SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 1c9sC-1v1pA:
undetectable
1c9sD-1v1pA:
undetectable
1c9sC-1v1pA:
19.02
1c9sD-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 1c9sD-1v1pA:
undetectable
1c9sE-1v1pA:
undetectable
1c9sD-1v1pA:
19.02
1c9sE-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.48A 1c9sE-1v1pA:
undetectable
1c9sF-1v1pA:
undetectable
1c9sE-1v1pA:
19.02
1c9sF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 1c9sL-1v1pA:
undetectable
1c9sM-1v1pA:
undetectable
1c9sL-1v1pA:
19.02
1c9sM-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 1c9sM-1v1pA:
undetectable
1c9sN-1v1pA:
undetectable
1c9sM-1v1pA:
19.02
1c9sN-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 1c9sO-1v1pA:
undetectable
1c9sP-1v1pA:
undetectable
1c9sO-1v1pA:
19.02
1c9sP-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 1c9sS-1v1pA:
undetectable
1c9sT-1v1pA:
undetectable
1c9sS-1v1pA:
19.02
1c9sT-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.48A 1gtfA-1v1pA:
undetectable
1gtfK-1v1pA:
undetectable
1gtfA-1v1pA:
19.02
1gtfK-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.49A 1gtfA-1v1pA:
undetectable
1gtfB-1v1pA:
undetectable
1gtfA-1v1pA:
19.02
1gtfB-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.48A 1gtfB-1v1pA:
undetectable
1gtfC-1v1pA:
undetectable
1gtfB-1v1pA:
19.02
1gtfC-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 1gtfE-1v1pA:
undetectable
1gtfF-1v1pA:
undetectable
1gtfE-1v1pA:
19.02
1gtfF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.48A 1gtfF-1v1pA:
undetectable
1gtfG-1v1pA:
undetectable
1gtfF-1v1pA:
19.02
1gtfG-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.48A 1gtfI-1v1pA:
undetectable
1gtfJ-1v1pA:
undetectable
1gtfI-1v1pA:
19.02
1gtfJ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 1gtfO-1v1pA:
undetectable
1gtfP-1v1pA:
undetectable
1gtfO-1v1pA:
19.02
1gtfP-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 1gtfP-1v1pA:
undetectable
1gtfQ-1v1pA:
undetectable
1gtfP-1v1pA:
19.02
1gtfQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 1gtfT-1v1pA:
undetectable
1gtfU-1v1pA:
undetectable
1gtfT-1v1pA:
19.02
1gtfU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 8 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.49A 1gtnA-1v1pA:
undetectable
1gtnB-1v1pA:
undetectable
1gtnA-1v1pA:
19.02
1gtnB-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 8 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 1gtnP-1v1pA:
undetectable
1gtnQ-1v1pA:
undetectable
1gtnP-1v1pA:
19.02
1gtnQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.41A 1gtnR-1v1pA:
undetectable
1gtnS-1v1pA:
undetectable
1gtnR-1v1pA:
19.02
1gtnS-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.42A 1gtnS-1v1pA:
undetectable
1gtnT-1v1pA:
undetectable
1gtnS-1v1pA:
19.02
1gtnT-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
4 / 4 LEU A 159
GLY A 167
ASP A 182
TYR A 160
None
1.43A 1oxrA-1v1pA:
undetectable
1oxrA-1v1pA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.48A 1utdC-1v1pA:
undetectable
1utdD-1v1pA:
undetectable
1utdC-1v1pA:
19.02
1utdD-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 8 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.47A 1utdF-1v1pA:
undetectable
1utdG-1v1pA:
undetectable
1utdF-1v1pA:
19.02
1utdG-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.47A 1utdG-1v1pA:
undetectable
1utdH-1v1pA:
undetectable
1utdG-1v1pA:
19.02
1utdH-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 1utdA-1v1pA:
undetectable
1utdK-1v1pA:
undetectable
1utdA-1v1pA:
19.02
1utdK-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 1utdN-1v1pA:
undetectable
1utdO-1v1pA:
undetectable
1utdN-1v1pA:
19.02
1utdO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 1utdR-1v1pA:
undetectable
1utdS-1v1pA:
undetectable
1utdR-1v1pA:
19.02
1utdS-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
4 / 6 HIS A  29
ASP A  24
ASP A  27
TYR A  31
None
1.15A 2lh8A-1v1pA:
0.0
2lh8A-1v1pA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 ILE A 201
LYS A 137
GLU A 144
LEU A 145
LYS A 148
None
1.02A 3f78A-1v1pA:
undetectable
3f78A-1v1pA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 8 ILE A 149
ILE A 135
PHE A 133
LEU A 173
VAL A 179
None
1.35A 3ua5A-1v1pA:
undetectable
3ua5A-1v1pA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
4 / 5 ARG A 150
LEU A 153
VAL A 206
ASP A 146
None
1.08A 3ufnA-1v1pA:
0.0
3ufnB-1v1pA:
0.0
3ufnA-1v1pA:
18.40
3ufnB-1v1pA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
3 / 3 PHE A 147
VAL A 206
ILE A 204
None
0.53A 4emaA-1v1pA:
undetectable
4emaA-1v1pA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 11 GLU A 180
ILE A 170
LEU A 187
GLY A 167
TYR A 160
None
1.41A 4foxF-1v1pA:
0.0
4foxF-1v1pA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
4 / 7 GLY A 193
ASP A 194
GLY A  68
GLU A  72
None
0.88A 4koeA-1v1pA:
undetectable
4koeB-1v1pA:
undetectable
4koeD-1v1pA:
undetectable
4koeA-1v1pA:
21.22
4koeB-1v1pA:
21.22
4koeD-1v1pA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 12 ILE A 181
THR A 112
THR A 114
LEU A 145
LEU A 173
None
1.10A 4qynB-1v1pA:
undetectable
4qynB-1v1pA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 12 ILE A 181
THR A 112
THR A 114
LEU A 145
LEU A 173
None
1.08A 4qzuA-1v1pA:
undetectable
4qzuA-1v1pA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 12 ILE A 201
LEU A 142
ILE A 169
ARG A 150
ILE A 204
None
1.04A 4x5jA-1v1pA:
undetectable
4x5jA-1v1pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
4 / 7 GLY A 193
ASP A 194
GLY A  68
GLU A  72
None
0.90A 4z53A-1v1pA:
undetectable
4z53B-1v1pA:
undetectable
4z53A-1v1pA:
15.63
4z53B-1v1pA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5eeuE-1v1pA:
undetectable
5eeuF-1v1pA:
undetectable
5eeuE-1v1pA:
19.02
5eeuF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eeuN-1v1pA:
undetectable
5eeuO-1v1pA:
undetectable
5eeuN-1v1pA:
19.02
5eeuO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eeuP-1v1pA:
undetectable
5eeuQ-1v1pA:
undetectable
5eeuP-1v1pA:
19.02
5eeuQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 5eeuR-1v1pA:
undetectable
5eeuS-1v1pA:
undetectable
5eeuR-1v1pA:
19.02
5eeuS-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5eeuT-1v1pA:
undetectable
5eeuU-1v1pA:
undetectable
5eeuT-1v1pA:
19.02
5eeuU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 5eeuU-1v1pA:
undetectable
5eeuV-1v1pA:
undetectable
5eeuU-1v1pA:
19.02
5eeuV-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.48A 5eevE-1v1pA:
undetectable
5eevF-1v1pA:
undetectable
5eevE-1v1pA:
19.02
5eevF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eevN-1v1pA:
undetectable
5eevO-1v1pA:
undetectable
5eevN-1v1pA:
19.02
5eevO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eevP-1v1pA:
undetectable
5eevQ-1v1pA:
undetectable
5eevP-1v1pA:
19.02
5eevQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 5eevR-1v1pA:
undetectable
5eevS-1v1pA:
undetectable
5eevR-1v1pA:
19.02
5eevS-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5eevT-1v1pA:
undetectable
5eevU-1v1pA:
undetectable
5eevT-1v1pA:
19.02
5eevU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5eewE-1v1pA:
undetectable
5eewF-1v1pA:
undetectable
5eewE-1v1pA:
19.02
5eewF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eewN-1v1pA:
undetectable
5eewO-1v1pA:
undetectable
5eewN-1v1pA:
19.02
5eewO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eewP-1v1pA:
undetectable
5eewQ-1v1pA:
undetectable
5eewP-1v1pA:
19.02
5eewQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 5eewR-1v1pA:
undetectable
5eewS-1v1pA:
undetectable
5eewR-1v1pA:
19.02
5eewS-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5eewT-1v1pA:
undetectable
5eewU-1v1pA:
undetectable
5eewT-1v1pA:
19.02
5eewU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5eexE-1v1pA:
undetectable
5eexF-1v1pA:
undetectable
5eexE-1v1pA:
19.02
5eexF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eexN-1v1pA:
undetectable
5eexO-1v1pA:
undetectable
5eexN-1v1pA:
19.02
5eexO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eexP-1v1pA:
undetectable
5eexQ-1v1pA:
undetectable
5eexP-1v1pA:
19.02
5eexQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eexQ-1v1pA:
undetectable
5eexR-1v1pA:
undetectable
5eexQ-1v1pA:
19.02
5eexR-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5eexT-1v1pA:
undetectable
5eexU-1v1pA:
undetectable
5eexT-1v1pA:
19.02
5eexU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5eeyE-1v1pA:
undetectable
5eeyF-1v1pA:
undetectable
5eeyE-1v1pA:
19.02
5eeyF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eeyN-1v1pA:
undetectable
5eeyO-1v1pA:
undetectable
5eeyN-1v1pA:
19.02
5eeyO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eeyP-1v1pA:
undetectable
5eeyQ-1v1pA:
undetectable
5eeyP-1v1pA:
19.02
5eeyQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eeyQ-1v1pA:
undetectable
5eeyR-1v1pA:
undetectable
5eeyQ-1v1pA:
19.02
5eeyR-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5eeyT-1v1pA:
undetectable
5eeyU-1v1pA:
undetectable
5eeyT-1v1pA:
19.02
5eeyU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5eezE-1v1pA:
undetectable
5eezF-1v1pA:
undetectable
5eezE-1v1pA:
19.02
5eezF-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5eezJ-1v1pA:
undetectable
5eezK-1v1pA:
undetectable
5eezJ-1v1pA:
19.02
5eezK-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eezN-1v1pA:
undetectable
5eezO-1v1pA:
undetectable
5eezN-1v1pA:
19.02
5eezO-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eezP-1v1pA:
undetectable
5eezQ-1v1pA:
undetectable
5eezP-1v1pA:
19.02
5eezQ-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5eezQ-1v1pA:
undetectable
5eezR-1v1pA:
undetectable
5eezQ-1v1pA:
19.02
5eezR-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.43A 5eezR-1v1pA:
undetectable
5eezS-1v1pA:
undetectable
5eezR-1v1pA:
19.02
5eezS-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5eezT-1v1pA:
undetectable
5eezU-1v1pA:
undetectable
5eezT-1v1pA:
19.02
5eezU-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef0E-1v1pA:
undetectable
5ef0F-1v1pA:
undetectable
5ef0E-1v1pA:
19.02
5ef0F-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef0J-1v1pA:
undetectable
5ef0K-1v1pA:
undetectable
5ef0J-1v1pA:
19.02
5ef0K-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef0N-1v1pA:
undetectable
5ef0O-1v1pA:
undetectable
5ef0N-1v1pA:
19.02
5ef0O-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef0P-1v1pA:
undetectable
5ef0Q-1v1pA:
undetectable
5ef0P-1v1pA:
19.02
5ef0Q-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef0Q-1v1pA:
undetectable
5ef0R-1v1pA:
undetectable
5ef0Q-1v1pA:
19.02
5ef0R-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5ef0T-1v1pA:
undetectable
5ef0U-1v1pA:
undetectable
5ef0T-1v1pA:
19.02
5ef0U-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef1E-1v1pA:
undetectable
5ef1F-1v1pA:
undetectable
5ef1E-1v1pA:
19.02
5ef1F-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef1J-1v1pA:
undetectable
5ef1K-1v1pA:
undetectable
5ef1J-1v1pA:
19.02
5ef1K-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef1N-1v1pA:
undetectable
5ef1O-1v1pA:
undetectable
5ef1N-1v1pA:
19.02
5ef1O-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef1P-1v1pA:
undetectable
5ef1Q-1v1pA:
undetectable
5ef1P-1v1pA:
19.02
5ef1Q-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef1Q-1v1pA:
undetectable
5ef1R-1v1pA:
undetectable
5ef1Q-1v1pA:
19.02
5ef1R-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5ef1T-1v1pA:
undetectable
5ef1U-1v1pA:
undetectable
5ef1T-1v1pA:
19.02
5ef1U-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef2E-1v1pA:
undetectable
5ef2F-1v1pA:
undetectable
5ef2E-1v1pA:
19.02
5ef2F-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef2J-1v1pA:
undetectable
5ef2K-1v1pA:
undetectable
5ef2J-1v1pA:
19.02
5ef2K-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef2N-1v1pA:
undetectable
5ef2O-1v1pA:
undetectable
5ef2N-1v1pA:
19.02
5ef2O-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef2P-1v1pA:
undetectable
5ef2Q-1v1pA:
undetectable
5ef2P-1v1pA:
19.02
5ef2Q-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef2Q-1v1pA:
undetectable
5ef2R-1v1pA:
undetectable
5ef2Q-1v1pA:
19.02
5ef2R-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5ef2T-1v1pA:
undetectable
5ef2U-1v1pA:
undetectable
5ef2T-1v1pA:
19.02
5ef2U-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef3E-1v1pA:
undetectable
5ef3F-1v1pA:
undetectable
5ef3E-1v1pA:
19.02
5ef3F-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 SER A 198
GLY A 203
THR A 112
THR A 114
ILE A 204
None
1.47A 5ef3J-1v1pA:
undetectable
5ef3K-1v1pA:
undetectable
5ef3J-1v1pA:
19.02
5ef3K-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef3N-1v1pA:
undetectable
5ef3O-1v1pA:
undetectable
5ef3N-1v1pA:
19.02
5ef3O-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef3P-1v1pA:
undetectable
5ef3Q-1v1pA:
undetectable
5ef3P-1v1pA:
19.02
5ef3Q-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 9 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.44A 5ef3Q-1v1pA:
undetectable
5ef3R-1v1pA:
undetectable
5ef3Q-1v1pA:
19.02
5ef3R-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 10 GLY A 203
THR A 112
THR A 114
ILE A 204
SER A 198
None
1.45A 5ef3T-1v1pA:
undetectable
5ef3U-1v1pA:
undetectable
5ef3T-1v1pA:
19.02
5ef3U-1v1pA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 12 GLU A  72
LEU A  67
ASP A 194
GLY A 193
LEU A  64
None
1.41A 5kbwA-1v1pA:
undetectable
5kbwA-1v1pA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
5 / 12 GLU A  72
LEU A  67
ASP A 194
GLY A 193
LEU A  64
None
1.38A 5kc4E-1v1pA:
undetectable
5kc4E-1v1pA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
3 / 3 LEU A 153
LEU A 183
ARG A 150
None
0.68A 6fgcA-1v1pA:
undetectable
6fgcA-1v1pA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)
1v1p EXOTOXIN 1
(Staphylococcus
aureus)
3 / 3 LEU A 153
LEU A 183
ARG A 150
None
0.68A 6fgdA-1v1pA:
undetectable
6fgdA-1v1pA:
17.54