SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ALA A 118
GLU A 119
VAL A 195
MET A 181
 None
 0.92A 1hk2A-1v26A:
undetectable		 1hk2A-1v26A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 10 HIS A  85
ALA A  57
LEU A  64
MET A  95
GLY A  96
 None
 1.36A 1uhoA-1v26A:
undetectable		 1uhoA-1v26A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 7 MET A 228
TYR A  89
HIS A  82
HIS A  85
 None
 1.47A 2bytA-1v26A:
0.0		 2bytA-1v26A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 7 MET A 228
TYR A  89
HIS A  82
HIS A  85
 None
 1.47A 2bytD-1v26A:
0.0		 2bytD-1v26A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 5 ALA A 207
TRP A 392
LEU A 201
ALA A 208
 None
None
None
MYR  A1001 ( 3.9A)
 1.26A 2jstA-1v26A:
undetectable
2jstB-1v26A:
undetectable		 2jstA-1v26A:
10.30
2jstB-1v26A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ALA A 304
GLY A 302
GLY A 325
THR A 276
VAL A 274
 AMP  A1002 (-3.8A)
MYR  A1001 ( 3.5A)
MYR  A1001 ( 3.8A)
None
None
 1.05A 2okcA-1v26A:
undetectable		 2okcA-1v26A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 8 HIS A  41
PRO A 127
SER A  38
ASP A 150
 None
 1.24A 2p02A-1v26A:
undetectable		 2p02A-1v26A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ALA A 420
GLY A 384
VAL A 376
ASP A 423
 None
 0.84A 2uyqA-1v26A:
undetectable		 2uyqA-1v26A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 8 THR A 409
PRO A 410
ARG A 367
ALA A 369
 None
 1.15A 2v41G-1v26A:
undetectable
2v41H-1v26A:
undetectable		 2v41G-1v26A:
18.45
2v41H-1v26A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 6 LEU A 249
PRO A 237
ALA A 233
LEU A 236
ALA A 272
 None
None
None
MYR  A1001 ( 4.4A)
None
 1.48A 2vcvK-1v26A:
1.3		 2vcvK-1v26A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 8 TYR A  89
LEU A  99
ALA A 182
HIS A  85
 None
 1.03A 2wekA-1v26A:
3.9		 2wekA-1v26A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 9 ARG A 297
THR A 269
VAL A 268
LEU A 223
ALA A 272
 None
 1.33A 3ax7B-1v26A:
0.0		 3ax7B-1v26A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ALA A  88
MET A 228
SER A  38
PRO A 250
TYR A 160
 None
 1.32A 3cl9A-1v26A:
undetectable		 3cl9A-1v26A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 ARG A 199
ILE A 393
TRP A 392
 None
 0.94A 3e7iB-1v26A:
undetectable		 3e7iB-1v26A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.70A 3n62B-1v26A:
undetectable		 3n62B-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.67A 3n65B-1v26A:
undetectable		 3n65B-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.71A 3n66B-1v26A:
undetectable		 3n66B-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 ARG A 199
ILE A 393
TRP A 392
 None
 0.92A 3nw2B-1v26A:
undetectable		 3nw2B-1v26A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUM_A_CCSA375_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 4 GLN A 474
SER A 303
GLY A 441
LYS A 439
 None
None
None
MYR  A1001 ( 2.8A)
 1.32A 3rumA-1v26A:
0.0		 3rumA-1v26A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 7 GLU A 328
LEU A 388
PRO A 391
ILE A 393
 MG  A3001 (-3.0A)
None
None
None
 0.87A 3s56B-1v26A:
undetectable		 3s56B-1v26A:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 10 GLY A 358
ALA A 420
VAL A 428
GLU A 429
VAL A 334
 None
 1.00A 4da7A-1v26A:
undetectable		 4da7A-1v26A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 129
GLU A 443
HIS A 230
THR A 276
GLY A 441
 None
 1.33A 4hvcB-1v26A:
undetectable		 4hvcB-1v26A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLU A 161
THR A  48
HIS A  46
 None
 0.78A 4q15A-1v26A:
undetectable		 4q15A-1v26A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLU A 161
THR A  48
HIS A  46
 None
 0.74A 4q15B-1v26A:
undetectable		 4q15B-1v26A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 10 THR A 101
ALA A 102
ALA A  76
VAL A  98
GLY A 193
 None
 0.93A 4qvyK-1v26A:
undetectable
4qvyL-1v26A:
undetectable		 4qvyK-1v26A:
19.51
4qvyL-1v26A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 10 THR A 101
ALA A 102
ALA A  76
VAL A  98
GLY A 193
 None
 0.92A 4qvyY-1v26A:
undetectable
4qvyZ-1v26A:
undetectable		 4qvyY-1v26A:
19.51
4qvyZ-1v26A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLU A 161
THR A  48
HIS A  46
 None
 0.80A 4ydqB-1v26A:
undetectable		 4ydqB-1v26A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 6 GLU A  87
GLY A  72
ASP A  73
GLY A  96
 None
 0.88A 5cdnA-1v26A:
undetectable
5cdnB-1v26A:
undetectable		 5cdnA-1v26A:
24.27
5cdnB-1v26A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 6 GLU A  87
GLY A  72
ASP A  73
GLY A  96
 None
 0.89A 5cdnR-1v26A:
undetectable
5cdnS-1v26A:
undetectable		 5cdnR-1v26A:
24.27
5cdnS-1v26A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 5 GLU A 475
GLY A 442
SER A 303
GLY A 302
 None
None
None
MYR  A1001 ( 3.5A)
 1.13A 5kprA-1v26A:
undetectable		 5kprA-1v26A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 4 GLU A 110
PRO A 108
ILE A 111
LEU A 106
 None
 1.25A 5m45A-1v26A:
0.0		 5m45A-1v26A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 4 GLU A 110
PRO A 108
ILE A 111
LEU A 106
 None
 1.28A 5m45D-1v26A:
0.0		 5m45D-1v26A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 4 GLU A 110
PRO A 108
ILE A 111
LEU A 106
 None
 1.24A 5m45G-1v26A:
0.0		 5m45G-1v26A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 4 GLU A 110
PRO A 108
ILE A 111
LEU A 106
 None
 1.29A 5m45J-1v26A:
0.0		 5m45J-1v26A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 8 HIS A  41
PRO A 127
SER A  38
ASP A 150
 None
 1.20A 5t8sB-1v26A:
undetectable		 5t8sB-1v26A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 301
THR A 394
PRO A 331
 MYR  A1001 ( 3.9A)
None
MYR  A1001 ( 4.6A)
 0.58A 5v5zA-1v26A:
undetectable		 5v5zA-1v26A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.70A 5vuoB-1v26A:
undetectable		 5vuoB-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 129
GLU A 443
HIS A 230
THR A 276
GLY A 441
 None
 1.23A 5xipC-1v26A:
undetectable		 5xipC-1v26A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 129
GLU A 443
HIS A 230
THR A 276
GLY A 441
 None
 1.28A 5xiqA-1v26A:
undetectable		 5xiqA-1v26A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 129
GLU A 443
HIS A 230
THR A 276
GLY A 441
 None
 1.30A 5xiqD-1v26A:
undetectable		 5xiqD-1v26A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLU A 167
ASP A 169
PRO A 170
 None
 0.64A 6berA-1v26A:
undetectable		 6berA-1v26A:
4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 LEU A 216
GLY A 244
PHE A  90
 None
 0.59A 6exiC-1v26A:
4.6		 6exiC-1v26A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 8 HIS A  41
PRO A 127
SER A  38
ASP A 150
 None
 1.19A 6fbnB-1v26A:
undetectable		 6fbnB-1v26A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 8 HIS A  41
PRO A 127
SER A  38
ASP A 150
 None
 1.23A 6fcbA-1v26A:
undetectable		 6fcbA-1v26A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 ARG A  39
GLY A  43
GLU A  44
 None
 0.63A 6fgdA-1v26A:
undetectable		 6fgdA-1v26A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ASP A 169
TYR A  54
GLU A  25
GLU A  16
 None
 1.28A 6mn5B-1v26A:
undetectable		 6mn5B-1v26A:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ASP A 169
TYR A  54
GLU A  25
GLU A  16
 None
 1.32A 6mn5C-1v26A:
undetectable		 6mn5C-1v26A:
10.21