A-1v19A:
25.00
2qr2B-1v19A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 5 GLY A  33
GLY A  34
PHE A  79
PHE A  52
 None
 0.97A 2qr2A-1v19A:
4.4
2qr2B-1v19A:
4.2		 2qr2A-1v19A:
25.00
2qr2B-1v19A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 PHE A 145
ALA A 117
ALA A   7
GLY A   8
GLY A  54
 None
 1.31A 2v7bA-1v19A:
2.3		 2v7bA-1v19A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A 256
GLY A 260
LEU A  43
ALA A  42
LEU A 277
LEU A 276
 None
 1.46A 2yqzA-1v19A:
3.9		 2yqzA-1v19A:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A 256
GLY A 260
LEU A  43
ALA A  42
LEU A 277
LEU A 276
 None
 1.46A 2yqzB-1v19A:
5.1		 2yqzB-1v19A:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 LEU A 123
MET A 150
ALA A 153
VAL A 160
LEU A 180
 None
 1.31A 3b0wB-1v19A:
undetectable		 3b0wB-1v19A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 289
GLY A 290
ASP A 245
GLY A  33
ASN A  38
 None
 1.23A 3k13A-1v19A:
undetectable		 3k13A-1v19A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 289
GLY A 290
ASP A 245
GLY A  33
ASN A  38
 None
 1.23A 3k13B-1v19A:
undetectable		 3k13B-1v19A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 289
GLY A 290
ASP A 245
GLY A  33
ASN A  38
 None
 1.24A 3k13C-1v19A:
undetectable		 3k13C-1v19A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 215
LEU A 189
ARG A 159
GLU A 269
ARG A 232
 None
 1.13A 3k39D-1v19A:
undetectable		 3k39D-1v19A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 215
LEU A 189
ARG A 159
GLU A 269
ARG A 232
 None
 1.14A 3k39N-1v19A:
undetectable		 3k39N-1v19A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 215
LEU A 189
ARG A 159
GLU A 269
ARG A 232
 None
 1.12A 3k39O-1v19A:
undetectable		 3k39O-1v19A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLU A 215
LEU A 189
ARG A 159
GLU A 269
ARG A 232
 None
 1.11A 3k39P-1v19A:
undetectable		 3k39P-1v19A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
GLY A 248
ASP A 251
 None
 0.71A 3uboA-1v19A:
35.2		 3uboA-1v19A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 3uboB-1v19A:
36.1		 3uboB-1v19A:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 7 VAL A 281
GLY A 286
VAL A  37
VAL A  41
 None
 0.72A 3ufnB-1v19A:
undetectable		 3ufnB-1v19A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.86A 3uq6A-1v19A:
33.2		 3uq6A-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.10A 3uq6A-1v19A:
33.2		 3uq6A-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		7 / 12 LEU A 170
GLY A  34
ALA A  35
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.05A 3uq6B-1v19A:
32.1		 3uq6B-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.82A 3vaqA-1v19A:
33.1		 3vaqA-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.07A 3vaqA-1v19A:
33.1		 3vaqA-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		7 / 12 LEU A 170
GLY A  34
ALA A  35
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.02A 3vaqB-1v19A:
31.7		 3vaqB-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.83A 3vasA-1v19A:
28.4		 3vasA-1v19A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.07A 3vasA-1v19A:
28.4		 3vasA-1v19A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.79A 3vasB-1v19A:
23.7		 3vasB-1v19A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.05A 3vasB-1v19A:
23.7		 3vasB-1v19A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
ALA A  35
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.07A 4dc3A-1v19A:
31.4		 4dc3A-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
ALA A  35
ASN A  38
GLY A 248
ASP A 251
 None
 0.93A 4dc3A-1v19A:
31.4		 4dc3A-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.81A 4dc3B-1v19A:
28.3		 4dc3B-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.06A 4dc3B-1v19A:
28.3		 4dc3B-1v19A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4e3aA-1v19A:
36.2		 4e3aA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		7 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
GLY A 248
ASP A 251
 None
 1.02A 4e3aB-1v19A:
36.4		 4e3aB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 7 TYR A 103
ARG A 105
ILE A 134
GLY A  33
 None
 0.95A 4eqlA-1v19A:
1.1		 4eqlA-1v19A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 8 TYR A 257
LEU A 277
GLY A 278
PHE A 253
 None
 0.84A 4iqqD-1v19A:
undetectable		 4iqqD-1v19A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4jksA-1v19A:
36.3		 4jksA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4jksB-1v19A:
36.2		 4jksB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.54A 4jkuA-1v19A:
33.3		 4jkuA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4jkuB-1v19A:
36.2		 4jkuB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4k8cA-1v19A:
33.2		 4k8cA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.54A 4k8cB-1v19A:
36.2		 4k8cB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4k8kA-1v19A:
36.1		 4k8kA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4k8kB-1v19A:
36.2		 4k8kB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4k8pA-1v19A:
36.1		 4k8pA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4k8pB-1v19A:
36.2		 4k8pB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.06A 4k8tA-1v19A:
36.2		 4k8tA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4k8tB-1v19A:
36.2		 4k8tB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4k93A-1v19A:
36.2		 4k93A-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.06A 4k93B-1v19A:
36.2		 4k93B-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4k9cA-1v19A:
36.2		 4k9cA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.05A 4k9cB-1v19A:
36.2		 4k9cB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.06A 4k9iA-1v19A:
36.2		 4k9iA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4k9iB-1v19A:
36.2		 4k9iB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4kadA-1v19A:
36.2		 4kadA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.07A 4kadB-1v19A:
33.2		 4kadB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.54A 4kahA-1v19A:
33.3		 4kahA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4kahB-1v19A:
36.2		 4kahB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.54A 4kalA-1v19A:
36.2		 4kalA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4kalB-1v19A:
36.2		 4kalB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.56A 4kanA-1v19A:
33.3		 4kanA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.56A 4kanB-1v19A:
36.2		 4kanB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4kbeA-1v19A:
33.3		 4kbeA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4kbeB-1v19A:
33.2		 4kbeB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 9 THR A 135
GLY A  54
LEU A 113
GLU A  36
GLY A 110
 None
 1.29A 4kqiA-1v19A:
undetectable		 4kqiA-1v19A:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 6 TYR A 103
ARG A 105
ILE A 134
GLY A  33
 None
 0.96A 4l39A-1v19A:
1.1		 4l39A-1v19A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 6 TYR A 103
ARG A 105
ILE A 134
GLY A  34
 None
 0.91A 4l39A-1v19A:
1.1		 4l39A-1v19A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.55A 4lbgA-1v19A:
36.2		 4lbgA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.56A 4lbgB-1v19A:
36.2		 4lbgB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4lbxA-1v19A:
36.2		 4lbxA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4lbxB-1v19A:
36.1		 4lbxB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4lc4A-1v19A:
36.1		 4lc4A-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 138
GLU A  36
ASP A 251
 None
 1.08A 4lc4B-1v19A:
36.2		 4lc4B-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.57A 4lcaA-1v19A:
36.2		 4lcaA-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLU A  36
ASP A 251
 None
 0.54A 4lcaB-1v19A:
36.2		 4lcaB-1v19A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 LEU A 170
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.97A 4n09A-1v19A:
30.9		 4n09A-1v19A:
28.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.99A 4n09B-1v19A:
30.7		 4n09B-1v19A:
28.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.99A 4n09C-1v19A:
30.7		 4n09C-1v19A:
28.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 248
ASP A 251
 None
 1.12A 4n09C-1v19A:
30.7		 4n09C-1v19A:
28.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  34
ASN A  38
LEU A 138
GLY A 250
ASP A 251
 None
 1.48A 4n09C-1v19A:
30.7		 4n09C-1v19A:
28.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 1.01A 4n09D-1v19A:
30.6		 4n09D-1v19A:
28.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 11 GLY A  33
GLY A  34
GLY A  62
PHE A  79
PHE A  52
 None
 1.17A 4qoiA-1v19A:
4.4
4qoiB-1v19A:
4.4		 4qoiA-1v19A:
25.55
4qoiB-1v19A:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A 290
GLU A 289
LEU A  43
LEU A 258
ALA A 274
 None
 1.19A 4wcxC-1v19A:
3.1		 4wcxC-1v19A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		3 / 3 ARG A  91
ASP A 245
TYR A  31
 None
 0.81A 4yo9B-1v19A:
undetectable		 4yo9B-1v19A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		3 / 4 ARG A 100
GLY A  99
GLU A  92
 None
 0.59A 4z2dB-1v19A:
undetectable
4z2dC-1v19A:
undetectable		 4z2dB-1v19A:
21.31
4z2dC-1v19A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 11 ALA A  42
ALA A 252
VAL A 281
LEU A 277
LEU A 297
 None
 1.05A 5eb5A-1v19A:
0.0		 5eb5A-1v19A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 4 LEU A 138
LEU A 113
GLY A   8
GLU A  36
 None
 1.15A 5hhjA-1v19A:
0.0		 5hhjA-1v19A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 ALA A 252
ALA A  42
LEU A  46
ALA A 282
GLY A 278
 None
 1.49A 5jglA-1v19A:
4.6		 5jglA-1v19A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		6 / 12 LEU A 170
GLY A  33
GLY A  34
ASN A  38
GLY A 248
ASP A 251
 None
 0.83A 5kb5A-1v19A:
31.6		 5kb5A-1v19A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 6 GLU A  29
TYR A  31
GLY A  33
GLY A  34
 None
 0.88A 5x7pB-1v19A:
3.0		 5x7pB-1v19A:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		5 / 12 LEU A 162
PRO A 136
THR A 135
GLU A  36
GLY A 110
 None
 1.21A 5xipC-1v19A:
undetectable		 5xipC-1v19A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		3 / 3 TYR A  93
PRO A  95
LEU A  94
 None
 0.84A 6beoA-1v19A:
undetectable		 6beoA-1v19A:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 8 GLY A 250
PHE A 191
VAL A 164
GLY A 224
 None
 0.77A 6hu9H-1v19A:
undetectable
6hu9e-1v19A:
undetectable		 6hu9H-1v19A:
15.93
6hu9e-1v19A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 6 ARG A  55
ALA A   7
THR A 135
ALA A 112
 None
 1.05A 6ma6A-1v19A:
undetectable		 6ma6A-1v19A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 1v19 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Thermus
thermophilus) 		4 / 8 ALA A 291
GLY A 278
LEU A 277
ALA A 255
 None
 0.65A 6mdqA-1v19A:
undetectable		 6mdqA-1v19A:
13.77