SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v27 REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 2
(Homo
sapiens) 		3 / 3 GLU A  89
GLU A 116
LEU A  23
 None
 0.68A 1v8bA-1v27A:
undetectable		 1v8bA-1v27A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v27 REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 2
(Homo
sapiens) 		3 / 3 GLU A  89
GLU A 116
LEU A  23
 None
 0.62A 1v8bB-1v27A:
undetectable		 1v8bB-1v27A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1v27 REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 2
(Homo
sapiens) 		5 / 12 ILE A  27
PHE A  50
LEU A  23
LEU A 122
LEU A  14
 None
 1.28A 4xumA-1v27A:
undetectable		 4xumA-1v27A:
17.45